Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Louis C. Tan"'
Autor:
Yih Ru Wu, Louis C Tan, Xiaoli Fu, Chiung Mei Chen, Wing Lok Au, Ling Chen, Yi Chun Chen, Kumar M Prakash, Yifan Zheng, Guey-Jen Lee-Chen, Yi Zhao, Jin-Sheng Zeng, Eng King Tan, Zhong Pei
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e36123 (2012)
It has been suggested that a common LRRK2 polymorphic variant (A419V (rs34594498 C >T)) may be a risk factor among Asians (especially in Taiwan). In this study, we examined this variant in a larger and independent Taiwan cohort. We found the frequenc
Externí odkaz:
https://doaj.org/article/55aee1dd9a6d4fb48fe77f101fcf8254
Autor:
Alberto Albanese, H.A. Jinnah, Puneet Opal, Daniel Truong, Yun Cheng Wu, Werner Poewe, Francisco Cardoso, Carlo Colosimo, Christine Hui Shan Chan, K. Ray Chaudhuri, Shen-Yang Lim, Beomseok Jeon, Eng-King Tan, Louis C. Tan, Pramod Kumar Pal
Publikováno v:
Journal of the Neurological Sciences
Autor:
Ishak D. Irwan, Jianjun Liu, Kyuyoung Song, E-Shyong Tai, Ho-Sung Ryu, Myunghee Hong, Herty Liany, Jimmy Lee, Tien Yin Wong, Louis C. Tan, Tat Hung Koh, Chiea Chuen Khor, Siow Ann Chong, Sun Ju Chung, Tin Aung, Jia Nee Foo, Wing Lok Au, Kumar M. Prakash, Ching-Yu Cheng, Eranga N. Vithana, Eng-King Tan
Publikováno v:
Movement Disorders. 31:484-487
Background Genome-wide association studies have identified several loci associated with Parkinson's disease (PD). Whole-exome sequencing detects rare coding variants, but their links with PD genome-wide association study loci are unknown. Our objecti
Autor:
Bin Xiao, Yew Long Lo, Xiao Deng, Louis C. Tan, Eng-King Tan, Yu-Lin Ng, John Carson Allen, Jia Nee Foo
Publikováno v:
SSRN Electronic Journal.
Background: Data on the long-term motor outcomes of GWAS-linked Parkinson disease (PD) carriers will be useful for clinical management. Methods: Over a 9-year period, carriers of PARK16 rs11240572 variant and non-carriers were followed up and evaluat
Autor:
Wing Lok Au, Louis C. Tan, Kumar M. Prakash, Y.-Y. Ng, Jianjun Liu, H.-K. Kwok, Yi Zhao, Tatsushi Toda, Eng-King Tan, R. Pavanni, Wataru Satake, W.-T. Zhao
Publikováno v:
Neurology. 75:508-512
Objective: A genome-wide association study (GWAS) in the Japanese population identified 2 new Parkinson disease (PD) susceptibility loci on 1q32 (PARK16) (OMIM 613164) and BST1. We analyzed single nucleotide polymorphism (SNPs) located at the GWAS-li
Publikováno v:
Quality of Life Research. 19:565-569
The purpose of this study was to evaluate the responsiveness of the EQ-5D and the Parkinson’s Disease Questionnaire (PDQ-8) to deterioration in health-related quality of life (HRQoL) in patients with Parkinson’s disease (PD). HRQoL and clinical d
Publikováno v:
Neurology. 71:1727-1732
Objectives: To assess the association of ATP13A2 gene mutation among patients with early onset Parkinson disease (EOPD, onset Methods: Among 771 subjects, we studied 182 patients with EOPD and familial PD and 589 matched controls from two cohorts of
The LRRK2 Gly2385Arg variant is associated with Parkinson's disease: genetic and functional evidence
Autor:
L. Sun, R. Pavanni, Eng-King Tan, Chin Song Lu, Jianjun Liu, Prasanna R. Kolatkar, Lisa Skipper, Yih Yuen, E. Chua, Vincenzo Bonifati, Yi Zhao, Meng-Cheong Wong, M. G. Tan, S. Tang, Louis C. Tan, Stephanie Fook-Chong, A. Di Fonzo
Publikováno v:
Human Genetics, 120(6), 857-863. Springer-Verlag
Evidence of LRRK2 haplotypes associated with Parkinson's disease (PD) risk was recently found in the Chinese population from Singapore, and a common LRRK2 missense variant, Gly2385Arg, was independently detected as a putative risk factor for PD in th
Autor:
Jia Nee, Foo, Sun Ju, Chung, Louis C, Tan, Herty, Liany, Ho-Sung, Ryu, Myunghee, Hong, Tat Hung, Koh, Ishak D, Irwan, Wing-Lok, Au, Kumar-M, Prakash, Tin, Aung, Ching-Yu, Cheng, Siow-Ann, Chong, Chiea Chuen, Khor, Jimmy, Lee, E-Shyong, Tai, Eranga N, Vithana, Tien-Yin, Wong, Kyuyoung, Song, Jianjun, Liu, Eng-King, Tan
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 31(4)
Genome-wide association studies have identified several loci associated with Parkinson's disease (PD). Whole-exome sequencing detects rare coding variants, but their links with PD genome-wide association study loci are unknown. Our objective was to i
Autor:
Louis C. Tan, S. Y. Lum, A. Tan, Y. Yih, Meng-Cheong Wong, M.L. Teoh, Stephanie Fook-Chong, Eng-King Tan
Publikováno v:
Neurology. 58:465-468
The authors found a significantly higher prevalence of daytime somnolence in 201 patients with PD compared with 214 age- and sex-matched healthy control subjects (Epworth Sleepiness Scale score 5.6 vs 4.6). The prevalence of “sleep attacks” (SA)