Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Louis, AA"'
Autor:
Mohanty, V, Louis, AA
Publikováno v:
Physical Review E. 107
Across many problems in science and engineering, it is important to consider how much the output of a given system changes due to perturbations of the input. Here, we investigate the glassy phase of ± J spin glasses at zero temperature by calculatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d712c4c97d5f393bf35fa96c73f75f4
https://doi.org/10.1103/physreve.107.014126
https://doi.org/10.1103/physreve.107.014126
Predicting phenotype transition probabilities via conditional algorithmic probability approximations
Peer reviewed: True
Unravelling the structure of genotype-phenotype (GP) maps is an important problem in biology. Recently, arguments inspired by algorithmic information theory (AIT) and Kolmogorov complexity have been invoked to uncover simplic
Unravelling the structure of genotype-phenotype (GP) maps is an important problem in biology. Recently, arguments inspired by algorithmic information theory (AIT) and Kolmogorov complexity have been invoked to uncover simplic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e612facb68cbc1bb14cebe5755058769
https://doi.org/10.1101/2022.09.21.508902
https://doi.org/10.1101/2022.09.21.508902
Publikováno v:
arXiv
The design space for a self-assembled multicomponent objects ranges from a solution in which every building block is unique to one with the minimum number of distinct building blocks that unambiguously define the target structure. Using a novel pipel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ac21246be72c22111c2f1496099a46
Overparameterised deep neural networks (DNNs) are highly expressive and so can, in principle, generate almost any function that fits a training dataset with zero error. The vast majority of these functions will perform poorly on unseen data, and yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c79b10ac78850459ca1eff199ec2774
https://ora.ox.ac.uk/objects/uuid:632426cc-9a46-4a06-af4c-7b2d392bce12
https://ora.ox.ac.uk/objects/uuid:632426cc-9a46-4a06-af4c-7b2d392bce12
Autor:
Matek, C, Ouldridge, TE, Doye, JP, Louis, AA, Matek, Christian, Ouldridge, Thomas E., Doye, Jonathan P.K., Louis, Ard A.
We predict a novel conformational regime for DNA, where denaturation bubbles form at the tips of plectonemes, and study its properties using coarse-grained simulations. For negative supercoiling, this regime lies between bubble-dominated and plectone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5bd3ecc26953786176bb3a7a6ef013df
https://doi.org/10.1038/srep07655
https://doi.org/10.1038/srep07655
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 3, p e1004773 (2016)
PLoS Computational Biology
PLoS Computational Biology
Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to share characteristics than expected from random chance. Such genetic correlations should strongly influence evolutionary dynamics. We explore and quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aeb8aa034debb717c74e98402f27602
http://europepmc.org/articles/PMC4777517?pdf=render
http://europepmc.org/articles/PMC4777517?pdf=render
Publikováno v:
Scientific Reports
Biological information is not only stored in the digital chemical sequence of double helical DNA, but is also encoded in the mechanical properties of the DNA strands, which can influence biochemical processes involving its readout. For example, loop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155a4c3f1b64780523587f85c9b626f0
http://europepmc.org/articles/PMC5224516
http://europepmc.org/articles/PMC5224516
The effect of secondary structure on DNA duplex formation is poorly understood. We use a coarse-grained model of DNA to show that specific 3- and 4-base pair hairpins reduce hybridization rates by factors of 2 and 10 respectively, in good agreement w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f80aa768316053274dc2193f93f6b4
Autor:
Hanekamp, Manon N, Mazer, Petra, van der Cammen-van Zijp, Monique HM, van Kessel-Feddema, Boudien JM, Nijhuis-van der Sanden, Maria WG, Knuijt, Simone, Zegers-Verstraeten, Jessica LA, Gischler, Saskia J, Tibboel, Dick, Kollée, Louis AA
Publikováno v:
Critical Care
Introduction Extracorporeal membrane oxygenation (ECMO) is a supportive cardiopulmonary bypass technique for babies with acute reversible cardiorespiratory failure. We assessed morbidity in ECMO survivors at the age of five years, when they start pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8edd65ba4d695899e9c2658bc2b07f82
https://pubmed.ncbi.nlm.nih.gov/18320939
https://pubmed.ncbi.nlm.nih.gov/18320939
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