New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Autor: Anne-Claire Vergnaud, Tibor V. Varga, Melissa A. Richard, Jaakko Tuomilehto, Louise V. Wain, Leif Groop, Reedik Mägi, Danish Saleheen, Olle Melander, Marcus Dörr, He Zhang, Alena Stančáková, Michael Boehnke, Claudia Langenberg, Paul Elliott, Adam S. Butterworth, Andrianos M. Yiorkas, Yingchang Lu, Tea Skaaby, George Dedoussis, Xiuqing Guo, Robin Young, Cristiano Fava, Timo A. Lakka, Igor Rudan, Riccardo E. Marioni, Helen R. Warren, Ioanna Tzoulaki, Myriam Fornage, Bruce M. Psaty, Tõnu Esko, Najaf Amin, Vilmundur Gudnason, Ozren Polasek, Yongmei Liu, Panos Deloukas, Paul M. Ridker, Vinicius Tragante, John M. C. Connell, Mark J. Caulfield, Jette Bork-Jensen, Giovanni Malerba, Eric Boerwinkle, Alanna C. Morrison, Todd L. Edwards, Teresa Ferreira, Torben Hansen, Aldi T. Kraja, He Gao, Alaitz Poveda, Praveen Surendran, Christopher Newton-Cheh, Christian Theil Have, Cramer Christensen, Daniel I. Chasman, Paul W. Franks, Ian J. Deary, Xueling Sim, Evangelos Evangelou, Roby Joehanes, Daniel R. Witte, Cristina Menni, Niels Grarup, Weihua Zhang, Eleftheria Zeggini, Anubha Mahajan, Nora Franceschini, Fredrik Karpe, Lars Lind, Rainer Rauramaa, Oluf Pedersen, Pim van der Harst, Jeanette M. Stafford, Alisa K. Manning, Lori L. Bonnycastle, Rudolf A. de Boer, Kenneth Rice, Nicholas J. Wareham, Tiinamaija Tuomi, Charles Kooperberg, Alexandra I. F. Blakemore, Kathleen Stirrups, Marjo-Riitta Järvelin, Michael A. Province, Marit E. Jørgensen, Allan Linneberg, Veikko Salomaa, Albert V. Smith, Cornelia M. van Duijn, Hao Mei, Mark I. McCarthy, Nilesh J. Samani, Anna F. Dominiczak, Joanna M. M. Howson, Erik Ingelsson, Colin N. A. Palmer, Markku Laakso, Karen L. Mohlke, Folkert W. Asselbergs, Sarah E. Harris, Ayush Giri, Daniel Levy, Anne Mari Käräjämäki, Michael R. Barnes, Aliki-Eleni Farmaki, Muhammad Riaz, Lorraine Southam, Karl-Heinz Herzig, Caroline Hayward, Nigel W. Rayner, John Danesh, Ruth J. F. Loos, Jennifer A. Smith, Ivan Brandslund, Neil Poulter, Jerome I. Rotter, Peter S. Sever, Chunyu Liu, John M. Starr, Stefan Weiss, Georg Ehret, Cecilia M. Lindgren, Walter Palmas, Fotios Drenos, Jaspal S. Kooner, Göran Hallmans, Megan L. Grove, Patricia B. Munroe, Andrew P. Morris, Aki S. Havulinna, James P. Cook, John C. Chambers, Cristen J. Willer, Claudia P. Cabrera, Sharon L.R. Kardia, Peter van der Meer, James G. Wilson, Louis Little, Sandosh Padmanabhan, Oksa Heikki, Franco Giulianini, Giovanni Gambaro

Publikováno v: Circulation-Cardiovascular Genetics, 10(5):001778. LIPPINCOTT WILLIAMS & WILKINS
Circulation: Cardiovascular Genetics, Vol. 10, No 5 (2017) P. e001778
Kraja, A T, Cook, J P, Warren, H R, Surendran, P, Liu, C, Evangelou, E, Manning, A K, Grarup, N, Drenos, F, Sim, X, Smith, A V, Amin, N, Blakemore, A I F, Bork-Jensen, J, Brandslund, I, Farmaki, A-E, Fava, C, Ferreira, T, Herzig, K-H, Giri, A, Giulianini, F, Grove, M L, Guo, X, Harris, S E, Have, C T, Havulinna, A S, Zhang, H, Jørgensen, M E, Käräjämäki, A, Kooperberg, C, Linneberg, A, Little, L, Liu, Y, Bonnycastle, L L, Lu, Y, Mägi, R, Mahajan, A, Malerba, G, Marioni, R E, Mei, H, Menni, C, Morrison, A C, Padmanabhan, S, Palmas, W, Poveda, A, Rauramaa, R, Rayner, N W, Riaz, M, Christensen, C K, Hansen, T & Understanding Society Scientific Group 2017, ' New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals ', Circulation: Cardiovascular Genetics, vol. 10, no. 5, e001778 . https://doi.org/10.1161/CIRCGENETICS.117.001778
Circulation-cardiovascular genetics, 10(5):UNSP e001778. Lippincott Williams & Wilkins
Circulation-Cardiovascular genetics, 10(5). Lippincott Williams and Wilkins
CIRCULATION-CARDIOVASCULAR GENETICS
Kraja, A T, Cook, J P, Warren, H R, Surendran, P, Liu, C, Evangelou, E, Manning, A K, Grarup, N, Drenos, F, Sim, X, Smith, A V, Amin, N, Blakemore, A I F, Bork-jensen, J, Brandslund, I, Farmaki, A, Fava, C, Ferreira, T, Herzig, K, Giri, A, Giulianini, F, Grove, M L, Guo, X, Harris, S E, Have, C T, Havulinna, A S, Zhang, H, Jørgensen, M E, Käräjämäki, A, Kooperberg, C, Linneberg, A, Little, L, Liu, Y, Bonnycastle, L L, Lu, Y, Mägi, R, Mahajan, A, Malerba, G, Marioni, R E, Mei, H, Menni, C, Morrison, A C, Padmanabhan, S, Palmas, W, Poveda, A, Rauramaa, R, Rayner, N W, Riaz, M, Richard, M A, Smith, J A, Southam, L, Stančáková, A, Stirrups, K E, Tragante, V, Tuomi, T, Tzoulaki, I, Varga, T V, Weiss, S, Yiorkas, A M, Young, R, Zhang, W, Barnes, M R, Cabrera, C P, Gao, H, Boehnke, M, Boerwinkle, E, Chambers, J C, Connell, J M, Christensen, C K, De Boer, R A, Deary, I J, Dedoussis, G, Deloukas, P, Dominiczak, A F, Dörr, M, Joehanes, R, Edwards, T L, Esko, T, Fornage, M, Franceschini, N, Franks, P W, Gambaro, G, Groop, L, Hallmans, G, Hansen, T, Hayward, C, Heikki, O, Ingelsson, E, Tuomilehto, J, Jarvelin, M, Kardia, S L R, Karpe, F, Kooner, J S, Lakka, T A, Langenberg, C, Lind, L, Loos, R J F, Laakso, M, Mccarthy, M I, Melander, O, Mohlke, K L, Morris, A P, Palmer, C N A, Pedersen, O, Polasek, O, Poulter, N R, Province, M A, Psaty, B M, Ridker, P M, Rotter, J I, Rudan, I, Salomaa, V, Samani, N J, Sever, P J, Skaaby, T, Stafford, J M, Starr, J M, Van Der Harst, P, Van Der Meer, P, Van Duijn, C M, Vergnaud, A, Gudnason, V, Wareham, N J, Wilson, J G, Willer, C J, Witte, D R, Zeggini, E, Saleheen, D, Butterworth, A S, Danesh, J, Asselbergs, F W, Wain, L V, Ehret, G B, Chasman, D I, Caulfield, M J, Elliott, P, Lindgren, C M, Levy, D, Newton-cheh, C, Munroe, P B & Howson, J M M 2017, ' New blood pressure–associated loci Identified in meta-analyses of 475 000 individuals ', Circulation: Cardiovascular Genetics, vol. 10, no. 5, pp. e001778 . https://doi.org/10.1161/CIRCGENETICS.117.001778
Grarup, N, Jørgensen, M E, Pedersen, O, Witte, D R & Understanding Society Scientific Group 2017, ' New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals ', Circulation: Cardiovascular Genetics, vol. 10, no. 5, e001778 . https://doi.org/10.1161/CIRCGENETICS.117.001778

Background— Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants (SNVs) associated with B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00d3d9a2c7fc810727b3a16ce55974e
https://pubmed.ncbi.nlm.nih.gov/29030405

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