Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Louis A, Gatto"'
Autor:
Kishore R. Alugupalli, Sudeep Kothari, Matthew P. Cravens, Justin A. Walker, Darren T. Dougharty, Gregory S. Dickinson, Louis A. Gatto, Andreas J. Bäumler, Tamding Wangdi, Darla R. Miller, Fernando Pardo-Manuel de Villena, Linda D. Siracusa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred stra
Externí odkaz:
https://doaj.org/article/fb21c12f4f6245b4aadc14104da79dc1
Autor:
Gary Nieman, Michaela Kollisch-Singule, Harry Ramcharran, Joshua Satalin, Sarah Blair, Louis A. Gatto, Penny Andrews, Auyon Ghosh, David W. Kaczka, Donald Gaver, Jason Bates, Nader M. Habashi
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract A hallmark of ARDS is progressive shrinking of the ‘baby lung,’ now referred to as the ventilator-induced lung injury (VILI) ‘vortex.’ Reducing the risk of the VILI vortex is the goal of current ventilation strategies; unfortunately,
Externí odkaz:
https://doaj.org/article/cb0702575d9047808865109ce2f2e938
Autor:
Michaela Kollisch-Singule, Harry Ramcharran, Joshua Satalin, Sarah Blair, Louis A. Gatto, Penny L. Andrews, Nader M. Habashi, Gary F. Nieman, Adel Bougatef
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Pediatric acute respiratory distress syndrome (PARDS) remains a significant cause of morbidity and mortality, with mortality rates as high as 50% in children with severe PARDS. Despite this, pediatric lung injury and mechanical ventilation has been p
Externí odkaz:
https://doaj.org/article/de1ff3997f614239a2587ec4420c11b2
Autor:
Gary F. Nieman, Louis A. Gatto, Penny Andrews, Joshua Satalin, Luigi Camporota, Benjamin Daxon, Sarah J. Blair, Hassan Al-khalisy, Maria Madden, Michaela Kollisch-Singule, Hani Aiash, Nader M. Habashi
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Mortality in acute respiratory distress syndrome (ARDS) remains unacceptably high at approximately 39%. One of the only treatments is supportive: mechanical ventilation. However, improperly set mechanical ventilation can further increase the
Externí odkaz:
https://doaj.org/article/2169deb74dbc47f38e6f975b7a6235ac
Autor:
Melissa Mahajan, David DiStefano, Joshua Satalin, Penny Andrews, Hassan al-Khalisy, Sarah Baker, Louis A. Gatto, Gary F. Nieman, Nader M. Habashi
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in intensive care units. Distal airway mucus clearance has been shown to reduce VAP incidence. Studies suggest that mucus clearance is enhanced when the
Externí odkaz:
https://doaj.org/article/1410fde39cae4860a609b9d02e18d3c5
Autor:
Harry Ramcharran, Jason H. T. Bates, Joshua Satalin, Sarah Blair, Penny L. Andrews, Donald P. Gaver, Louis A. Gatto, Guirong Wang, Auyon J. Ghosh, Benjamin Robedee, James Vossler, Nader M. Habashi, Nirav Daphtary, Michaela Kollisch-Singule, Gary F. Nieman
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(5)
Ventilator-induced lung injury (VILI) is a significant risk for patients with acute respiratory distress syndrome (ARDS). Management of the patient with ARDS is currently dominated by the use of low tidal volume mechanical ventilation, the presumptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05348faf8cd5f172930d16585e937824
https://pubmed.ncbi.nlm.nih.gov/36135956
https://pubmed.ncbi.nlm.nih.gov/36135956
Autor:
Gary F. Nieman, Hassan Al-Khalisy, Michaela Kollisch-Singule, Joshua Satalin, Sarah Blair, Girish Trikha, Penny Andrews, Maria Madden, Louis A. Gatto, Nader M. Habashi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Acute respiratory distress syndrome (ARDS) causes a heterogeneous lung injury and remains a serious medical problem, with one of the only treatments being supportive care in the form of mechanical ventilation. It is very difficult, however, to mechan
Externí odkaz:
https://doaj.org/article/2190eec4521641e8b61753fdcaadb2d1
Autor:
Michaela Kollisch-Singule, Joshua Satalin, Sarah J. Blair, Penny L. Andrews, Louis A. Gatto, Gary F. Nieman, Nader M. Habashi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Morbidity and mortality associated with lung injury remains disappointingly unchanged over the last two decades, in part due to the current reliance on lung macro-parameters set on the ventilator instead of considering the micro-environment and the r
Externí odkaz:
https://doaj.org/article/016d733f3d4040bd90c918d61b718395
Autor:
Gary F. Nieman, Penny Andrews, Joshua Satalin, Kailyn Wilcox, Michaela Kollisch-Singule, Maria Madden, Hani Aiash, Sarah J. Blair, Louis A. Gatto, Nader M. Habashi
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-11 (2018)
Abstract The pathophysiology of acute respiratory distress syndrome (ARDS) results in heterogeneous lung collapse, edema-flooded airways and unstable alveoli. These pathologic alterations in alveolar mechanics (i.e. dynamic change in alveolar size an
Externí odkaz:
https://doaj.org/article/75038bc5c19b4f42b6b822186efd2f1e
Autor:
Sumeet V. Jain, Michaela Kollisch-Singule, Joshua Satalin, Quinn Searles, Luke Dombert, Osama Abdel-Razek, Natesh Yepuri, Antony Leonard, Angelika Gruessner, Penny Andrews, Fabeha Fazal, Qinghe Meng, Guirong Wang, Louis A. Gatto, Nader M. Habashi, Gary F. Nieman
Publikováno v:
Intensive Care Medicine Experimental, Vol 5, Iss 1, Pp 1-18 (2017)
Abstract Background Acute respiratory distress syndrome causes a heterogeneous lung injury with normal and acutely injured lung tissue in the same lung. Improperly adjusted mechanical ventilation can exacerbate ARDS causing a secondary ventilator-ind
Externí odkaz:
https://doaj.org/article/4c47d7e6c18140fa80153cb84c48400e