Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Louis B. Flexner"'
Publikováno v:
International Journal of Peptide and Protein Research. 16:482-486
[Ile3, Arg8]. vasopressin (arginine-vasotocin), as well as the C-terminal tripeptides of the neurohypophyseal hormones arginine and lysine vasopressin, Pro-Arg-Gly-NH2 and Pro-Lys-Gly-NH2, were protective against puromycin-induced amnesia in mice whe
Publikováno v:
Pharmacology Biochemistry and Behavior. 52:237-240
Bitemporal injections of puromycin consistently induce amnesia of aversive maze learning in mice when administered within 3 days of training. These bitemporal puromycin injections lose their amnestic effectiveness if the latency between training and
Autor:
Louis B. Flexner, G.J. Vosburgh, Louis M. Hellman, Dean B. Cowie, Walter S. Wilde, N. K. Proctor
Publikováno v:
The Journal of pediatrics. 30(4)
Summary On the basis of dilution of a known quantity of intravenously injected sodium chloride tagged with a radioactive isotope of sodium, the extracellular fluid volume in three newborn human infants has been found to average 43.5 per cent of the b
Publikováno v:
Pharmacology, biochemistry, and behavior. 43(2)
Bitemporal injections of puromycin consistently induce amnesia of aversive maze learning in mice when given within 3 days after training. These injections consistently fail to induce amnesia when given 6 or more days after training. Consistent with t
Publikováno v:
Pharmacology, biochemistry, and behavior. 39(3)
Bitemporal injections of puromycin consistently induce amnesia of aversive maze-learning in mice when administered within 3 days of training. These bitemporal puromycin injections lose their amnestic effectiveness, if the latency between training and
Autor:
Louis B. Flexner, Josefa B. Flexner
Publikováno v:
Pharmacology Biochemistry and Behavior. 5:117-121
Bitemporal injections of puromycin that primarily affect the hippocampal-enthorhinal cortical areas suppress memory of maze-learning in mice for 3 days after training but are ineffective 6 or more days after training. At these later times, injections
Dose-response relationships in attenuation of puromycin-induced amnesia by neurohypophyseal peptides
Publikováno v:
Brain Research. 134:139-144
Summary Intracerebral injections of puromycin one day after training of mice in a Y-maze cause amnesia when the animals are tested 7 days later. This amnesia was shown to be attenuated by various neurohypophyseal hormones, analogs and fragments, admi
Autor:
Louis B. Flexner, Richard H. Goodman
Publikováno v:
Proceedings of the National Academy of Sciences. 72:4660-4663
The rates of accumulation of newly synthesized catecholamines and endogenous catecholamine levels in mice were determined after treatment with cycloheximide, acetoxycycloheximde, puromycin, and anisomycin. The rates of accumulation were found to be d
Inhibition by Z-Pro-D-Leu of development of tolerance to and physical dependence on morphine in mice
Autor:
Louis B. Flexner, William A. Krivoy, Roderich Walter, Ronald F. Ritzmann, Thomas C. Rainbow, Hemendra N. Bhargava
Publikováno v:
Proceedings of the National Academy of Sciences. 75:4573-4576
The peptide-Z-Pro-D-Leu, injected daily in mice receiving morphine chronically, was found to prevent development of physical dependence as measured by changes in body temperature and body weight due either to abrupt or to naloxone-induced withdrawal.
Publikováno v:
Pharmacology Biochemistry and Behavior. 10:787-793
Cyclo(Leu-Gly), the enzymatically resistant diketopiperazine formally derived from the C-terminal dipeptide sequence of oxytocin, exhibits activity in several behavioral systems. The distribution of cyclo(Leu-14C(U)Gly) in brain, and the time course