Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Louis Bourgeois, A."'
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1087 (2024)
Enterotoxigenic Escherichia coli (ETEC) is the most prevalent bacterial pathogen causing young children to suffer acute watery diarrhea in Low- and Middle-Income Countries (LMICs) [...]
Externí odkaz:
https://doaj.org/article/d68126317f8441d098d498e05e5bfb4e
Autor:
Kawsar R. Talaat, Chad K. Porter, Subhra Chakraborty, Brittany L. Feijoo, Jessica Brubaker, Brittany M. Adjoodani, Barbara DeNearing, Michael G. Prouty, Steven T. Poole, A. Louis Bourgeois, Madison Billingsley, David A. Sack, Susanne Eder-Lingelbach, Christian Taucher
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 727 (2024)
Controlled human infection models are important tools for the evaluation of vaccines against diseases where an appropriate correlate of protection has not been identified. Enterotoxigenic Escherichia coli (ETEC) strain LSN03-016011/A (LSN03) is an LT
Externí odkaz:
https://doaj.org/article/5f3a34f3ebdc48288a3296a738ed5782
Autor:
Richard I. Walker, A. Louis Bourgeois
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Oral immunization is an effective strategy for inducing protective immunity against mucosal enteric pathogens. Although live-attenuated as well as subunit approaches have been explored for vaccination against enteric pathogens, inactivated whole bact
Externí odkaz:
https://doaj.org/article/32f042d853254b87965c8029738a5c7b
Autor:
Nicole Maier, Shannon L. Grahek, Jane Halpern, Suzanne Restrepo, Felipe Troncoso, Janet Shimko, Olga Torres, Jaime Belkind-Gerson, David A. Sack, Ann-Mari Svennerholm, Björn Gustafsson, Björn Sjöstrand, Nils Carlin, A. Louis Bourgeois, Chad K. Porter
Publikováno v:
Microorganisms, Vol 11, Iss 10, p 2414 (2023)
The efficacy of an Oral Whole Cell ETEC Vaccine (OEV) against Travelers’ Diarrhea (TD) was reexamined using novel outcome and immunologic measures. More specifically, a recently developed disease severity score and alternative clinical endpoints we
Externí odkaz:
https://doaj.org/article/369c3920388d46768fce8147e5741cf4
Autor:
Hyesuk Seo, Ti Lu, Sachin Mani, A. Louis Bourgeois, Richard Walker, David A. Sack, Weiping Zhang
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 2, Pp 419-425 (2020)
Double-mutant heat-labile toxin (dmLT, LTR192G/L211A) of enterotoxigenic Escherichia coli (ETEC) is an effective mucosal adjuvant. Recent studies have shown that dmLT also exhibits adjuvanticity for antigens administered parenterally. In this study,
Externí odkaz:
https://doaj.org/article/ddf7d0243b6745b9837a1dd79228b52e
Autor:
Mette Thorsing, Thøger Jensen Krogh, Lars Vitved, Arkadiusz Nawrocki, Rikke Jakobsen, Martin R. Larsen, Subhra Chakraborty, A. Louis Bourgeois, Ann Zahle Andersen, Anders Boysen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Enterotoxigenic Escherichia coli (ETEC) is a WHO priority pathogen and vaccine target which causes infections in low-income and middle-income countries, travelers visiting endemic regions. The global urgent demand for an effective preventive interven
Externí odkaz:
https://doaj.org/article/2b2c220e839344f1ab6811b399163511
Autor:
Kristen A. Clarkson, Chad K. Porter, Kawsar R. Talaat, Robert W. Frenck, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Robert W. Kaminski
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
Although immune correlates of protection have yet to be defined for shigellosis, prior studies have demonstrated that Shigella
Externí odkaz:
https://doaj.org/article/00faf9dd413e4683a25862248fbc8e09
Autor:
Mark S. Riddle, A. Louis Bourgeois, Allison Clifford, Suhi Jeon, Birgitte K. Giersing, Mark Jit, Marta Tufet Bayona, Jared Ovitt, William P. Hausdorff
Publikováno v:
Vaccine. 41:2634-2644
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5f67adb2c4efd514d18d11e932a2dc
https://doi.org/10.1016/j.vaccine.2023.03.003
https://doi.org/10.1016/j.vaccine.2023.03.003
Autor:
Kawsar R. Talaat, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Anita M. Dreyer, Robert W. Kaminski, Chad K. Porter, Subhra Chakraborty, Kristen A. Clarkson, Jessica Brubaker, Daniel Elwood, Rahel Frölich, Barbara DeNearing, Hailey Weerts, Brittany L. Feijoo, Jane Halpern, David Sack, Mark S. Riddle, Veronica Gambillara Fonck
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103310- (2021)
Background: Shigellosis is a major cause of moderate to severe diarrhoea and dysentery in children under 5 years of age in low and middle-income countries. The Flexyn2a vaccine conjugates the O-polysaccharide of Shigella flexneri 2a to Pseudomonas ae
Externí odkaz:
https://doaj.org/article/1410f37230014cc3bbc215ab53fb2558
Autor:
Kristen A. Clarkson, Kawsar R. Talaat, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Anita Dreyer, Chad K. Porter, Subhra Chakraborty, Jessica Brubaker, Daniel Elwood, Rahel Frölich, Barbara DeNearing, Hailey P. Weerts, Brittany Feijoo, Jane Halpern, David Sack, Mark S. Riddle, Veronica Gambillara Fonck, Robert W. Kaminski
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103308- (2021)
Background: Diarrheal diseases are a leading cause of global morbidity and mortality affecting all ages, but especially children under the age of five in resource-limited settings. Shigella is a leading contributor to diarrheal diseases caused by bac
Externí odkaz:
https://doaj.org/article/cce33f902cd64e25ad5106ca4d7aa302