Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Louis Lambrechts"'
Autor:
Charlotte Lefèvre, Georgia M. Cook, Adam M. Dinan, Shiho Torii, Hazel Stewart, George Gibbons, Alex S. Nicholson, Liliana Echavarría-Consuegra, Luke W. Meredith, Valeria Lulla, Naomi McGovern, Julia C. Kenyon, Ian Goodfellow, Janet E. Deane, Stephen C. Graham, András Lakatos, Louis Lambrechts, Ian Brierley, Nerea Irigoyen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Zika virus (ZIKV), an emerging mosquito-borne flavivirus, is associated with congenital neurological complications. Here, we investigate potential pathological correlates of virus gene expression in representative ZIKV strains through RNA se
Externí odkaz:
https://doaj.org/article/2dc4a2034fc449a8bca35da7cbd3b0c0
Autor:
Stéphanie Dabo, Annabelle Henrion-Lacritick, Alicia Lecuyer, Davy Jiolle, Christophe Paupy, Diego Ayala, Silvânia da Veiga Leal, Athanase Badolo, Anubis Vega-Rúa, Massamba Sylla, Jewelna Akorli, Sampson Otoo, Joel Lutomiah, Rosemary Sang, John-Paul Mutebi, Maria-Carla Saleh, Noah H Rose, Carolyn S McBride, Louis Lambrechts
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 3, p e0011862 (2024)
African populations of the mosquito Aedes aegypti are usually considered less susceptible to infection by human-pathogenic flaviviruses than globally invasive populations found outside Africa. Although this contrast has been well documented for Zika
Externí odkaz:
https://doaj.org/article/887770f33d474eec85dd8da7c51b7489
Autor:
Rinyaporn Phengchat, Phonchanan Pakparnich, Chatpong Pethrak, Jutharat Pengon, Channarong Sartsanga, Nunya Chotiwan, Kwanchanok Uppakara, Kittitat Suksirisawat, Louis Lambrechts, Natapong Jupatanakul
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTDespite numerous studies highlighting the higher transmissibility of the African Zika virus (ZIKV) lineage compared to the Asian lineage in mosquito vectors, little is known about how the viruses interact with different tissues during the ear
Externí odkaz:
https://doaj.org/article/7290216134694ebc9f013f99866f0ead
Autor:
Louis Lambrechts, Robert C Reiner, M Veronica Briesemeister, Patricia Barrera, Kanya C Long, William H Elson, Alfonso Vizcarra, Helvio Astete, Isabel Bazan, Crystyan Siles, Stalin Vilcarromero, Mariana Leguia, Anna B Kawiecki, T Alex Perkins, Alun L Lloyd, Lance A Waller, Uriel Kitron, Sarah A Jenkins, Robert D Hontz, Wesley R Campbell, Lauren B Carrington, Cameron P Simmons, J Sonia Ampuero, Gisella Vasquez, John P Elder, Valerie A Paz-Soldan, Gonzalo M Vazquez-Prokopec, Alan L Rothman, Christopher M Barker, Thomas W Scott, Amy C Morrison
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011593 (2023)
Dengue virus (DENV) transmission from humans to mosquitoes is a poorly documented, but critical component of DENV epidemiology. Magnitude of viremia is the primary determinant of successful human-to-mosquito DENV transmission. People with the same le
Externí odkaz:
https://doaj.org/article/fef72510ea194d4f8ba41bcc397acb54
Autor:
Sarah Hélène Merkling, Anna Beth Crist, Annabelle Henrion-Lacritick, Lionel Frangeul, Elodie Couderc, Valérie Gausson, Hervé Blanc, Alexander Bergman, Artem Baidaliuk, Ottavia Romoli, Maria-Carla Saleh, Louis Lambrechts
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112977- (2023)
Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective
Externí odkaz:
https://doaj.org/article/da8ffcb0433d472c8580bd85e6fbf99e
Autor:
Amy C Morrison, Valerie A Paz-Soldan, Gonzalo M Vazquez-Prokopec, Louis Lambrechts, William H Elson, Patricia Barrera, Helvio Astete, Veronica Briesemeister, Mariana Leguia, Sarah A Jenkins, Kanya C Long, Anna B Kawiecki, Robert C Reiner, T Alex Perkins, Alun L Lloyd, Lance A Waller, Robert D Hontz, Steven T Stoddard, Christopher M Barker, Uriel Kitron, John P Elder, Alan L Rothman, Thomas W Scott, Proyecto Dengue Group
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0273798 (2023)
Current knowledge of dengue virus (DENV) transmission provides only a partial understanding of a complex and dynamic system yielding a public health track record that has more failures than successes. An important part of the problem is that the foun
Externí odkaz:
https://doaj.org/article/19c7fcc7b67843f98bd361bba84e077b
Autor:
Noah H Rose, Stéphanie Dabo, Silvânia da Veiga Leal, Massamba Sylla, Cheikh T Diagne, Oumar Faye, Ousmane Faye, Amadou A Sall, Carolyn S McBride, Louis Lambrechts
Publikováno v:
PLoS Biology, Vol 20, Iss 10, p e3001864 (2022)
The explosive emergence of Zika virus (ZIKV) across the Pacific and Americas since 2007 was associated with hundreds of thousands of human cases and severe outcomes, including congenital microcephaly caused by ZIKV infection during pregnancy. Althoug
Externí odkaz:
https://doaj.org/article/4d0ce6316004468faaecb79dc16c8b2f
Autor:
Fabien Aubry, Sofie Jacobs, Maïlis Darmuzey, Sebastian Lequime, Leen Delang, Albin Fontaine, Natapong Jupatanakul, Elliott F. Miot, Stéphanie Dabo, Caroline Manet, Xavier Montagutelli, Artem Baidaliuk, Fabiana Gámbaro, Etienne Simon-Lorière, Maxime Gilsoul, Claudia M. Romero-Vivas, Van-Mai Cao-Lormeau, Richard G. Jarman, Cheikh T. Diagne, Oumar Faye, Ousmane Faye, Amadou A. Sall, Johan Neyts, Laurent Nguyen, Suzanne J. F. Kaptein, Louis Lambrechts
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Here, the authors compare seven low passage Zika virus (ZIKV) strains representing the recently circulating viral genetic diversity of African and Asian strains and find that African ZIKV strains have higher transmissibility in mosquitoes and higher
Externí odkaz:
https://doaj.org/article/c48f91d15fcb42c39e43fb6ac7859613
Autor:
Olivia O’Connor, Tey Putita Ou, Fabien Aubry, Stéphanie Dabo, Sylvie Russet, Dominique Girault, Saraden In, Marine Minier, Sebastian Lequime, Thavry Hoem, Sébastien Boyer, Philippe Dussart, Nicolas Pocquet, Valérie Burtet-Sarramegna, Louis Lambrechts, Veasna Duong, Myrielle Dupont-Rouzeyrol
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1346-1357 (2021)
Dengue virus (DENV) evolutionary dynamics are characterized by frequent DENV genotype/lineage replacements, potentially associated with changes in disease severity and human immunity. New Caledonia (NC) and Cambodia, two contrasted epidemiological se
Externí odkaz:
https://doaj.org/article/fafe4a74c9e34e339d6459d5f4befed5
Autor:
Rommel J Gestuveo, Rhys Parry, Laura B Dickson, Sebastian Lequime, Vattipally B Sreenu, Matthew J Arnold, Alexander A Khromykh, Esther Schnettler, Louis Lambrechts, Margus Varjak, Alain Kohl
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010202 (2022)
The exogenous small interfering RNA (exo-siRNA) pathway is a key antiviral mechanism in the Aedes aegypti mosquito, a widely distributed vector of human-pathogenic arboviruses. This pathway is induced by virus-derived double-stranded RNAs (dsRNA) tha
Externí odkaz:
https://doaj.org/article/41a89ffe5db141d2b8a4ce811fe4b539