Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Louis S. Ramagli"'
Autor:
Yujia Huo, Yue Lu, Jean Pierre J. Issa, David Graber, Steven M. Kornblau, Louis S. Ramagli, Jaroslav Jelinek, Gabriel G. Malouf, Marcos R. Estecio, Jumpei Yamazaki, Shoudan Liang, Hai Long
Publikováno v:
Epigenetics. 8:92-104
Acute myeloid leukemia (AML) is sustained by a population of cancer stem cells (CSCs or cancer-initiating cell). The mechanisms underlying switches from CSCs to non-CSCs in vivo remain to be understood. We address this issue in AML from the aspect of
Autor:
Brian C. Ramagli, Louis S. Ramagli, Barry W. Brown, Patrick M. Lynch, Mary Coolbaugh-Murphy, Marsha L. Frazier, Jing Ping Xu, Stanley R. Hamilton, Michael J. Siciliano
Publikováno v:
Human Mutation. 31:317-324
Most hereditary nonpolyposis colorectal cancer (HNPCC) patients inherit a defective allele of a mismatch repair (MMR) gene, usually MLH1 or MSH2, resulting in high levels of microsatellite instability (MSI-H) in the tumors. Presence of MSI in the nor
Autor:
Tiina Suominen, Michael J. Siciliano, Tomasz J. Czernuszewicz, Linda L. Bachinski, Ralf Krahe, Mark D. Shriver, Louis S. Ramagli, B. Udd
Publikováno v:
Neurology. 72:490-497
Background: The myotonic dystrophies (DM1, DM2) are the most common adult muscle diseases and are characterized by multisystem involvement. DM1 has been described in diverse populations, whereas DM2 seems to occur primarily in European Caucasians. Bo
Publikováno v:
Current Colorectal Cancer Reports. 3:185-190
The contributions and limitations of the traditional method for evaluating microsatellite instability by standard polymerase chain reaction (PCR) in identifying mismatch repair (MMR) gene mutations in the Lynch syndrome form of hereditary nonpolyposi
Publikováno v:
Mechanisms of Ageing and Development. 126:1051-1059
Small pool PCR (SP-PCR) is a sensitive method for the detection and quantification of microsatellite instability (MSI) in somatic cells. Here we propose that mutant microsatellite fragments accumulate with age in normal somatic cells and that this in
Autor:
Carolyn A. Peterson, Gunilla Kanter-Smoler, Lei Li, Michael J. Siciliano, Ying Fei Wei, Randy J. Legerski, Louis S. Ramagli, Per Sunnerhagen
Publikováno v:
Oncogene. 18:1689-1699
The RAD17 gene product of S. Pombe is an essential component of the checkpoint control pathway which responds to both DNA damage and disruption of replication. We have identified a human cDNA that encodes a polypeptide which is structurally conserved
Autor:
Louis S. Ramagli, Evan E. Eichler, Michael J. Siciliano, Harvey W. Mohrenweiser, Thomas C. Wood, Richard M. Weinshilboum, Chengtao Her
Publikováno v:
Genomics. 53:284-295
We have cloned and characterized cDNAs that encode two human hydroxysteroid sulfotransferase (SULT) enzymes, SULT2B1a and SULT2B1b, as well as the single gene that encodes both of these enzymes. The two cDNAs differed at their 5'-termini and had 1050
Autor:
Shoudan Liang, Rong He, Jaroslav Jelinek, Jean Pierre J. Issa, Yue Lu, Louis S. Ramagli, Elizabeth J. Shpall, Marcos R. Estecio
Publikováno v:
Epigenetics. 7(12)
Genome wide analysis of DNA methylation provides important information in a variety of diseases, including cancer. Here, we describe a simple method, Digital Restriction Enzyme Analysis of Methylation (DREAM), based on next generation sequencing anal
Autor:
Lisa V. Tsui, Chuan Gao, Tej K. Pandita, Ralph B. Arlinghaus, Louis S. Ramagli, Chau D. Pham, Balraj Singh
Publikováno v:
International journal of oncology. 11(6)
In order to determine the physiological significance of c-mos RNA expression in somatic cells, we introduced antisense c-mos under the control of an inducible promoter. NIH/3T3 cells were stably transfected with antisense mos under the control of the
Publikováno v:
Journal of Virology. 64:3093-3096
The v-mos protein, termed p37v-mos, has a closely associated serine/threonine protein kinase activity. To provide further information about its protein kinase activity, we tested the activity of p37v-mos produced in a cell-free translation system fro