Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Louis D. Falo, Jr."'
Autor:
Stephen C. Balmert, Zohreh Gholizadeh Ghozloujeh, Cara Donahue Carey, Li’an H. Williams, Jiying Zhang, Preeti Shahi, Maher Amer, Tina L. Sumpter, Geza Erdos, Emrullah Korkmaz, Louis D. Falo, Jr.
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105045- (2022)
Summary: Sustainable global immunization campaigns against COVID-19 and other emerging infectious diseases require effective, broadly deployable vaccines. Here, we report a dissolvable microarray patch (MAP) SARS-CoV-2 vaccine that targets the immuno
Externí odkaz:
https://doaj.org/article/ecf940f82be949dab711a9d7dd51cc64
Autor:
Peng Wang, Meaghan E. Killeen, Tina L. Sumpter, Laura K. Ferris, Louis D. Falo, Jr., Bruce A. Freeman, Francisco J. Schopfer, Alicia R. Mathers
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101987- (2021)
Psoriasis is a chronic inflammatory skin disease with no cure. Although the origin of psoriasis and its underlying pathophysiology remain incompletely understood, inflammation is a central mediator of disease progression. In this regard, electrophili
Externí odkaz:
https://doaj.org/article/4b0d7cf207144e3e87124caa4fa7109b
Autor:
Eun Kim, Geza Erdos, Shaohua Huang, Thomas W. Kenniston, Stephen C. Balmert, Cara Donahue Carey, V. Stalin Raj, Michael W. Epperly, William B. Klimstra, Bart L. Haagmans, Emrullah Korkmaz, Louis D. Falo, Jr., Andrea Gambotto
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Background: Coronaviruses pose a serious threat to global health as evidenced by Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and COVID-19. SARS Coronavirus (SARS-CoV), MERS Coronavirus (MERS-CoV), and the novel
Externí odkaz:
https://doaj.org/article/c18eb079b315427695bd9e3c957d5fc7
Autor:
Adrian E. Morelli, Tina L. Sumpter, Darling M. Rojas-Canales, Mohna Bandyopadhyay, Zhizhao Chen, Olga Tkacheva, William J. Shufesky, Callen T. Wallace, Simon C. Watkins, Alexandra Berger, Christopher J. Paige, Louis D. Falo, Jr., Adriana T. Larregina
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3448-3465.e8 (2020)
Summary: Efficient Ca2+ flux induced during cognate T cell activation requires signaling the T cell receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs). T cells express the neurokinin-1 receptor (NK1R), a GPCR that mediates Ca2+ flux
Externí odkaz:
https://doaj.org/article/8754f15be35f40a1af5f7a3af7cdad07
Autor:
Xingxing Hao, Louis D Falo III, Guo Chen, Jiying Zhang, Cara D Carey, Walter J Storkus, Louis D Falo Jr, Zhaoyang You
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
BackgroundDespite the remarkable benefits associated with the interventional treatment of melanomas (and other solid cancers) with immune checkpoint and Braf inhibitors (Brafi), most patients ultimately progress on therapy. The presence of multifocal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717fb02489225072ea8a033cd699c81f
http://europepmc.org/articles/PMC7789470
http://europepmc.org/articles/PMC7789470
Autor:
Rebecca G Pomerantz, Timothy J Patton, Jr, Albert D Donnenberg, Ezra D Mirvish, Louis D Falo, Jr, Larisa J Geskin
Publikováno v:
The Journal of Immunology. 182:88.10-88.10
The objective of this study was to evaluate the T cell receptor-Vβ (TCR-Vβ; Vβ) repertoire in patients with Mycosis Fungoides (MF) and Sezary Syndrome (SS) variants of cutaneous T cell lymphoma (CTCL) across all stages, in order to identify relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3cc6c847746428cbac347c38e813789
https://doi.org/10.4049/jimmunol.182.supp.88.10
https://doi.org/10.4049/jimmunol.182.supp.88.10
Publikováno v:
The Journal of Immunology. 182:78.32-78.32
The development of strategies to efficiently and specifically deliver antigen to antigen presenting cells (APCs) in vivo is a major goal of vaccine design. Internalization of antigen by APCs is a crucial step in immune activation and the mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::740ac8453aedb1e8de4268e84bc59ef3
https://doi.org/10.4049/jimmunol.182.supp.78.32
https://doi.org/10.4049/jimmunol.182.supp.78.32
Publikováno v:
The Journal of Immunology. 182:132.19-132.19
The skin contains a high density of accessible dendritic cells making it an attractive target for vaccine delivery. However, the remarkable barrier function of the skin continues to present a formidable physical obstacle to cutaneous vaccine design.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cdca5015a098d63eaa2286db88cf8e5
https://doi.org/10.4049/jimmunol.182.supp.132.19
https://doi.org/10.4049/jimmunol.182.supp.132.19
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 315-320 (2016)
Since it emerged in Brazil in May 2015, the mosquito-borne Zika virus (ZIKV) has raised global concern due to its association with a significant rise in the number of infants born with microcephaly and neurological disorders such as Guillain-Barré s
Externí odkaz:
https://doaj.org/article/03ed0ac75028449cb600ae40b510ed1d
Autor:
Rhonda M. Brand, John Mark Stottlemyer, Rachel A. Cline, Cara Donahue, Jaideep Behari, Louis D. Falo Jr.
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 3009-3028 (2015)
Alcoholics suffer from immune dysfunction that can impede vaccine efficacy. If ethanol (EtOH)-induced immune impairment is in part a result of direct exposure of immune cells to EtOH, then reduced levels of exposure could result in less immune dysfun
Externí odkaz:
https://doaj.org/article/b98de90b7b324e38b88f2b54473e6903