Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Louis A. Searcy"'
Autor:
Tamim Kawakibi, Niharika Bala, Lauren P. Liu, Louis A. Searcy, Nancy D. Denslow, Abdel A. Alli
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1489 (2023)
Cathpesin B is a multi-functional protease that plays numerous roles in physiology and pathophysiology. We hypothesized that actin cytoskeleton proteins that are substrates of cathepsin B, various lipids, and kinases that are regulated by lipids woul
Externí odkaz:
https://doaj.org/article/dbd96dc1e0234321a07b9a0d67f7c580
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 3, Pp 275-290 (2020)
Diets high in calories can be used to model metabolic diseases, including obesity and its associated comorbidities, in animals. Drosophila melanogaster fed high-sugar diets (HSDs) exhibit complications of human obesity including hyperglycemia, hyperl
Externí odkaz:
https://doaj.org/article/1caa21af52fe42738ba5bcf83ad29800
Autor:
Carlos I. Lugo, Lauren P. Liu, Niharika Bala, Angelica G. Morales, Mohammed F. Gholam, Julia C. Abchee, Nasseem Elmoujahid, Ahmed Samir Elshikha, Rigena Avdiaj, Louis A. Searcy, Nancy D. Denslow, Sihong Song, Abdel A. Alli
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 66 (2022)
Hypertension may develop before or after the onset of diabetes and it is known to increase the risk of developing diabetic nephropathy. Alpha-1 antitrypsin (AAT) is a multi-functional protein with beneficial effects in various diseases but its role i
Externí odkaz:
https://doaj.org/article/e33cb0622d164d038d065d98b67dae99
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1408
In addition to inhibiting renal glucose reabsorption and allowing for glucose excretion, the sodium/glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin may be efficacious in treating various comorbidities associated with type 2 diabetes mellitus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b36c21642a7f25d4059b0f14520b81
Publikováno v:
J Lipid Res
Diets high in calories can be used to model metabolic diseases, including obesity and its associated comorbidities, in animals. Drosophila melanogaster fed high-sugar diets (HSDs) exhibit complications of human obesity including hyperglycemia, hyperl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8896087dc83ebab3488d5ba8673ad9a1
https://pubmed.ncbi.nlm.nih.gov/31900315
https://pubmed.ncbi.nlm.nih.gov/31900315
Publikováno v:
Circulation Research. 121
Obesity is associated with cardiovascular disease in humans and a number of model organisms, including the fruit fly Drosophila melanogaster . We use a fly model of high-sugar-diet-induced metabolic disease that includes hyperglycemia, insulin resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d674a97c21a8adcfe85d4f7ff3cf6570
https://doi.org/10.1161/res.121.suppl_1.282
https://doi.org/10.1161/res.121.suppl_1.282