Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Louis-Félix Nothias"'
Autor:
Hyun Woo Kim, Chen Zhang, Raphael Reher, Mingxun Wang, Kelsey L. Alexander, Louis-Félix Nothias, Yoo Kyong Han, Hyeji Shin, Ki Yong Lee, Kyu Hyeong Lee, Myeong Ji Kim, Pieter C. Dorrestein, William H. Gerwick, Garrison W. Cottrell
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract The identification of molecular structure is essential for understanding chemical diversity and for developing drug leads from small molecules. Nevertheless, the structure elucidation of small molecules by Nuclear Magnetic Resonance (NMR) ex
Externí odkaz:
https://doaj.org/article/ea05f56befd0470b8ac790f9bec2bb4f
Autor:
Louis-Félix Nothias, Robin Schmid, Allison Garlet, Hunter Cameron, Sabrina Leoty-Okombi, Valérie André-Frei, Regine Fuchs, Pieter C. Dorrestein, Philipp Ternes
Publikováno v:
mSystems, Vol 9, Iss 2 (2024)
ABSTRACTAlthough metabolomics data acquisition and analysis technologies have become increasingly sophisticated over the past 5–10 years, deciphering a metabolite’s function from a description of its structure and its abundance in a given experim
Externí odkaz:
https://doaj.org/article/c1ef7ca7291d4893869b2cafd1899450
Autor:
Shan Zhang, Weizhi Song, Louis-Félix Nothias, Sneha P. Couvillion, Nicole Webster, Torsten Thomas
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Background Sponges are ancient sessile metazoans, which form with their associated microbial symbionts a complex functional unit called a holobiont. Sponges are a rich source of chemical diversity; however, there is limited knowledge of whic
Externí odkaz:
https://doaj.org/article/fdcde86183674004bc86d095592e0a74
Autor:
Jean-Luc Wolfender, Arnaud Gaudry, Adriano Rutz, Luis-Manuel Quiros-Guerrero, Louis-Félix Nothias, Emerson Ferreira Queiroz, Emmanuel Defossez, Pierre-Marie Allard
Publikováno v:
CHIMIA, Vol 76, Iss 11 (2022)
Metabolomics is playing an increasingly prominent role in chemical ecology and in the discovery of bioactive natural products (NPs). The identification of metabolites is a common/central objective in both research fields. NPs have significant biologi
Externí odkaz:
https://doaj.org/article/1831120062814ee7a98e59ed842669de
Autor:
Luis-Manuel Quiros-Guerrero, Louis-Félix Nothias, Arnaud Gaudry, Laurence Marcourt, Pierre-Marie Allard, Adriano Rutz, Bruno David, Emerson Ferreira Queiroz, Jean-Luc Wolfender
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Collections of natural extracts hold potential for the discovery of novel natural products with original modes of action. The prioritization of extracts from collections remains challenging due to the lack of a workflow that combines multiple-source
Externí odkaz:
https://doaj.org/article/bdb8b470f72841f2bb1d85e5ba900b5f
Autor:
Robin Schmid, Daniel Petras, Louis-Félix Nothias, Mingxun Wang, Allegra T. Aron, Annika Jagels, Hiroshi Tsugawa, Johannes Rainer, Mar Garcia-Aloy, Kai Dührkop, Ansgar Korf, Tomáš Pluskal, Zdeněk Kameník, Alan K. Jarmusch, Andrés Mauricio Caraballo-Rodríguez, Kelly C. Weldon, Melissa Nothias-Esposito, Alexander A. Aksenov, Anelize Bauermeister, Andrea Albarracin Orio, Carlismari O. Grundmann, Fernando Vargas, Irina Koester, Julia M. Gauglitz, Emily C. Gentry, Yannick Hövelmann, Svetlana A. Kalinina, Matthew A. Pendergraft, Morgan Panitchpakdi, Richard Tehan, Audrey Le Gouellec, Gajender Aleti, Helena Mannochio Russo, Birgit Arndt, Florian Hübner, Heiko Hayen, Hui Zhi, Manuela Raffatellu, Kimberly A. Prather, Lihini I. Aluwihare, Sebastian Böcker, Kerry L. McPhail, Hans-Ulrich Humpf, Uwe Karst, Pieter C. Dorrestein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Molecular networking connects mass spectra of molecules based on the similarity of their fragmentation patterns. However, during ionization, molecules commonly form multiple ion species with different fragmentation behavior. As a result, the
Externí odkaz:
https://doaj.org/article/c79c811ddd0b40428c0ef8e4c5a7fe4c
Publikováno v:
ACS Omega, Vol 6, Iss 17, Pp 11474-11487 (2021)
Externí odkaz:
https://doaj.org/article/bbefcb2d18fd4e3d934cf9273e7baa82
Autor:
Arnaud Gaudry, Florian Huber, Louis-Félix Nothias, Sylvian Cretton, Marcel Kaiser, Jean-Luc Wolfender, Pierre-Marie Allard
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
In natural products research, chemodiverse extracts coming from multiple organisms are explored for novel bioactive molecules, sometimes over extended periods. Samples are usually analyzed by liquid chromatography coupled with fragmentation mass spec
Externí odkaz:
https://doaj.org/article/3f1d11b81c5a41cebe49bfb5bf7c29f5
Autor:
Andrés Mauricio Caraballo-Rodríguez, Sara P. Puckett, Kathleen E. Kyle, Daniel Petras, Ricardo da Silva, Louis-Félix Nothias, Madeleine Ernst, Justin J. J. van der Hooft, Anupriya Tripathi, Mingxun Wang, Marcy J. Balunas, Jonathan L. Klassen, Pieter C. Dorrestein
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT Many ant species grow fungus gardens that predigest food as an essential step of the ants’ nutrient uptake. These symbiotic fungus gardens have long been studied and feature a gradient of increasing substrate degradation from top to bottom
Externí odkaz:
https://doaj.org/article/ea17a3d612a146f085797373a8163800
Autor:
Olga Kunyavskaya, Azat M. Tagirdzhanov, Andrés Mauricio Caraballo-Rodríguez, Louis-Félix Nothias, Pieter C. Dorrestein, Anton Korobeynikov, Hosein Mohimani, Alexey Gurevich
Publikováno v:
Metabolites, Vol 11, Iss 10, p 693 (2021)
Microbial natural products are a major source of bioactive compounds for drug discovery. Among these molecules, nonribosomal peptides (NRPs) represent a diverse class of natural products that include antibiotics, immunosuppressants, and anticancer ag
Externí odkaz:
https://doaj.org/article/41a5b9fd08ee495d855c297620e135eb