Výsledky vyhledávání - "Louis CARREGA"

Prognostic value of ischaemia-modified albumin in patients with non-ST-segment elevation acute coronary syndromes

Autor: Jean-Louis Bonnet, Thomas Cuisset, Christopher Mielot, Colette Monserrat, Jacques Quilici, Jean-Philippe Mouret, Roch Giorgi, Marc Lambert, Louis Carrega, Laurent Bali, Régis Guieu, Lyassine Nait-Saidi

Publikováno v: Archives of Cardiovascular Diseases. 101(10):645-651

Objectif. - L'albumine modifiee par l'ischemie (IMA) est un biomarqueur diagnostique precoce de l'ischemie myocardique. Notre etude avait pour objectif d'evaluer la valeur pronostique de l'IMA chez les patients hospitalises pour syndrome coronaire ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0143ce1d015f90e1434367a92dab0af

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Release of Markers of Myocardial Damage Evaluated in the Coronary Sinus during Cardiac Surgery

Autor: Youlet By, Régis Guieu, Frederic Collard, François Benard, Pierre-Jean Lejeune, François Kerbaul, A Saadjian, Jean-Louis Bonnet, Frauck Paganelli, Colette Monserrat, Ibrahim Zouher, Bernard Mallet, Louis Carrega, Jean Ruf

Publikováno v: Journal of Investigative Medicine. 55:195-201

Myocardial damage is a frequent complication of cardiac surgery by direct mechanical trauma during the surgical procedure and by myocardial ischemia, which occurs during the cardiopulmonary bypass (CBP). Because the concentrations of biomarkers in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ea8c3bd51bef19f3a97f410637ed86
https://doi.org/10.2310/6650.2007.06046

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Small conductance calcium-activated K+ channels, SkCa, but not voltage-gated K+ (Kv) channels, are implicated in the antinociception induced by CGS21680, a A2A adenosine receptor agonist

Autor: Nicolas Andreotti, Hervé Rochat, H. Vacher, T. Pham, N. Sauze, Imed Regaya, Marie-France Martin-Eauclaire, Christiane Devaux, Régis Guieu, Besma Jouirou, J. C. Peragut, Jean-Marc Sabatier, Louis Carrega

Publikováno v: Life Sciences. 76:367-377

It has been shown that A2A adenosine receptors are implicated in pain modulation. The precise mechanism by which activation of A2A receptors produces analgesic effects, however, remains unclear. The aim of this study was to investigate the possible i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79ead0cda6e10c974062b078df91b4c
https://doi.org/10.1016/j.lfs.2004.06.023

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Kinetic study of adenosine concentrations and the expression of adenosine deaminase in mononuclear cells during hemodialysis

Autor: Laurence Mercier, Emmanuel Fenouillet, Radj Purgus, Nicole Sauze, Régis Guieu, Ibrahim Zouher, Guy Bechis, Yvon Berland, Phillippe Brunet, Louis Carrega, Bertrand Dussol

Publikováno v: Kidney International. 66(4):1640-1646

Kinetic study of adenosine concentrations and the expression of adenosine deaminase in mononuclear cells during hemodialysis. Background We previously showed that high intralymphocytic adenosine (Ado) concentrations are found in hemodialyzed patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbce61bcb5baeecdb813ff5c51ee9a3

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Supraspinal Antinociceptive Effects of μ and δ Agonists Involve Modulation of Adenosine Uptake

Autor: Christiane Devaux, Odile Fund-Saunier, Régis Guieu, Jean-Claude Peragut, Louis Carrega, A Saadjian, Nicole Sauze, Thao Pham

Publikováno v: Anesthesiology. 98:459-464

Background The modulation of extracellular adenosine concentration by opioids provides evidence that the antinociceptive effects of these compounds involve endogenous adenosine. The aim of this study was to determine whether there is a relation betwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290f63fab3e4bbefd4ec9e4f53ff69fc
https://doi.org/10.1097/00000542-200302000-00027

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Evolution of maurotoxin conformation and blocking efficacy towards Shaker B channels during the course of folding and oxidation in vitro

Autor: Eric DI LUCCIO, Alessandra MATAVEL, Sandrine OPI, Imed REGAYA, Guillaume SANDOZ, Sarrah M'BAREK, Edmond CARLIER, Eric ESTÈVE, Louis CARREGA, Ziad FAJLOUN, Hervé ROCHAT, Erwann LORET, Michel DE WAARD, Jean-Marc SABATIER

Publikováno v: Biochemical Journal. 361:409-416

Maurotoxin (MTX) is a 34-mer scorpion toxin cross-linked by four disulphide bridges that acts on various K+ channels, including the voltage-gated Shaker B subtype. In the present study, we have investigated over 80h: (1) the time-course of folding of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e72d14ebfb2b9e5daaa63a9a68b2b6af
https://doi.org/10.1042/bj3610409

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Adenosine and Hemodialysis in Humans

Autor: Bertrand Dussol, J. L. Mege, D. Lerda, Emmanuel Fenouillet, Hervé Rochat, Christian Capo, Joana Vitte, Philippe Brunet, Guy Bechis, Jerome Sampol, Louis Carrega, Yvon Berland, Zouher Ibrahim, Régis Guieu

Publikováno v: Journal of Investigative Medicine. 49:56-67

Background Infections and hypotension are serious complications that develop during hemodialysis (HD) treatment. Adenosine (ADO), a strong hypotensive and immunosuppressive agent, may participate in these two HD complications, because high concentrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37143d8a3a4615c2816708968913ce7e
https://doi.org/10.2310/6650.2001.34091

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Expeditious synthesis and biological evaluation of new C-6 1,2,3-triazole adenosine derivatives A1 receptor antagonists or agonists

Autor: Laurent Commeiras, Smitha C. Mathew, Gaëlle Chouraqui, Marie-Alice Virolleaud, Jocelyne Condo, Jean Rodriguez, Anouk Gaudel-Siri, Youlet By, Jean Ruf, Régis Guieu, Jean-Luc Parrain, Aurélie Berthault, Mireille Attolini, Louis Carrega

Publikováno v: Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2010, 8 (17), pp.3874-81. ⟨10.1039/c0ob00017e⟩
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2010, 8, pp.3874. ⟨10.1039/c0ob00017e⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2010, 8 (17), pp.3874-81. ⟨10.1039/c0ob00017e⟩
Organic & Biomolecular Chemistry, 2010, 8, pp.3874. ⟨10.1039/c0ob00017e⟩

International audience; The synthesis of new C-6 1,2,3-triazole adenosine derivatives via microwave assisted 1,3-dipolar cycloaddition as key step is described. The binding on membranes of cells that over express A(1) adenosine receptors (A(1)AR) was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72328199fbe978ce388af8f881b6a75d
https://hal.science/hal-00682114

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Design, Synthesis and Biological evaluation of a bivalent µ opiate and adenosine A1 receptor antagonist

Autor: Louis Carrega, Jocelyne Condo, Aurélie Berthault, Laurent Commeiras, Mireille Attolini, Gaëlle Chouraqui, Jean Ruf, Régis Guieu, Youlet By, Nandita Ghosh, Jean-Luc Parrain, Jean Rodriguez, Smitha C. Mathew, Anouk Gaudel-Siri, Marie-Alice Virolleaud

Publikováno v: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2009, 19, pp.6736. ⟨10.1016/j.bmcl.2009.09.112⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19, pp.6736. ⟨10.1016/j.bmcl.2009.09.112⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19, pp.6736-6739. ⟨10.1016/j.bmcl.2009.09.112⟩
Bioorganic and Medicinal Chemistry Letters, 2009, 19, pp.6736-6739. ⟨10.1016/j.bmcl.2009.09.112⟩

The cross talk between different membrane receptors is the source of increasing research. We designed and synthesized a new hetero-bivalent ligand that has antagonist properties on both A(1) adenosine and mu opiate receptors with a K(i) of 0.8+/-0.05

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dca52f1f35f9d3891ec9961903b68b
https://hal.science/hal-01407732

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Adenosine A2A receptor hyperexpression in patients with severe SIRS after cardiopulmonary bypass

Autor: Roch Giorgi, V. Gerolami, Dorothée Blayac, Fréderic Benard, Louis Carrega, François Kerbaul, Ibrahim Zouher, Vincent Bénas, Youlet, Régis Guieu, Vlad Gariboldi, Laurence Mercier, Frederic Collart

Publikováno v: ResearcherID

Objective Adenosine (ADO) is an endogenous nucleoside, which has been involved in blood pressure failure during severe systemic inflammatory response syndrome (severe SIRS) after cardiac surgery with cardiopulmonary bypass (CPB). Adenosine acts via i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66492085b692441f3f220d834bef0b95
https://pubmed.ncbi.nlm.nih.gov/18667904

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