Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Louis R Hollingsworth"'
Autor:
Khidir W Hilu, Sheena A Friend, Viruthika Vallanadu, Anne M Brown, Louis R Hollingsworth, David R Bevan
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0222440 (2019)
Food allergies are severe immune responses to plant and animal products mediated by immunoglobulin E (IgE). Peanuts (Arachis hypogaea L.) are among the top 15 crops that feed the world. However, peanuts is among the "big eight food allergens", and al
Externí odkaz:
https://doaj.org/article/e91634d0c7e2433194c3c4ce45ab6148
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190658 (2018)
Multiple approaches are being utilized to develop therapeutics to treat HIV infection. One approach is designed to inhibit entry of HIV into host cells, with a target being the viral envelope glycoprotein, gp120. Polyanionic compounds have been shown
Externí odkaz:
https://doaj.org/article/d22f50555c4045efa5b2ca47a3ae2413
Autor:
Jeffrey C. Hsiao, Louis R. Hollingsworth, Humayun Sharif, Qinghui Wang, Hao Wu, Daniel A. Bachovchin, Andrew R. Griswold
SUMMARYCARD8 is a germline-encoded pattern recognition receptor that detects intracellular danger signals. Like the related inflammasome sensor NLRP1, CARD8 undergoes constitutive autoprocessing within its function-to-find domain (FIIND), generating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eddf07aadee5dba56bcee212d0863f15
https://doi.org/10.1101/2021.01.13.426575
https://doi.org/10.1101/2021.01.13.426575
Autor:
Jianbin Ruan, Liron David, Humayun Sharif, Andrew R. Griswold, Yang Li, Louis R. Hollingsworth, Daniel A. Bachovchin, Hao Wu, Tian-Min Fu, Pietro Fontana
NLRP1 and CARD8 are related cytosolic sensors that upon activation form supramolecular signalling complexes known as canonical inflammasomes, resulting in caspase-1 activation, cytokine maturation and/or pyroptotic cell death. NLRP1 and CARD8 use the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6650e53c822c9fe067da22f56d9a2fd
https://doi.org/10.1101/2020.06.27.175497
https://doi.org/10.1101/2020.06.27.175497
Autor:
Louis R. Hollingsworth
Protocol associated with "DPP9 sequesters the NLRP1 C-terminus to repress inflammasome activation" by Hollingsworth*, Sharif*, Griswold* et al., Bachovchin, and Wu. Please address any questions to Bobby Hollingsworth (bobbyh11@vt.edu). General Expi29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::365a6fee51a9e7469e9bea8dacc57cad
https://doi.org/10.17504/protocols.io.833hyqn
https://doi.org/10.17504/protocols.io.833hyqn
Autor:
Louis R. Hollingsworth
Protocol associated with "DPP9 sequesters the NLRP1 C-terminus to repress inflammasome activation" by Hollingsworth*, Sharif*, Griswold* et al., Bachovchin, and Wu. Please address any questions to Bobby Hollingsworth (bobbyh11@vt.edu).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff72b4472d4bc8d90a3fd920a3c8a194
https://doi.org/10.17504/protocols.io.84ihyue
https://doi.org/10.17504/protocols.io.84ihyue
Publikováno v:
PLoS ONE
Multiple approaches are being utilized to develop therapeutics to treat HIV infection. One approach is designed to inhibit entry of HIV into host cells, with a target being the viral envelope glycoprotein, gp120. Polyanionic compounds have been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4cb75d443810d81d1018a68383992a2
https://pubmed.ncbi.nlm.nih.gov/29346393
https://pubmed.ncbi.nlm.nih.gov/29346393
Publikováno v:
PEARC
Computational tools and techniques are attractive due to the low-cost and scope of application and are becoming more prevalent and accepted across a variety of fields. With the advancement of high performance computing resources and the recent utilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c763f5c9da0a6d781cc49b40a9d731b9
https://doi.org/10.1145/3093338.3104154
https://doi.org/10.1145/3093338.3104154
Publikováno v:
Cold Spring Harb Perspect Biol
The innate immune system senses and responds to pathogens and endogenous damage through supramolecular protein complexes known as inflammasomes. Cytosolic inflammasome sensor proteins trigger inflammasome assembly on detection of infection and danger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80556378aaebf64c8b6ebf50acbe52eb
https://doi.org/10.1101/cshperspect.a036400
https://doi.org/10.1101/cshperspect.a036400
Publikováno v:
Biophysical Journal. 116:46a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86d77ba0f312637140b8d71953ceab8a
https://doi.org/10.1016/j.bpj.2018.11.293
https://doi.org/10.1016/j.bpj.2018.11.293