Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Louis J. Ravin"'
Publikováno v:
Journal of Pharmaceutical Sciences. 68:1369-1374
The degradation kinetics of a new cephalosporin derivative (1) in aqueous solution were investigated at 60 degrees, mu = 0.05, at pH 2.0-10.0. The observed degradation rates followed pseudo-first-order kinetics and were influenced significantly by H2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08f808bb79aec187f79b76ba0579165
https://doi.org/10.1002/jps.2600681108
https://doi.org/10.1002/jps.2600681108
Publikováno v:
International Journal of Pharmaceutics. 26:123-132
Two forms of auranofin, designated as A and B, have been identified. These two forms are identical in composition and differ only in their crystalline morphology. Contrary to usual expectations, form A, having the lower melting temperature, also has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614d247421f8b19de9909dbb1fa017f6
https://doi.org/10.1016/0378-5173(85)90205-4
https://doi.org/10.1016/0378-5173(85)90205-4
Autor:
Rosita Krupinski-olsen, Louis J. Ravin, C. M. Dicken, Cynthia S. Randall, Natarajan Rajagopalan
Publikováno v:
Drug Development and Industrial Pharmacy. 15:489-497
The apparent solubility of S K & F 103829 (2, 3, 4, 5-Tetrahydro- 8-(methyl sulfonyl)-lH-3-benzazepin-7-0l) as a function of pH was determined in the presence of methane sulfonic,acetic and hydrochloric acids. The mesylate salt of S K & F 103829 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e23e2f4176624119f1ba92ccaf092aa2
https://doi.org/10.3109/03639048909040227
https://doi.org/10.3109/03639048909040227
Publikováno v:
International Journal of Pharmaceutics. 46:223-229
Studies have demonstrated the potential for using N , N -dimethylacetamide (DMA) as a solvent for solubilizing amphotericin B. The addition of sodium deoxycholate (NaDOC) to the DMA further enhanced the solubility of amphotericin B. To complement thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5209488a82c0d86645ba7bad5fb82705
https://doi.org/10.1016/0378-5173(88)90082-8
https://doi.org/10.1016/0378-5173(88)90082-8
Publikováno v:
Journal of Pharmaceutical Sciences. 71:406-409
Data are presented showing that the anomalous dissolution behavior of ticrynafen in simulated intestinal fluid without enzyme is due to the presence of potassium ions in the dissolution medium. Solubility studies indicate that an insoluble 1:1 comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec0e03a577e9c964bc2b6fa085a1539
https://doi.org/10.1002/jps.2600710408
https://doi.org/10.1002/jps.2600710408
Publikováno v:
Experimental Biology and Medicine. 141:467-474
SummarySK&F 40491, a triazinoindole, provided antiviral activity when administered intranasally to gibbons infected with human rhinovirus type 2. The compound was effective in a multidose regimen either as a 0.02% solution or a 2.5% suspension. The e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6a9a716312861ca11bb11499df0097
https://doi.org/10.3181/00379727-141-36800
https://doi.org/10.3181/00379727-141-36800
Publikováno v:
Journal of Pharmaceutical Sciences. 51:857-860
Carrageenan was degraded with acid to give materials with sulfate contents varying from 5–30%. Antipeptic activities of these materials correlated closely with the sulfate content. Other sulfated polymers such as polyvinyl sulfonate, sulfated rice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d0069ab59e28d27c7123914c73d01c
https://doi.org/10.1002/jps.2600510909
https://doi.org/10.1002/jps.2600510909
Publikováno v:
Journal of Pharmaceutical Sciences. 59:1290-1295
X-ray diffraction, IR spectroscopy, and differential scanning calorimetry data are presented for the identification of two polymorphic forms and a hydrate of SKF however, Form II had a more rapid dissolution rate in the 50% ethanol solution. Dissolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c18da5df23c46f6e7aabafb76a9491
https://doi.org/10.1002/jps.2600590917
https://doi.org/10.1002/jps.2600590917
Publikováno v:
Journal of Pharmaceutical Sciences. 59:547-550
A correlation has been shown to exist between the flow properties of clomacran phosphate powder blends and capsule fill weight variation when an automatic capsule-filling machine is used.A correlation of 0.96 was obtained for the capsule mixes tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be5c16970340c3833bec90dd2df6f5b
https://doi.org/10.1002/jps.2600590423
https://doi.org/10.1002/jps.2600590423
Publikováno v:
Journal of Pharmaceutical Sciences. 58:1242-1245
Polysorbate 80 has been shown to have a significant effect on the solubility of 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride (SK&F 33134-A). Subsequent in vivo studies in bile-cannulated rats with SK&F 33134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f77b6820cb5b501a2a61e36950e2453
https://doi.org/10.1002/jps.2600581018
https://doi.org/10.1002/jps.2600581018