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CHOP but Not Bendamustine Reverses EZH2 Y641 Mutation Induced MHC-I/II Loss in Human Lymphoma Models
Autor:
Vindi Jurinovic, Verena Passerini, Carolin Strobl, Louisa Catharina Adolph, Axel Lechner, Marion Subklewe, William David Keay, Martina Antoniolli, Martina Rudelius, Quentin Fichaux, Daniel J. Hodson, Oliver Weigert, Michael von Bergwelt
Publikováno v:
Blood. 138:2391-2391
Chemotherapy combined with anti-CD20 antibodies is the standard treatment for patients with symptomatic advanced stage follicular lymphoma (FL). We have previously shown that EZH2 gene mutations were predictive of differential efficacy of the chemoth