Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Louis S, Stodieck"'
Autor:
Pin Ha, Jin Hee Kwak, Yulong Zhang, Jiayu Shi, Luan Tran, Timothy Pan Liu, Hsin-Chuan Pan, Samantha Lee, Jong Kil Kim, Eric Chen, Yasaman Shirazi-Fard, Louis S. Stodieck, Andy Lin, Zhong Zheng, Stella Nuo Dong, Xinli Zhang, Benjamin M. Wu, Kang Ting, Chia Soo
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Microgravity-induced bone loss results in a 1% bone mineral density loss monthly and can be a mission critical factor in long-duration spaceflight. Biomolecular therapies with dual osteogenic and anti-resorptive functions are promising for t
Externí odkaz:
https://doaj.org/article/f3f5579d49db42358eb8834e95d4a820
Autor:
Andrea M. Hanson, Mary H. Young, Brooke C. Harrison, Xiaolan Zhou, H. Q. Han, Louis S. Stodieck, Virginia L. Ferguson
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Novel treatments for muscle wasting are of significant value to patients with disease states that result in muscle weakness, injury recovery after immobilization and bed rest, and for astronauts participating in long-duration spaceflight. We
Externí odkaz:
https://doaj.org/article/9312246776294c9ca7f1d9de58b313bf
Autor:
Andy T. Kwok, Nequesha S. Mohamed, Johannes F. Plate, Raghunatha R. Yammani, Samuel Rosas, Ted A. Bateman, Eric Livingston, Joseph E. Moore, Bethany A. Kerr, Jingyun Lee, Cristina M. Furdui, Li Tan, Mary L. Bouxsein, Virginia L. Ferguson, Louis S. Stodieck, David C. Zawieja, Michael D. Delp, Xiao W. Mao, Jeffrey S. Willey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Reduced knee weight-bearing from prescription or sedentary lifestyles are associated with cartilage degradation; effects on the meniscus are unclear. Rodents exposed to spaceflight or hind limb unloading (HLU) represent unique opportunities
Externí odkaz:
https://doaj.org/article/e20ccc74580a4e1287b71ce54f1f7858
Autor:
Alexa Wnorowski, Arun Sharma, Haodong Chen, Haodi Wu, Ning-Yi Shao, Nazish Sayed, Chun Liu, Stefanie Countryman, Louis S. Stodieck, Kathleen H. Rubins, Sean M. Wu, Peter H.U. Lee, Joseph C. Wu
Publikováno v:
Stem Cell Reports, Vol 13, Iss 6, Pp 960-969 (2019)
Summary: With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocyt
Externí odkaz:
https://doaj.org/article/1a462e3bc42446aa949cd8d4fa18e096
Autor:
Samuel M. Cadena, Yunyu Zhang, Jian Fang, Sophie Brachat, Pia Kuss, Elisa Giorgetti, Louis S. Stodieck, Michaela Kneissel, David J. Glass
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Microgravity exposure is associated with loss of muscle mass and strength. The E3 ubiquitin ligase MuRF1 plays an integral role in degrading the contractile apparatus of skeletal muscle; MuRF1 null (KO) mice have shown protection in ground-b
Externí odkaz:
https://doaj.org/article/38bd92eb66384209bb03539a66816b7a
Autor:
Jennifer C. Coulombe, Zachary K. Mullen, Maureen E. Lynch, Louis S. Stodieck, Virginia L. Ferguson
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101497- (2021)
The current standard approach for analyzing cortical bone structure and trabecular bone microarchitecture from micro-computed tomography (microCT) is through classic parametric (e.g., ANOVA, Student's T-test) and nonparametric (e.g., Mann-Whitney U t
Externí odkaz:
https://doaj.org/article/016269be6538448eb453c2135fbef3e0
Autor:
Rosamund C Smith, Martin S Cramer, Pamela J Mitchell, Jonathan Lucchesi, Alicia M Ortega, Eric W Livingston, Darryl Ballard, Ling Zhang, Jeff Hanson, Kenneth Barton, Shawn Berens, Kelly M Credille, Ted A Bateman, Virginia L Ferguson, Yanfei L Ma, Louis S Stodieck
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230818 (2020)
The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice w
Externí odkaz:
https://doaj.org/article/decc66a177f0408f8026fd6a168de5b9
Autor:
Michael J Pecaut, Xiao Wen Mao, Denise L Bellinger, Karen R Jonscher, Louis S Stodieck, Virginia L Ferguson, Ted A Bateman, Robert P Mohney, Daila S Gridley
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0174174 (2017)
The Space Shuttle Atlantis launched on its final mission (STS-135) on July 8, 2011. After just under 13 days, the shuttle landed safely at Kennedy Space Center (KSC) for the last time. Female C57BL/6J mice flew as part of the Commercial Biomedical Te
Externí odkaz:
https://doaj.org/article/4dd5a5e13d5e47a280907faaca132817
Autor:
Karen R Jonscher, Alba Alfonso-Garcia, Jeffrey L Suhalim, David J Orlicky, Eric O Potma, Virginia L Ferguson, Mary L Bouxsein, Ted A Bateman, Louis S Stodieck, Moshe Levi, Jacob E Friedman, Daila S Gridley, Michael J Pecaut
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152877 (2016)
Spaceflight affects numerous organ systems in the body, leading to metabolic dysfunction that may have long-term consequences. Microgravity-induced alterations in liver metabolism, particularly with respect to lipids, remain largely unexplored. Here
Externí odkaz:
https://doaj.org/article/7c422ce289b240308143a4b00e509f57
Autor:
Karen R Jonscher, Alba Alfonso-Garcia, Jeffrey L Suhalim, David J Orlicky, Eric O Potma, Virginia L Ferguson, Mary L Bouxsein, Ted A Bateman, Louis S Stodieck, Moshe Levi, Jacob E Friedman, Daila S Gridley, Michael J Pecaut
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155282 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0152877.].
Externí odkaz:
https://doaj.org/article/e2040aea9eb74ed2a5b51b4b2ca68c78