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pro vyhledávání: '"Louis F. H. Lam"'
Publikováno v:
Proceedings of the National Academy of Sciences. 76:2979-2983
We have shown that skin fibroblast from patients with cystic fibrosis (CF) and from carriers for CF [heterozygotes (HZ)] consume more O2 than do their controls. When the mitochondrial electron transport inhibitor rotenone was added to the cells, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0241e53c524a13fa694ae0a37c64e931
https://doi.org/10.1073/pnas.76.6.2979
https://doi.org/10.1073/pnas.76.6.2979
Publikováno v:
Science (New York, N.Y.). 203(4386)
Cultured skin fibroblasts from subjects with cystic fibrosis exhibited normal population doubling times in early passages. After about 13 cumulative population doublings, cystic fibrosis lines doubled more slowly than controls and ceased doubling aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52db9ce3a4bb0f4ea5baea76b2c5f509
https://pubmed.ncbi.nlm.nih.gov/424752
https://pubmed.ncbi.nlm.nih.gov/424752
Autor:
Louis F. H. Lam, Burton L. Shapiro
Publikováno v:
Science (New York, N.Y.). 216(4544)
Intracellular calcium increases significantly as human fibroblasts age in culture. The calcium increase occurs 5 to 6 weeks (passages) earlier and is significantly greater in fibroblasts from subjects with cystic fibrosis in comparison with cells fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b6218ff57d85da25511d5ce04d5c36
https://pubmed.ncbi.nlm.nih.gov/7071590
https://pubmed.ncbi.nlm.nih.gov/7071590
Autor:
Louis F. H. Lam, Burton L. Shapiro
Publikováno v:
Life sciences. 24(26)
Tritiated thymidine (3H-TdR) incorporation into DNA of the fibroblasts derived from subjects with cystic fibrosis (CF) and their controls was studied with scintillation counting and autoradiography. 3H-TdR incorporation at 24 hours postseeding was si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fddf59a2c58c0a2cc44e23337f6b1a
https://pubmed.ncbi.nlm.nih.gov/481117
https://pubmed.ncbi.nlm.nih.gov/481117