Comparison of four DNA extraction methods to extract DNA from cigarette butts collected in Lebanon

Autor: Milad Chalhoub, Madona Eid, Hany Kallassy, Issam Mansour, Louis El Khoury

Publikováno v: Science & Justice. 59:162-165

Cigarette butts collected from crime scenes represent valuable sources of DNA. However the extraction of the genetic material may deem challenging especially when different contaminants may compromise the integrity, quality, and quantity of DNA obtai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12a4f6aa7c34091b7462aee4f6e5f2cc
https://doi.org/10.1016/j.scijus.2018.09.003

Methods to study exercise and sports epigenetics

Autor: Louis El Khoury

Exercise and sports are known to be correlated with positive health outcomes such as increased cardiac output, increased muscle mass, and reduced risk of chronic diseases. Although genetic factors will play a role in these traits, we are now just sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ffe485eec858544059ccb24427ac6a2
https://doi.org/10.1016/b978-0-12-820682-9.00001-3

Systematic underestimation of the epigenetic clock and age acceleration in older subjects

Autor: T.J. Gorrie-Stone, Meena Kumari, Eilis Hannon, Joe Burrage, Jonathan Mill, Amanda Hughes, Leonard C. Schalkwyk, Alexandria Andrayas, Yanchun Bao, Louis El Khoury, Melissa C. Smart

Publikováno v: El Khoury, L Y, Gorrie-Stone, T, Smart, M, Hughes, A, Bao, Y, Andrayas, A, Burrage, J, Hannon, E, Kumari, M, Mill, J & Schalkwyk, L C 2019, ' Systematic underestimation of the epigenetic clock and age acceleration in older subjects ', Genome Biology, vol. 20, no. 1, 283 . https://doi.org/10.1186/s13059-019-1810-4
Genome Biology, Vol 20, Iss 1, Pp 1-10 (2019)
Genome Biology

Background The Horvath epigenetic clock is widely used. It predicts age quite well from 353 CpG sites in the DNA methylation profile in unknown samples and has been used to calculate “age acceleration” in various tissues and environments. Results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f045b3c78ce9f4893355db692afda71a
https://research-information.bris.ac.uk/en/publications/dd2910d1-0b0b-4c31-ae81-081a5d898ba5

The endocannabinoid gene faah2a modulates stress-associated behavior in zebrafish

Autor: Louis El Khoury, Karl J. Clark, Randall G. Krug, Morgan O. Petersen, Ashley N. Sigafoos, Han B. Lee

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0190897 (2018)

The ability to orchestrate appropriate physiological and behavioral responses to stress is important for survival, and is often dysfunctional in neuropsychiatric disorders that account for leading causes of global disability burden. Numerous studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba4561ea6c7b060334588c910932fea
http://europepmc.org/articles/PMC5756047

Human Genetic Variation, Sport and Exercise Medicine, and Achilles Tendinopathy: Role for Angiogenesis-Associated Genes

Autor: Masouda Rahim, Alison V. September, Malcolm Collins, Louis El Khoury, Michael Posthumus, Stuart M Raleigh, William J Ribbans

Publikováno v: Omics : a journal of integrative biology. 20(9)

Sport and Exercise Medicine is one of the important subspecialties of 21st century healthcare contributing to improving the physical function, health, and vitality of populations while reducing the prevalence of lifestyle-related diseases. Moreover,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45138cc2837a1c0a758619df5eb05a2
https://pubmed.ncbi.nlm.nih.gov/27631191