Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Louis, Gendron"'
Autor:
Stéphane Potvin, Matthieu Vincenot, Lounès Haroune, Charles-Édouard Giguère, Louis Gendron, Guillaume Léonard, Serge Marchand
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Our laboratory previously developed a method for assessing experimentally induced pain perception through a 2-min constant heat pain stimulation. However, the traditional analysis relying on group means struggles to interpret the considerabl
Externí odkaz:
https://doaj.org/article/deecf37b98f14287bade38717cfe7559
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307556 (2024)
BackgroundQuantitative sensory tests (QST) are frequently used to explore alterations in somatosensory systems. Static and dynamic QST like pain threshold and temporal summation (TS) and conditioned pain modulation (CPM) are commonly used to evaluate
Externí odkaz:
https://doaj.org/article/0c1a399c7b334458997d0f410591b3d6
Autor:
Monica Sean, Alexia Coulombe-Lévêque, Matthieu Vincenot, Marylie Martel, Louis Gendron, Serge Marchand, Guillaume Léonard
Publikováno v:
Canadian Journal of Pain, Vol 5, Iss 1, Pp 56-65 (2021)
Background: Temporal summation and conditioned pain modulation (CPM) can be measured using a thermode and cold pressor test (CPTest). Unfortunately, these complex and expensive tools are ill-suited for routine clinical assessments. Aims: We aimed to
Externí odkaz:
https://doaj.org/article/955b83cd2a844adba4c94406707b9c39
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Due to their low expression levels, complex multi-pass transmembrane structure, and the current lack of highly specific antibodies, the assessment of endogenous G protein-coupled receptors (GPCRs) remains challenging. While most of the research regar
Externí odkaz:
https://doaj.org/article/b51269a28d5242bfa4a983b804d44a6b
Autor:
Monica Sean, Alexia Coulombe-Lévêque, Martine Bordeleau, Matthieu Vincenot, Louis Gendron, Serge Marchand, Guillaume Léonard
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
Temporal summation of pain (TSP) and conditioned pain modulation (CPM) can be measured using a thermode and a cold pressor test (CPT). Unfortunately, these tools are complex, expensive, and are ill-suited for routine clinical assessments. Building on
Externí odkaz:
https://doaj.org/article/e91f19e8110c4f409381d034460086da
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Nowadays, pain represents one of the most important societal burdens. Current treatments are, however, too often ineffective and/or accompanied by debilitating unwanted effects for patients dealing with chronic pain. Indeed, the prototypical opioid m
Externí odkaz:
https://doaj.org/article/89264f6496094a869c30e9e17f237cd0
Autor:
Khaled Abdallah, Francis Nadeau, Francis Bergeron, Sylvie Blouin, Véronique Blais, Kelly M. Bradbury, Christine L. Lavoie, Jean-Luc Parent, Louis Gendron
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Genetically-modified animal models have significantly increased our understanding of the complex central nervous system circuits. Among these models, inducible transgenic mice whose specific gene expression can be modulated through a Cre rec
Externí odkaz:
https://doaj.org/article/5eeb6fec159e4ba2ad1fe5c9dd194b56
Autor:
Marjan Gharagozloo, Shaimaa Mahmoud, Camille Simard, Kenzo Yamamoto, Diwakar Bobbala, Subburaj Ilangumaran, Matthew D Smith, Albert Lamontagne, Samir Jarjoura, Jean-Bernard Denault, Véronique Blais, Louis Gendron, Carles Vilariño-Güell, A Dessa Sadovnick, Jenny P Ting, Peter A Calabresi, Abdelaziz Amrani, Denis Gris
Publikováno v:
PLoS Biology, Vol 17, Iss 9, p e3000451 (2019)
Nucleotide-binding, leucine-rich repeat containing X1 (NLRX1) is a mitochondria-located innate immune sensor that inhibits major pro-inflammatory pathways such as type I interferon and nuclear factor-κB signaling. We generated a novel, spontaneous,
Externí odkaz:
https://doaj.org/article/58ac34a8bf8e4f90ae99175810c13f3c
Publikováno v:
European Journal of Neuroscience. 56:4031-4044
Primary afferents are responsible for transmitting signals produced by noxious stimuli from the periphery to the spinal cord. Mu and delta opioid receptors (MOP and DOP) have analgesic properties and are highly expressed in dorsal root ganglia (DRG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd7e86ad567866e82a6dc0294e5ac31
https://doi.org/10.1111/ejn.15733
https://doi.org/10.1111/ejn.15733
Autor:
Johannie Audet, Sirine Yassine, Charly G Lecomte, Stephen Mari, Soucy Félix, Morency Caroline, Angèle N Merlet, Jonathan Harnie, Claudie Beaulieu, Louis Gendron, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon
Publikováno v:
bioRxiv
Spinal sensorimotor circuits interact with supraspinal and peripheral inputs to generate quadrupedal locomotion. Ascending and descending spinal pathways ensure coordination between the fore-and hindlimbs. Spinal cord injury disrupts these pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f85052d74151e15169372841b73b593
https://doi.org/10.1101/2023.03.23.533936
https://doi.org/10.1101/2023.03.23.533936
