Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Louis Grenier"'
Autor:
Capelli, Roberta
Dans son article, Roberta Capelli analyse la nature et la fonction des éléments médiévaux les plus importants dans la production lyrique de Paul-Louis Grenier : le goût pour le fabuleux, le choix d’un décor familier, qui correspond aux lieux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::336bf9e51b9e42c7edf4ce35f613240e
Autor:
de Lasteyrie, Ch.
Publikováno v:
Bibliothèque de l’École des chartes, 1909 Jan 01. 70, 112-113.
Externí odkaz:
https://www.jstor.org/stable/42970992
Akademický článek
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Autor:
Frégeau, Mireille
Publikováno v:
Semaine; 10/27/2017, Vol. 13 Issue 38, p34-36, 3p, 5 Color Photographs
Th.--Méd.--Paris, 1840.
Voyez tome 7, page, N ° 383. Paris, 1840.
Voyez tome 7, page, N ° 383. Paris, 1840.
Externí odkaz:
http://catalogue.bnf.fr/ark:/12148/cb36887814t
Autor:
Christian M. Martin, Jennifer Proctor, Patrick O'Hearn, Janid A. Ali, Andre Lescarbeau, Jennifer Hoyt, Jonathan P. DiNitto, Ann M. Rowley, Thomas T. Tibbitts, Catherine A. Evans, Martin R. Tremblay, Tao Liu, Vito J. Palombella, John Soglia, Johan A. Pradeilles, Somarajan J. Nair, Melissa Pink, David G. Winkler, Stanley Goldstein, Quentin Glenadel, Erin L. O’Hearn, Culver Cheung, Erin Brophy, Alfredo C. Castro, Louis Grenier
Publikováno v:
ACS Medicinal Chemistry Letters. 7:862-867
Optimization of isoquinolinone PI3K inhibitors led to the discovery of a potent inhibitor of PI3K-γ (26 or IPI-549) with >100-fold selectivity over other lipid and protein kinases. IPI-549 demonstrates favorable pharmacokinetic properties and robust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f2e63c8dbb32a50d02e0a4d22c2564
https://doi.org/10.1021/acsmedchemlett.6b00238
https://doi.org/10.1021/acsmedchemlett.6b00238
Autor:
Michael Foley, Andre Lescarbeau, Martin R. Tremblay, Lombardy Richard John, Grogan Michael John, Andrew B. Hague, Kristopher M. Depew, Jimin Xiong, Joseph Helble, Priscilla L. White, Julian Adams, Brian C. Austad, Caroline D. Lory, Somarajan J. Nair, Stéphane Peluso, Lin-Chen Yu, Alfredo C. Castro, André B. Charette, Benjamin S. Lane, Jeanne Shaffer, Louis Grenier, James R. Porter, Matthew Campbell, Koney Nii O, Mark L. Behnke
Publikováno v:
Organic Process Research & Development. 20:786-798
The formation of the d-homocyclopamine ring system in IPI-926 is the key step in its semisynthesis and proceeds via a chemoselective cyclopropanation followed by a stereoselective acid-catalyzed carbocation rearrangement. In order to perform large-sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a9debb0b604cbda59d104def86c7642
https://doi.org/10.1021/acs.oprd.6b00048
https://doi.org/10.1021/acs.oprd.6b00048
Autor:
Martin Trudeau, Louis Grenier, Kristopher M. Depew, Daniel G. Genov, Alexandre Côté, Brian C. Austad, Lin-Chen Yu, Andre Lescarbeau, Theodore A. Martinot, Priscilla L. White, Joseph Helble, Somarajan J. Nair
Publikováno v:
Organic Process Research & Development. 19:1693-1702
A design of experiments (DoE) approach was taken to optimize purity and reaction yield of the final debenzylation and hydrochloride salt formation of IPI-926. The study involved a careful dissection of the different process steps to enable an indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303b6bb1bcb0f53d2408fcb4957573f0
https://doi.org/10.1021/acs.oprd.5b00214
https://doi.org/10.1021/acs.oprd.5b00214
Autor:
John Lee, Roger H. Pak, Louis Grenier, Vince Ammoscato, Michael Curtis, Kaiming Li, John Henderson, Matthew Campbell, Denise Mayes, Jason Kropp, Natalie Goltz, Bennett Carter, Johan Sebastian Basuki, Bradley Maurer, Gary Baker, James R. Wright, David Rusch, Rebecca Ahn, Brian C. Austad, Kris Depew, Joseph Helble, Jie Ge, Jason J. Piotrowski, Marlene R. Booth, Julian Adams, Mark Douglas, Steven G. Wong, Laila Kott, James R. Porter, Geoff E. Sylvester, Dumitru Ionescu, Jennifer R. Porter, Brendan Arsenault
Publikováno v:
Drug Development Research. 71:429-438
IPI-504 (retaspimycin hydrochloride) is an Hsp90 inhibitor that is the subject of multiple clinical trials for the treatment of cancer. IPI-504 is an aqueous soluble (>200 mg/ml) hydroquinone hydrochloride salt of 17-(allylamino)-17-demethoxygeldanam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1542e76e86b5ffd5bfe160834ae9e695
https://doi.org/10.1002/ddr.20383
https://doi.org/10.1002/ddr.20383
Autor:
Matthew Campbell, Caroline N. Woodward, Jens Sydor, Alfredo C. Castro, James R. Porter, Margaret A. Read, Kerrie Faia, Kerry White, Martin R. Tremblay, Jill Cushing, Julian Adams, Lin-Chen Yu, Mark L. Behnke, Jennifer Hoyt, Vito J. Palombella, Karen McGovern, Somarajan J. Nair, Jeffrey K. Tong, Margit Hagel, Marta Nevalainen, Louis Grenier, Michael Foley
Publikováno v:
Journal of Medicinal Chemistry. 51:6646-6649
Herein is reported the synthesis of a novel class of hedgehog antagonists derived from cyclopamine. The acid sensitive D-ring of cyclopamine was homologated utilizing a sequence of chemoselective cyclopropanation and stereoselective acid-catalyzed re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d0752adc424ed0f2bb4f871b70a4f4
https://doi.org/10.1021/jm8008508
https://doi.org/10.1021/jm8008508