Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Louis T Lotta"'
Autor:
Aaron N. Huynh, AnnaLynn M. Williams, Elizabeth K. Belcher, Paige Van Haute, Louis T. Lotta, Bryan Thompson, Colleen Netherby-Winslow, Amarinthia Curtis, Benjamin T. Esparaz, Carla Jorgensen, Sara Alberti, Emma Bentley, Hongying Sun, Eva Culakova, Michelle C. Janelsins
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 41, Iss , Pp 100860- (2024)
Many patients with cancer experience cancer-related cognitive decline (CRCD). Previous studies have shown that elevated S100β, a calcium-binding protein commonly found in glial cells, can exhibit neurotoxic effects, including disruption of the blood
Externí odkaz:
https://doaj.org/article/a77917e415c14ed6813c9f050e073d76
Autor:
Elizabeth K Belcher, Eva Culakova, Nikesha J Gilmore, Sara J Hardy, Amber S Kleckner, Ian R Kleckner, Lianlian Lei, Charles Heckler, Michael B Sohn, Bryan D Thompson, Louis T Lotta, Zachary A Werner, Jodi Geer, Judith O Hopkins, Steven W Corso, David Q Rich, Edwin van Wijngaarden, Michelle C Janelsins
Publikováno v:
J Natl Cancer Inst
Background Inflammation may contribute to cognitive difficulties in patients with breast cancer. We tested 2 hypotheses: inflammation is elevated in patients with breast cancer vs noncancer control participants and inflammation in patients is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb351a899c9499cd19fccbfe9059d54
https://pubmed.ncbi.nlm.nih.gov/35134984
https://pubmed.ncbi.nlm.nih.gov/35134984
Publikováno v:
Journal of Cancer Research & Therapy, Vol 4, Iss 2, Pp 11-18 (2016)
Journal of cancer research & therapy
Journal of cancer research & therapy
Neuroblastoma, the most frequently occurring extracranial solid tumor of childhood, arises from neural crest-derived cells that are arrested at an early stage of differentiation in the developing sympathetic nervous system. There is an urgent need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6719e4317e1ddc5ab5aa1638e4a29897
https://doi.org/10.14312/2052-4994.2016-3
https://doi.org/10.14312/2052-4994.2016-3
Autor:
Jeanne N. Hansen, Kun Qian, Linda J. Valentijn, Xingguo Li, Emmett Livingstone, Allison Eberhardt, Simeng Wang, Yujun George Zheng, Jan Koster, Louis T. Lotta, Nina F. Schor
Publikováno v:
Oncotarget, 7(39), 63629-63639. Impact Journals
Oncotarget
Oncotarget
// Allison Eberhardt 1 , Jeanne N. Hansen 1 , Jan Koster 2 , Louis T. Lotta Jr. 1 , Simeng Wang 1 , Emmett Livingstone 1 , Kun Qian 3 , Linda J. Valentijn 2 , Yujun George Zheng 3 , Nina F. Schor 1 , Xingguo Li 1 1 Department of Pediatrics, Universit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3948fb6a6f13b1ffcd6ee26ee3a7b472
https://doi.org/10.18632/oncotarget.11556
https://doi.org/10.18632/oncotarget.11556
Publikováno v:
ACS chemical neuroscience. 8(10)
Neuroblastoma is a cancer of the neural crest almost exclusively seen in childhood. While children with single, small primary tumors are often cured with surgery alone, the 65% of children with neuroblastoma whose disease has metastasized have less t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3c2496b8d11155e2c2993280affea5
https://pubmed.ncbi.nlm.nih.gov/28800395
https://pubmed.ncbi.nlm.nih.gov/28800395
Autor:
Yujun George Zheng, Louis T. Lotta, Allison Eberhardt, Nina F. Schor, Jeanne N. Hansen, Sen Ji, Xingguo Li, Shengyong Yang
Publikováno v:
Cancer Research. 78:B22-B22
The MYC family of transcription factors is one of the most frequently overexpressed oncogenes in human malignancies, including tumors that are derived from the nervous system. MYCN plays a causative role in neuroblastoma, a common and fatal childhood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87bea48fd8813de81a4ec0776008583e
https://doi.org/10.1158/1538-7445.pedca17-b22
https://doi.org/10.1158/1538-7445.pedca17-b22
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Fenretinide is a chemotherapeutic agent in clinical trials for the treatment of neuroblastoma, among the most common and most deadly cancers of childhood. Fenretinide induces apoptosis in neuroblastoma cells through accumulation of mitochondrial reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7189b215df1d4f85ebe01aa7dd1797f8
http://europepmc.org/articles/PMC4657150
http://europepmc.org/articles/PMC4657150
Autor:
Zsuzsanna Izsvák, Suresh de Silva, Zoltán Ivics, William J. Bowers, Louis T. Lotta, Clark A. Burris, Michael A. Mastrangelo
The Sleeping Beauty (SB) transposon system has been successfully used as a gene delivery tool in nonviral and viral vector platforms. Since its initial reconstruction, a series of hyperactive mutants of SB have been generated. Questions remain as to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d8d34de1cc3e625de1e29f1e4b4606
https://europepmc.org/articles/PMC2978550/
https://europepmc.org/articles/PMC2978550/
Publikováno v:
Human gene therapy. 21(11)
The development of the integration-competent, herpes simplex virus/Sleeping Beauty (HSV/SB) amplicon vector platform has created a means to efficiently and stably deliver therapeutic transcription units (termed "transgenons") to neurons within the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b4c817811146905c663a6e39a1a1ee
https://pubmed.ncbi.nlm.nih.gov/20568967
https://pubmed.ncbi.nlm.nih.gov/20568967
Autor:
S de Silva, Michael A. Mastrangelo, Howard J. Federoff, Louis T. Lotta, William J. Bowers, Clark A. Burris
The ability of a viral vector to safely deliver and stably integrate large transgene units (transgenons), which not only include one or several therapeutic genes but also requisite native transcriptional regulatory elements, would be of significant b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94a20737154926ba8e958da708fcd41
https://europepmc.org/articles/PMC2837128/
https://europepmc.org/articles/PMC2837128/