Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Louis M Mansky"'
Publikováno v:
Therapeutics and Clinical Risk Management, Vol 2010, Iss default, Pp 41-47 (2009)
Iwen F Grigsby1,2,3,4,5, Lan Pham1,2,4, Louis M Mansky3,4,5, Raj Gopalakrishnan3,4, Kim C Mansky1,2,41Division of Orthodontics, 2Department of Developmental and Surgical Sciences, 3Department of Diagnostic and Biological Sciences, 4MinnCResT Program,
Externí odkaz:
https://doaj.org/article/90367105684c41e7bd82638e58bdbd7e
Publikováno v:
Viruses, Vol 16, Iss 10, p 1528 (2024)
Retroviral assembly is a highly coordinated step in the replication cycle. The process is initiated when the newly synthesized Gag and Gag-Pol polyproteins are directed to the inner leaflet of the plasma membrane (PM), where they facilitate the buddi
Externí odkaz:
https://doaj.org/article/6663d27acbec419dabdff82fc0198a14
Autor:
Christine L Clouser, Colleen M Holtz, Mary Mullett, Duane L Crankshaw, Jacquie E Briggs, Jay Chauhan, Ilze Matise VanHoutan, Steven E Patterson, Louis M Mansky
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15840 (2011)
Replication of retroviral and host genomes requires ribonucleotide reductase to convert rNTPs to dNTPs, which are then used as substrates for DNA synthesis. Inhibition of ribonucleotide reductase by hydroxyurea (HU) has been previously used to treat
Externí odkaz:
https://doaj.org/article/f026ad58c462443f84cd468dd8c82893
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/45d6f74a3f9b474d94322cc2a782a38b
HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation
Autor:
Nathaniel Talledge, Huixin Yang, Ke Shi, Raffaele Coray, Guichuan Yu, William G. Arndt, Shuyu Meng, Gloria C. Baxter, Luiza M. Mendonça, Daniel Castaño-Díez, Hideki Aihara, Louis M. Mansky, Wei Zhang
Publikováno v:
Journal of Molecular Biology. 435:168143
Retrovirus immature particle morphology consists of a membrane enclosed, pleomorphic, spherical and incomplete lattice of Gag hexamers. Previously, we demonstrated that human immunodeficiency virus type 2 (HIV-2) immature particles possess a distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cb95be03f1d1fe8d891293370af43d
https://doi.org/10.1016/j.jmb.2023.168143
https://doi.org/10.1016/j.jmb.2023.168143
Publikováno v:
Viruses. 14(5)
Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles. Retroviral RNA packaging requires RNA export of the unspliced genomic RNA from the nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907d307e73bd9bc4d8941e16d588268d
https://pubmed.ncbi.nlm.nih.gov/35632835
https://pubmed.ncbi.nlm.nih.gov/35632835
Autor:
Madison B. Adolph, Robin P. Love, Nazanin Mohammadzadeh, Linda Chelico, Louis M. Mansky, Yumeng Z McDaniel, Dake Wang
Publikováno v:
Nucleic Acids Research
The human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3, A3) family member proteins can deaminate cytosines in single-strand (ss) DNA, which restricts human immunodeficiency virus type 1 (HIV-1), retrotransposons, and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9672ab12e554dab6beb84f49d5cceda5
http://europepmc.org/articles/PMC7026630
http://europepmc.org/articles/PMC7026630
Autor:
Dominik Herrmann, Heather M. Hanson, Lynne W. Zhou, Rayna Addabbo, Nora A. Willkomm, Isaac Angert, Joachim D. Mueller, Louis M. Mansky, Jamil S. Saad
Publikováno v:
Journal of molecular biology. 434(12)
Assembly of human T-cell leukemia virus type 1 (HTLV-1) particles is initiated by the trafficking of virally encoded Gag polyproteins to the inner leaflet of the plasma membrane (PM). Gag-PM interactions are mediated by the matrix (MA) domain, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59687451cfeebab826065a4fb27b08d5
https://pubmed.ncbi.nlm.nih.gov/35490898
https://pubmed.ncbi.nlm.nih.gov/35490898
The cell cortex plays a crucial role in cell mechanics, signaling, and development. However, little is known about the influence of the cortical meshwork on the spatial distribution of cytoplasmic biomolecules. Here, we describe a new fluorescence mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9892b5e2a5086f8c1365cb80893f07d1
https://doi.org/10.1101/2021.10.01.462753
https://doi.org/10.1101/2021.10.01.462753
Autor:
William G. Arndt, Lauren J. Mills, Louis M. Mansky, Emily Julik, Morgan E. Meissner, Jonathan P. Badalamenti
Publikováno v:
Viruses
Viruses, Vol 13, Iss 1338, p 1338 (2021)
Volume 13
Issue 7
Viruses, Vol 13, Iss 1338, p 1338 (2021)
Volume 13
Issue 7
Human immunodeficiency virus type 2 (HIV-2) accumulates fewer mutations during replication than HIV type 1 (HIV-1). Advanced studies of HIV-2 mutagenesis, however, have historically been confounded by high background error rates in traditional next-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65eccad4a8737f56a3b2e6f0f1bb7814
http://europepmc.org/articles/PMC8310143
http://europepmc.org/articles/PMC8310143