Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Louis Charles Fortier"'
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
With the antibiotic crisis and the rise in antimicrobial resistance worldwide, new therapeutic alternatives are urgently needed. Phage therapy represents one of the most promising alternatives but for some pathogens, such as Clostridioides difficile,
Externí odkaz:
https://doaj.org/article/0da3cf3a7f054854962ab59eeaee18bc
Autor:
Julian R. Garneau, Véronique Legrand, Martial Marbouty, Maximilian O. Press, Dean R. Vik, Louis-Charles Fortier, Matthew B. Sullivan, David Bikard, Marc Monot
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Viruses that infect bacteria (phages) are increasingly recognized for their importance in diverse ecosystems but identifying and annotating them in large-scale sequence datasets is still challenging. Although efficient scalable virus identif
Externí odkaz:
https://doaj.org/article/7415601f7f3444748212a6542a24a5c2
Autor:
Julian R. Garneau, Véronique Legrand, Martial Marbouty, Maximilian O. Press, Dean R. Vik, Louis-Charles Fortier, Matthew B. Sullivan, David Bikard, Marc Monot
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/fd4d08e54b164a089c0fcccd65204aef
Autor:
Kurt Selle, Joshua R. Fletcher, Hannah Tuson, Daniel S. Schmitt, Lana McMillan, Gowrinarayani S. Vridhambal, Alissa J. Rivera, Stephanie A. Montgomery, Louis-Charles Fortier, Rodolphe Barrangou, Casey M. Theriot, David G. Ousterout
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Clostridioides difficile is an important nosocomial pathogen that causes approximately 500,000 cases of C. difficile infection (CDI) and 29,000 deaths annually in the United States. Antibiotic use is a major risk factor for CDI because broad
Externí odkaz:
https://doaj.org/article/05d3dd5ddad5489e8af88e62d8ba3612
Autor:
Jennifer Valdes, Jessica Gagné‐Sansfaçon, Vilcy Reyes, Anny Armas, Gisela Marrero, Mitterrand Moyo‐Muamba, Sheela Ramanathan, Nathalie Perreault, Subburaj Ilangumaran, Nathalie Rivard, Louis‐Charles Fortier, Alfredo Menendez
Publikováno v:
The Anatomical Record. 306:1165-1183
The effect of Western diets in the gastrointestinal system is largely mediated by their ability to promote alterations in the immunity and physiology of the intestinal epithelium, and to affect the composition of the commensal microbiota. To investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9cee129c28728c7c661e796df4fa54
https://doi.org/10.1002/ar.25083
https://doi.org/10.1002/ar.25083
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The worrying rise of antibiotic resistance in pathogenic bacteria is leading to a renewed interest in bacteriophages as a treatment option. Novel sequencing technologies enable description of an increasing number of phage genomes, a critical
Externí odkaz:
https://doaj.org/article/f7de9c00525a49ff9dc9d8b9e894e1b8
Autor:
Sarah Tremblay, Nathalie Marie Louise Côté, Guillaume Grenier, Gabriella Duclos-Lasnier, Louis-Charles Fortier, Subburaj Ilangumaran, Alfredo Menendez
Publikováno v:
Immunity & Ageing, Vol 14, Iss 1, Pp 1-5 (2017)
Abstract In an effort to understand the mechanisms underlying the high prevalence of gastrointestinal tract disorders in old age, we investigated the expression of intestinal antimicrobial peptides in the terminal small intestine of aged mice. Our re
Externí odkaz:
https://doaj.org/article/b1071c9bfbd64983838c5bd0d4561005
Autor:
Alicia Molina Kautzman, Jeanne Masunga Faida Mobulakani, Gisela Marrero Cofino, Akouavi Julite Irmine Quenum, Anny Armas Cayarga, Claude Asselin, Louis‐Charles Fortier, Subburaj Ilangumaran, Alfredo Menendez, Sheela Ramanathan
Publikováno v:
The Anatomical Record. 306:1111-1130
Inflammatory bowel diseases (IBDs) are characterized by abnormal, non-antigen specific chronic inflammation of unknown etiology. Genome-wide association studies show that many IBD genetic susceptibility loci map to immune function genes and compellin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c924dfb62d68f8bd78de782e969ffa
https://doi.org/10.1002/ar.25044
https://doi.org/10.1002/ar.25044
Autor:
Alexia L. M. Royer, Andrew A. Umansky, Marie-Maude Allen, Julian R. Garneau, Maicol Ospina-Bedoya, Joseph A. Kirk, Gregory Govoni, Robert P. Fagan, Olga Soutourina, Louis-Charles Fortier
Publikováno v:
Microbiology Spectrum. 11
Phage therapy represents an interesting alternative to treat Clostridioides difficile infections because, contrary to antibiotics, most phages are highly species specific, thereby sparing the beneficial gut microbes that protect from infection. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b1cc7704b20e69fae14f2e380db6da1
https://doi.org/10.1128/spectrum.03894-22
https://doi.org/10.1128/spectrum.03894-22
Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027)Clostridioides difficile
Autor:
Qiwen Dong, Huaiying Lin, Marie-Maude Allen, Julian R. Garneau, Jonathan K. Sia, Rita C. Smith, Fidel Haro, Tracy McMillen, Rosemary L. Pope, Carolyn Metcalfe, Victoria Burgo, Che Woodson, Nicholas Dylla, Claire Kohout, Anitha Sundararajan, Evan S Snitkin, Vincent B. Young, Louis-Charles Fortier, Mini Kamboj, Eric G. Pamer
Clostridioides difficile (C. difficile), a leading cause of nosocomial infection, produces toxins that damage the colonic epithelium and results in colitis that varies from mild to fulminant. Variation in disease severity is poorly understood and has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49db5b53e23e342771784139edafea31
https://doi.org/10.1101/2023.01.12.523823
https://doi.org/10.1101/2023.01.12.523823
