Crystal Structure of a Rearranged Cage Compound, 3-Hydroxy-4-aza-8-oxoheptacyclo [9.4.1.02,10.03,14.04,9.09,13.012,15]tetradecane

Autor: Douglas W. Oliver, Sarel F. Malan, Armand de Vries, Sandra van Dyk, Louis H.A. Prins, Mino R. Caira

Publikováno v: Journal of Chemical Crystallography. 38:705-709

Polycyclic hydrocarbon compounds exhibit a wide variety of biological activities, ranging from antiviral to Parkinson’s disease. Several structures such as the adamantanes have reached clinical status and are used therapeutically to treat, amongst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdc8890415e21cc10edeee83bf679b81
https://doi.org/10.1007/s10870-008-9381-3

List of Contributors

Autor: A. Michael Crider, Abdu Adem, Adel M. Abuzenadah, Ali Jawad, Benjamin P. Repsold, Boris Decourt, Carmen Martínez-Rincón, Daniel Jun, Darrick Pope, David F. Fischer, David William Klaver, Dolores Rodríguez-Martínez, Eric A. Owens, Eugenie Nepovimova, Faizul H. Nasim, Fares Zeidán-Chuliá, Farhan Jalees Ahmad, Farzana L. Ansari, Filip Zemek, Giuseppina Tesco, Gjumrakch Aliev, Iqbal Ahmad, Ismael Ortuño-Soriano, Jacobus P. Petzer, Jacques Joubert, Jan Korabecny, Javed Ahmad, José Cláudio Fonseca Moreira, José L. Pacheco-del-Cerro, Julie Frearson, Kamil Kuca, Kamil Musilek, Karin E. Sandoval, Katarina Spilovska, Kenneth A. Witt, Lara Pacheco-Cuevas, Louis H.A. Prins, Maged M. Henary, Maria Kontoyianni, Marwan Sabbagh, Mauricio Alcolea-Palafox, Michael Cascio, Michael D. Wall, MiMi Macias, Mohamed A. Embaby, Mohammad A. Kamal, Mohammad Zaki Ahmad, Nasimudeen R. Jabir, Nigel H. Grieg, Nighat Sultana, Omar Aziz, Ondrej Soukup, Othman Sulaiman, Paloma Posada-Moreno, Pierfausto Seneci, Raza Murad Ghalib, Rokiah Hashim, Roland W. Bürli, Sarel F. Malan, Sayed Hasan Mehdi, Shams Tabrez, Sohail Akhter, Surendra Reddy Punganuru, Tyler L. Dost, Umer Rashid, Vageesh Revadigar, Vikneswaran Murugaiyah, Zafar Saied Saify, Ziyaur Rahman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cb3e4ebcf1e869a366b4b8ce214dec4
https://doi.org/10.1016/b978-0-12-803959-5.50020-9

Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxide synthase inhibitors

Autor: Sarel F. Malan, Louis H.A. Prins, Jacobus P. Petzer

Publikováno v: Bioorganicmedicinal chemistry. 17(21)

Monoamine oxidase B (MAO-B) and nitric oxide synthase (NOS) have both been implicated in the pathology of neurodegenerative diseases. In an attempt to design dual-target-directed drugs that inhibit both these enzymes, a series of pteridine-2,4-dione

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9196489d94e94c0db8e7f019e9e915
https://pubmed.ncbi.nlm.nih.gov/19804982