Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Louie Shou"'
Autor:
Rick G. Schnellmann, Ruili Huang, Matias S. Attene-Ramos, Louie Shou, Gyda C. Beeson, Christopher P. Austin, Raymond R. Tice, Craig Beeson, Kristine L. Witt, Srilatha Sakamuru, Menghang Xia
Publikováno v:
Chemical Research in Toxicology. 26:1323-1332
A goal of the Tox21 program is to transit toxicity testing from traditional in vivo models to in vitro assays that assess how chemicals affect cellular responses and toxicity pathways. A critical contribution of the NIH Chemical Genomics center (NCGC
Autor:
Noel Southall, Menghang Xia, Daniel Beacham, Louie Shou, Yong Zhao, Christopher P. Austin, Elizabeth Hooten, Sampada A. Shahane, Wei Zheng, Ruili Huang, Steve Titus
Publikováno v:
Analytical Biochemistry. 394:30-38
Long QT syndrome, either inherited or acquired from drug treatments, can result in ventricular arrhythmia (torsade de pointes) and sudden death. Human ether-a-go-go-related gene (hERG) channel inhibition by drugs is now recognized as a common reason
Autor:
Menghang Xia, Louie Shou, Jianming Lu, Christopher P. Austin, Min Shen, Matias S. Attene-Ramos, Raymond R. Tice, Xiao Li, Srilatha Sakamuru, Ruili Huang
Publikováno v:
Physiological genomics. 44(9)
Decreases in mitochondrial membrane potential (MMP) have been associated with mitochondrial dysfunction that could lead to cell death. The MMP is generated by an electrochemical gradient via the mitochondrial electron transport chain coupled to a ser