Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Louis-Étienne Lorenzo"'
Autor:
Weilai Dong, Sheng Chih Jin, August Allocco, Xue Zeng, Amar H. Sheth, Shreyas Panchagnula, Annie Castonguay, Louis-Étienne Lorenzo, Barira Islam, Geneviève Brindle, Karine Bachand, Jamie Hu, Agata Sularz, Jonathan Gaillard, Jungmin Choi, Ashley Dunbar, Carol Nelson-Williams, Emre Kiziltug, Charuta Gavankar Furey, Sierra Conine, Phan Q. Duy, Adam J. Kundishora, Erin Loring, Boyang Li, Qiongshi Lu, Geyu Zhou, Wei Liu, Xinyue Li, Michael C. Sierant, Shrikant Mane, Christopher Castaldi, Francesc López-Giráldez, James R. Knight, Raymond F. Sekula, Jr., J. Marc Simard, Emad N. Eskandar, Christopher Gottschalk, Jennifer Moliterno, Murat Günel, Jason L. Gerrard, Sulayman Dib-Hajj, Stephen G. Waxman, Fred G. Barker, II, Seth L. Alper, Mohamed Chahine, Shozeb Haider, Yves De Koninck, Richard P. Lifton, Kristopher T. Kahle
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101552- (2020)
Summary: Trigeminal neuralgia (TN) is a common, debilitating neuropathic face pain syndrome often resistant to therapy. The familial clustering of TN cases suggests that genetic factors play a role in disease pathogenesis. However, no unbiased, large
Externí odkaz:
https://doaj.org/article/7d4dc8f9ca434d10935677d5c5a4aeb5
Autor:
Annemarie Dedek, Jian Xu, Louis-Étienne Lorenzo, Antoine G Godin, Chaya M Kandegedara, Geneviève Glavina, Jeffrey A Landrigan, Paul J Lombroso, Yves De Koninck, Eve C Tsai, Michael E Hildebrand
Publikováno v:
Brain : a journal of neurology. 145(3)
The prevalence and severity of many chronic pain syndromes differ across sex, and recent studies have identified differences in immune signalling within spinal nociceptive circuits as a potential mediator. Although it has been proposed that sex-speci
Autor:
Emad N. Eskandar, Charuta G. Furey, Adam J. Kundishora, Sierra B Conine, Geyu Zhou, Shrikant Mane, Shreyas Panchagnula, Kristopher T. Kahle, J. Marc Simard, Jungmin Choi, Murat Gunel, Emre Kiziltug, Jennifer Moliterno, Raymond F. Sekula, Qiongshi Lu, Francesc López-Giráldez, Christopher Gottschalk, Seth L. Alper, Fred G. Barker, Geneviève Brindle, Wei Liu, Weilai Dong, Carol Nelson-Williams, Ashley Dunbar, Shozeb Haider, Jason L. Gerrard, Richard P. Lifton, Mohamed Chahine, Michael C. Sierant, James R. Knight, August A Allocco, Amar H. Sheth, Phan Q. Duy, Boyang Li, Barira Islam, Jonathan Gaillard, Sheng Chih Jin, Christopher Castaldi, Xinyue Li, Stephen G. Waxman, Xue Zeng, Erin Loring, Jamie Hu, Louis Étienne Lorenzo, Yves De Koninck, Sulayman D. Dib-Hajj, Karine Bachand, Annie Castonguay, Agata K Sularz
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101552-(2020)
iScience
iScience
Summary Trigeminal neuralgia (TN) is a common, debilitating neuropathic face pain syndrome often resistant to therapy. The familial clustering of TN cases suggests that genetic factors play a role in disease pathogenesis. However, no unbiased, large-
Autor:
Francesco Ferrini, Jimena Perez-Sanchez, Samuel Ferland, Louis-Etienne Lorenzo, Antoine G. Godin, Isabel Plasencia-Fernandez, Martin Cottet, Annie Castonguay, Feng Wang, Chiara Salio, Nicolas Doyon, Adalberto Merighi, Yves De Koninck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Inhibition in spinal nociceptive pathways is weaker and more labile in lamina I —where thermal input is primarily processed— than in lamina II that encodes predominantly high threshold mechanical input. This explains why noxious thermal input mak
Externí odkaz:
https://doaj.org/article/4ac2ed6526874748a22aff64150835ea
Autor:
Louis-Etienne Lorenzo, Antoine G. Godin, Francesco Ferrini, Karine Bachand, Isabel Plasencia-Fernandez, Simon Labrecque, Alexandre A. Girard, Dominic Boudreau, Irenej Kianicka, Martin Gagnon, Nicolas Doyon, Alfredo Ribeiro-da-Silva, Yves De Koninck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-23 (2020)
Disinhibition in the dorsal horn of the spinal cord may contribute to chronic pain. Here the authors show that, despite a paradoxical increase in α2/α3 subunits of the GABAA receptor in a neuropathic pain model, inhibition eventually fails due to K
Externí odkaz:
https://doaj.org/article/7e8316d0d5b2495c8bdcf34c648c6da7
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Morphine-induced hyperalgesia (MIH) is a severe adverse effect accompanying repeated morphine treatment, causing a paradoxical decrease in nociceptive threshold. Previous reports associated MIH with a decreased expression of the Cl− extrud
Externí odkaz:
https://doaj.org/article/0eca9d636d3343e999ceb6e781d6238c
Autor:
Josiane C.S. Mapplebeck, Louis-Etienne Lorenzo, Kwan Yeop Lee, Cédric Gauthier, Milind M. Muley, Yves De Koninck, Steven A. Prescott, Michael W. Salter
Publikováno v:
Cell Reports, Vol 28, Iss 3, Pp 590-596.e4 (2019)
Summary: The behavioral features of neuropathic pain are not sexually dimorphic despite sex differences in the underlying neuroimmune signaling. This raises questions about whether neural processing is comparably altered. Here, we test whether the K+
Externí odkaz:
https://doaj.org/article/aa631a09ebdc4dbaa0b457019ff02ac8
Autor:
Loïc Binan, Javier Mazzaferri, Karine Choquet, Louis-Etienne Lorenzo, Yu Chang Wang, El Bachir Affar, Yves De Koninck, Jiannis Ragoussis, Claudia L. Kleinman, Santiago Costantino
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Cell labelling in a non-invasive and genetic engineering-free manner is crucial to cell biology applications. Here the authors develop cell labelling via photobleaching (CLaP), that uses laser illumination to label individual cells for genomics, cell
Externí odkaz:
https://doaj.org/article/82b7efadde1744799f964a4dd60168bb