Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Louesa R. Akin"'
Autor:
Shohei Koide, Allan Joaquim Lamontanara, John Wojcik, Oliver Hantschel, Louesa R. Akin, Grzegorz J. Grabe, Barbara Gerig, Akiko Koide
Publikováno v:
Journal of Biological Chemistry. 291:8836-8847
Bcr-Abl is a constitutively active kinase that causes chronic myelogenous leukemia. We have shown that a tandem fusion of two designed binding proteins, termed monobodies, directed to the interaction interface between the Src homology 2 (SH2) and kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d16b8fd31bd70d1970ba68b0d7fbce
https://doi.org/10.1074/jbc.m115.707901
https://doi.org/10.1074/jbc.m115.707901
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:587-595
When experimental protein NMR data are too sparse to apply traditional structure determination techniques, de novo protein structure prediction methods can be leveraged. Here, we describe the incorporation of NMR restraints into the protein structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd87efe3840a6a1a08c2e2c14815d431
https://doi.org/10.1002/prot.24427
https://doi.org/10.1002/prot.24427
Autor:
Neil L. Kelleher, Takamitsu Hattori, Kohei Kurosawa, Irina Dementieva, Brian D. Strahl, Darson Lai, Alexander J. Ruthenburg, Sherwin P. Montaño, Kalina M. Świst-Rosowska, Akiko Koide, Krzysztof Krajewski, Shohei Koide, Adrian T. Grzybowski, Louesa R. Akin, Yupeng Zheng
Antibodies have a well-established modular architecture wherein the antigen-binding site residing in the antigen-binding fragment (Fab or Fv) is an autonomous and complete unit for antigen recognition. Here, we describe antibodies departing from this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d123fef2e4818b7cea2d5d20788169
Autor:
Brian E, Weiner, Nathan, Alexander, Louesa R, Akin, Nils, Woetzel, Mert, Karakas, Jens, Meiler
Publikováno v:
Proteins. 82(4)
When experimental protein NMR data are too sparse to apply traditional structure determination techniques, de novo protein structure prediction methods can be leveraged. Here, we describe the incorporation of NMR restraints into the protein structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4c6eb1da2a8a0038de419144ffcbd50
https://pubmed.ncbi.nlm.nih.gov/24123100
https://pubmed.ncbi.nlm.nih.gov/24123100