Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Louis M. Tsai"'
Autor:
Robert Brink, Charles R. Mackay, Di Yu, Jian Tan, Louis M. Tsai, Katherine Bourne, Alison N. Thorburn, Remy Robert, Linda J. Mason, Nina Chevalier, Connie H.Y. Wong, Laurence Macia
Publikováno v:
Arthritis & Rheumatology. 68:1026-1038
ObjectiveAntibody-mediated autoimmunity involves cognate interactions between self-reactive T cells and B cells during germinal center (GC) reactions. The aim of this study was to determine the role of essential follicular helper T (Tfh) cell molecul
Autor:
Louis M. Tsai, Di Yu
Publikováno v:
Immunology & Cell Biology. 92:57-63
The generation of immunological memory during an immune response is a hallmark of the adaptive immune system. Follicular helper T (Tfh) cells are a CD4(+) T-cell subset specialised to regulate antibody response. Emerging evidence suggests that during
Autor:
André Veillette, Steve Rockman, Sean Riminton, Alexander Karnowski, Matthew C. Cook, Cindy S. Ma, Carola G. Vinuesa, Stuart G. Tangye, Changqi Wang, Yew Ann Leong, Fabienne Mackay, Lei Zhu, Charles R. Mackay, Wei Wei, Zhanguo Li, Xin Jack Hu, Yan Ding, Kirsten Vandenberg, Joanna R. Ghali, Gabrielle T. Belz, Robert Brink, Di Yu, Jing He, Louis M Tsai, Nina Chevalier, Xiaolin Sun, Pamela L. Schwartzberg
Publikováno v:
Immunity. 39:770-781
Follicular B helper T (Tfh) cells support high affinity and long-term antibody responses. Here we found that within circulating CXCR5(+) CD4(+) T cells in humans and mice, the CCR7(lo)PD-1(hi) subset has a partial Tfh effector phenotype, whereas CCR7
Autor:
Sidonia Fagarasan, Robert J. Rigby, Roybel R. Ramiscal, Jennifer L. Marshall, Tyani D. Chan, Dimitra Zotos, Adam F. Cunningham, Louis M. Tsai, Sau K. Lee, David M. Tarlinton, Carola G. Vinuesa, Di Yu, Shimpei Kawamoto, Robert Brink, Dominique Gatto
Publikováno v:
The Journal of Experimental Medicine
Bcl-6 expression in CD4+ T cells is required to generate extrafollicular antibody responses.
T follicular helper cells (Tfh cells) localize to follicles where they provide growth and selection signals to mutated germinal center (GC) B cells, thu
T follicular helper cells (Tfh cells) localize to follicles where they provide growth and selection signals to mutated germinal center (GC) B cells, thu
Autor:
Nina, Chevalier, Laurence, Macia, Jian K, Tan, Linda J, Mason, Remy, Robert, Alison N, Thorburn, Connie H Y, Wong, Louis M, Tsai, Katherine, Bourne, Robert, Brink, Di, Yu, Charles R, Mackay
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 68(4)
Antibody-mediated autoimmunity involves cognate interactions between self-reactive T cells and B cells during germinal center (GC) reactions. The aim of this study was to determine the role of essential follicular helper T (Tfh) cell molecules (CXCR5
Autor:
Suzanne M. Crowe, Clovis S. Palmer, Maelenn Gouillou, Alan L. Landay, Lewin, Matias Ostrowski, Anna C. Hearps, Jingling Zhou, Di Yu, Louis M. Tsai, Anthony Jaworowski, Joseph M. McCune, Anna Maisa, Darren C. Henstridge
Publikováno v:
AIDS (London, England), vol 28, iss 3
Objectives: Glucose metabolism plays a fundamental role in supporting the growth, proliferation and effector functions of T cells. We investigated the impact of HIV infection on key processes that regulate glucose uptake and metabolism in primary CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ab18dc9e1265beef5e93d72d303174
https://escholarship.org/uc/item/6zd6152h
https://escholarship.org/uc/item/6zd6152h
Publikováno v:
Annals of the rheumatic diseases. 69
MicroRNA (miRNA), a group of short non-coding RNA of approximately 20-22 nucleotides modulating the stability and translational efficiency of target messenger RNA, present an important new layer controlling gene expression. Hundreds to a thousand miR
Autor:
Di Yu, Louis M. Tsai
Publikováno v:
Clinical and experimental pharmacologyphysiology. 37(1)
1. Evidence gathered in recent years has revealed microRNAs (miRNAs) fine-tune gene expression and play an important role in various cellular processes, including cell growth, differentiation, proliferation and apoptosis. 2. The present review summar
Autor:
Charles R. Mackay, Julia I. Ellyard, Sau K. Lee, Christopher R. Parish, Louis M. Tsai, Lei Zheng, Yiqing He, Ian A. Parish, Nicholas Simpson, Qi-Jing Li, Di Yu, Mnika Srivastava, Sudha Rao, Elissa L Sutcliffe, Carola G. Vinuesa, Cindy S. Ma, Michelle A. Linterman
Publikováno v:
Immunity. (3):457-468
Follicular helper T (Tfh) cells provide selection signals to germinal center B cells, which is essential for long-lived antibody responses. High CXCR5 and low CCR7 expression facilitates their homing to B cell follicles and distinguishes them from T