Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Louis, Gevirtzman"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1011049 (2023)
Single cell ATAC-seq (scATAC-seq) enables the mapping of regulatory elements in fine-grained cell types. Despite this advance, analysis of the resulting data is challenging, and large scale scATAC-seq data are difficult to obtain and expensive to gen
Externí odkaz:
https://doaj.org/article/f9d6061a0afb4e61be049f68830cdb19
Autor:
Abbas Ghaddar, Erick Armingol, Chau Huynh, Louis Gevirtzman, Nathan E. Lewis, Robert Waterston, Eyleen J. O’Rourke
Publikováno v:
Science advances, vol 9, iss 25
SummaryAnimals are integrated organ systems composed of interacting cells whose structure and function are in turn defined by their active genes. Understanding what distinguishes physiological and disease states therefore requires systemic knowledge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058cddee183269a45424381e1a4b1e04
https://escholarship.org/uc/item/9n93r4kt
https://escholarship.org/uc/item/9n93r4kt
Autor:
Jay Shendure, Timothy Durham, William Stafford Noble, Louis Gevirtzman, Darren A. Cusanovich, Olubusayo Bolonduro, Riza M. Daza, Robert H. Waterston
Publikováno v:
Genome Research. 31:1952-1969
Recently developed single-cell technologies allow researchers to characterize cell states at ever greater resolution and scale. Caenorhabditis elegans is a particularly tractable system for studying development, and recent single-cell RNA-seq studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe8da6dae0b90b92a635ce93b371681
https://doi.org/10.1101/gr.271791.120
https://doi.org/10.1101/gr.271791.120
Publikováno v:
Genome Research. 29:1036-1045
We have used RNA-seq in Caenorhabditis elegans to produce transcription profiles for seven specific embryonic cell populations from gastrulation to the onset of terminal differentiation. The expression data for these seven cell populations, covering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::874a2338b6a945fb8e8a29cbc6c81381
https://doi.org/10.1101/gr.243394.118
https://doi.org/10.1101/gr.243394.118
Autor:
Kevin P. White, Mark Gerstein, Jiahao Gao, Alec Victorsen, Jinrui Xu, Haneen N. Ammouri, Valerie Reinke, Louis Gevirtzman, Fabio C. P. Navarro, Michelle M. Kudron, Robert H. Waterston
Publikováno v:
Nucleic Acids Research
Chromatin immunoprecipitation (IP) followed by sequencing (ChIP-seq) is the gold standard to detect genome-wide DNA-protein binding. The binding sites of transcription factors facilitate many biological studies. Of emerging concern is the abundance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd13c0ced910abb4fec09ba5036a64bd
https://pubmed.ncbi.nlm.nih.gov/33347581
https://pubmed.ncbi.nlm.nih.gov/33347581
Autor:
Timothy J, Durham, Riza M, Daza, Louis, Gevirtzman, Darren A, Cusanovich, Olubusayo, Bolonduro, William Stafford, Noble, Jay, Shendure, Robert H, Waterston
Publikováno v:
Genome Res
Recently developed single-cell technologies allow researchers to characterize cell states at ever greater resolution and scale. Caenorhabditis elegans is a particularly tractable system for studying development, and recent single-cell RNA-seq studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a38e9eb7c2ccb211a3c9a9b255ba2bcf
https://pubmed.ncbi.nlm.nih.gov/33888511
https://pubmed.ncbi.nlm.nih.gov/33888511
Autor:
LaDeana W. Hillier, Mitch Corson, Martha Wall, D. Vafeados, Alec Victorsen, Robert H. Waterston, Robert Terrell, William W. Fisher, Susan E. Celniker, David Steffen, Matt Kirkey, Ann S. Hammonds, Koon-Kiu Yan, Mark Gerstein, Haneen N. Ammouri, Swapna Samanta, Samantha Seabrook-Sturgis, Madhura Kadaba, Lijia Ma, Soo Park, Jeffery Gersch, Matt Szynkarek, Michelle M. Kudron, Mei Han, Valerie Reinke, Kevin P. White, Jennifer L. Moran, Timothy Durham, Louis Gevirtzman, Jinrui Xu, Jaeda Patton, Nader Jameel
Publikováno v:
Genetics. 208:937-949
The model organism Encylopedia of Regulatory Elements (modERN) project was designed to generate genome-wide binding profiles for the majority of transcription... To develop a catalog of regulatory sites in two major model organisms, Drosophila melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85e8febc2794113aef533cfcd00cd9a
https://doi.org/10.1534/genetics.117.300657
https://doi.org/10.1534/genetics.117.300657
Autor:
Dominique Rasoloson, Matthew R. Wallenfang, Nadin Memar, Robert H. Waterston, Geraldine Seydoux, Mark L. Edgley, Vinci Au, John Yochem, Calvin Mok, Bruce Bowerman, Louis Gevirtzman, Joshua B. Lowry, Ralf Schnabel, Donald G. Moerman, Owen Thompson
Publikováno v:
Genetics. 207:447-463
Mutants remain a powerful means for dissecting gene function in model organisms such as Caenorhabditis elegans. Massively parallel sequencing has simplified the detection of variants after mutagenesis but determining precisely which change is respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aff6803215cfc80973d0ee82863da82
https://doi.org/10.1534/genetics.117.300179
https://doi.org/10.1534/genetics.117.300179
Publikováno v:
Genome research. 29(6)
We have used RNA-seq in Caenorhabditis elegans to produce transcription profiles for seven specific embryonic cell populations from gastrulation to the onset of terminal differentiation. The expression data for these seven cell populations, covering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbd1acfc69dab612a25c3b0ecd0d6ec0
https://pubmed.ncbi.nlm.nih.gov/31123079
https://pubmed.ncbi.nlm.nih.gov/31123079
Autor:
Michelle M, Kudron, Alec, Victorsen, Louis, Gevirtzman, LaDeana W, Hillier, William W, Fisher, Dionne, Vafeados, Matt, Kirkey, Ann S, Hammonds, Jeffery, Gersch, Haneen, Ammouri, Martha L, Wall, Jennifer, Moran, David, Steffen, Matt, Szynkarek, Samantha, Seabrook-Sturgis, Nader, Jameel, Madhura, Kadaba, Jaeda, Patton, Robert, Terrell, Mitch, Corson, Timothy J, Durham, Soo, Park, Swapna, Samanta, Mei, Han, Jinrui, Xu, Koon-Kiu, Yan, Susan E, Celniker, Kevin P, White, Lijia, Ma, Mark, Gerstein, Valerie, Reinke, Robert H, Waterston
Publikováno v:
Genetics. 208(3)
To develop a catalog of regulatory sites in two major model organisms, Drosophila melanogaster and Caenorhabditis elegans, the modERN (model organism Encyclopedia of Regulatory Networks) consortium has systematically assayed the binding sites of tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aef49ddc82c39bdad95be1f4988d2ad3
https://pubmed.ncbi.nlm.nih.gov/29284660
https://pubmed.ncbi.nlm.nih.gov/29284660