Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Louis E. DeFrate"'
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 5, Iss 3, Pp 100378- (2023)
Objective: The measurement of in vivo intervertebral disc (IVD) mechanics may be used to understand the etiology of IVD degeneration and low back pain (LBP). To this end, our lab has developed methods to measure IVD morphology and uniaxial compressiv
Externí odkaz:
https://doaj.org/article/ae93c680c7d444c0801e6e4337e0f59f
Autor:
James A. Coppock, Amy L. McNulty, Kathryn N. Porter Starr, Abigail G. Holt, Michael S. Borack, Andrzej S. Kosinski, Amber T. Collins, Connie W. Bales, Louis E. DeFrate
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 5, Iss 3, Pp 100376- (2023)
Objective: To examine the effects of a 6-month weight loss intervention on physical function, inflammatory biomarkers, and metabolic biomarkers in both those with and without osteoarthritis (OA). Design: 59 individuals ≥60 years old with obesity an
Externí odkaz:
https://doaj.org/article/a514605e78d84ac5a1e28dbec7753169
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Segmentation of medical images into different tissue types is essential for many advancements in orthopaedic research; however, manual segmentation techniques can be time- and cost-prohibitive. The purpose of this work was to develop a semi-
Externí odkaz:
https://doaj.org/article/fa3d4cba89e54fce99383b58d6cf710d
Autor:
Sophia Y. Kim-Wang, Abigail G. Holt, Alyssa M. McGowan, Stephanie T. Danyluk, Adam P. Goode, Brian C. Lau, Alison P. Toth, Jocelyn R. Wittstein, Louis E. DeFrate, John S. Yi, Amy L. McNulty
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Anterior cruciate ligament (ACL) and meniscus tears are common knee injuries. Despite the high rate of post-traumatic osteoarthritis (PTOA) following these injuries, the contributing factors remain unclear. In this study, we chara
Externí odkaz:
https://doaj.org/article/21008987610b4cc49e08ac1a956fd7f9
Autor:
John T. Martin, Benjamin Wesorick, Alexander B. Oldweiler, Andrzej S. Kosinski, Adam P. Goode, Louis E. DeFrate
Publikováno v:
JOR Spine, Vol 5, Iss 2, Pp n/a-n/a (2022)
Abstract Background The lumbar discs are large, dense tissues that are primarily avascular, and cells residing in the central region of the disc are up to 6–8 mm from the nearest blood vessel in adults. To maintain homeostasis, disc cells rely on n
Externí odkaz:
https://doaj.org/article/59665d9151e8437b968b558fbec35796
Autor:
Amber T. Collins, Guoli Hu, Hunter Newman, Michael H. Reinsvold, Monique R. Goldsmith, John N. Twomey-Kozak, Holly A. Leddy, Deepika Sharma, Leyao Shen, Louis E. DeFrate, Courtney M. Karner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Osteoarthritis is a debilitating disease characterized by cartilage degradation and altered cartilage mechanical properties. Furthermore, it is well established that obesity is a primary risk factor for osteoarthritis. The purpose of this st
Externí odkaz:
https://doaj.org/article/3a6956c4a3614608acf2c34be56a4605
Autor:
Jacqueline N. Foody, Patrick X. Bradley, Charles E. Spritzer, Jocelyn R. Wittstein, Louis E. DeFrate, Zoë A. Englander
Publikováno v:
The American Journal of Sports Medicine. 51:422-428
Background: Noncontact anterior cruciate ligament (ACL) injuries typically occur during deceleration movements such as landing or cutting. However, conflicting data have left the kinematic mechanisms leading to these injuries unclear. Quantifying the
Autor:
Patrick X. Bradley, Karl N. Thomas, Avery L. Kratzer, Allison C. Robinson, Jocelyn R. Wittstein, Louis E. DeFrate, Amy L. McNulty
Publikováno v:
Current Rheumatology Reports. 25:35-46
Autor:
Adam P. Goode, Todd A. Schwartz, Yvonne M. Golightly, Rebecca J. Cleveland, Richard H. Gracely, Jordan B. Renner, Steven Z. George, Louis E. DeFrate, David G Hu, Virginia B. Kraus, Joanne M. Jordan
Publikováno v:
Arthritis Care & Research. 74:1659-1666
To determine the incidence and worsening of lumbar spine structure and low back pain (LBP) and whether they are predicted by demographic characteristics or clinical characteristics or appendicular joint osteoarthritis (OA).Paired baseline (2003-2004)
Autor:
John T. Martin, Alexander B. Oldweiler, Andrzej S. Kosinski, Charles E. Spritzer, Brian J. Soher, Melissa M. Erickson, Adam P. Goode, Louis E. DeFrate
Publikováno v:
European Spine Journal. 31:746-754