Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Loubna Mhamdi"'
Autor:
Michael R. Paillasse, Philippe de Medina, Guillaume Amouroux, Loubna Mhamdi, Marc Poirot, Sandrine Silvente-Poirot
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2203-2211 (2009)
Several studies indicate that cholesterol esterification is deregulated in cancers. The present study aimed to characterize the role of cholesterol esterification in proliferation and invasion of two tumor cells expressing an activated cholecystokini
Externí odkaz:
https://doaj.org/article/201f055a2fd3429d8913d0b637d58c79
Autor:
Sandrine Silvente-Poirot, Marc Poirot, Michel Record, Dominique Goudounèche, Isabelle Fourquaux, François Tercé, Justine Bertrand-Michel, Loubna Mhamdi, Nadia Boubekeur, Philippe de Medina, Bruno Payré
Supplementary Fig. S2 from Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8feb487db7771bbf43b5107364ac6c88
https://doi.org/10.1158/1535-7163.22483844.v1
https://doi.org/10.1158/1535-7163.22483844.v1
Autor:
Sandrine Silvente-Poirot, Marc Poirot, Michel Record, Dominique Goudounèche, Isabelle Fourquaux, François Tercé, Justine Bertrand-Michel, Loubna Mhamdi, Nadia Boubekeur, Philippe de Medina, Bruno Payré
The microsomal antiestrogen-binding site (AEBS) is a high-affinity membranous binding site for the antitumor drug tamoxifen that selectively binds diphenylmethane derivatives of tamoxifen such as PBPE and mediates their antiproliferative properties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f934b63c836cd9a3c994391b1d01ebb
https://doi.org/10.1158/1535-7163.c.6531248
https://doi.org/10.1158/1535-7163.c.6531248
Autor:
Stéphan Vagner, Magali Lacroix-Triki, Florence Dalenc, Henri Roché, Jean-Pierre Delord, Gilles Favre, Li Fan, Loubna Mhamdi, Samantha Beck, Anne Cammas, Sandra Pierredon, Thomas Filleron, Ben Allal, Yann Bergé, Pierre Zindy
Supplementary Tables 1-2, Figures 1-2, Material and Methods from Formation of the eIF4F Translation–Initiation Complex Determines Sensitivity to Anticancer Drugs Targeting the EGFR and HER2 Receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebe60670c35272bf63a28ab6bdf5742
https://doi.org/10.1158/0008-5472.22387704.v1
https://doi.org/10.1158/0008-5472.22387704.v1
Autor:
Carine Valle, Gaëtan MacGrogan, Loubna Mhamdi, Noémie Thébault, Sabrina Croce, Laetitia Mayeur, Frédéric Guyon, Flora Rebier, Tom Lesluyes, Isabelle Soubeyran, Jean-Christophe Noel, Camille Chakiba, Gaëlle Pérot, Denis Querleu, Anne Floquet, Sophie Le Guellec, Mojgan Devouassoux-Shisheboran, Eberhard Stoeckle, Frédéric Chibon, Quitterie Fontanges
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(4)
Purpose: Uterine leiomyosarcoma, which accounts for 7% of all soft-tissue sarcomas and 1%–3% of all uterine malignancies, is an aggressive tumor responsible for a significant proportion of uterine cancer–related deaths. While Federation Internati
Autor:
Loubna Mhamdi, Maud Voisin, Camille Franchet, Emmanuel Noguer, Léonor Chaltiel, Marc Poirot, Elodie Bacquié, Philippe Rochaix, Arnaud Mallinger, Aurélie Mougel, Thomas Filleron, Chiara Zerbinati, Vincent Cavaillès, Magali Lacroix-Triki, Julie Leignadier, Frédéric Lopez, Nizar Serhan, Sandrine Silvente-Poirot, Luigi Iuliano, Emilie Huc-Claustre, Gregory Segala, Talal Al Saati, Laetitia Ligat, Regis Soules, Michel Record, Raphaëlle Duprez-Paumier, Florence Dalenc, Philippe de Medina
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
International audience; Breast cancer (BC) remains the primary cause of death from cancer among women worldwide. Cholesterol-5,6-epoxide (5,6-EC) metabolism is deregulated in BC but the molecular origin of this is unknown. Here, we have identified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7379b46392db086e832aa7d1255938
https://europepmc.org/articles/PMC5676900/
https://europepmc.org/articles/PMC5676900/
Autor:
Carine Valle, Tatiana Kempowsky-Hamon, Jean-Marie François, Gilles Favre, Delphine Labourdette, Sophie Lamarre, Magali Lacroix-Triki, Marie-Véronique Le Lann, Loubna Mhamdi, Lidwine Trouilh, Lyamine Hedjazi, Thomas Filleron, Florence Dalenc, Véronique Anton-Leberre, Laurence Roger
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2015, 8 (3), ⟨10.1186/s12920-015-0077-1⟩
BMC Medical Genomics, BioMed Central, 2015, 8 (1)
BMC Medical Genomics, 2015, 8 (3), ⟨10.1186/s12920-015-0077-1⟩
BMC Medical Genomics (8), . (2015)
BMC Medical Genomics, BioMed Central, 2015, 8 (3), ⟨10.1186/s12920-015-0077-1⟩
BMC Medical Genomics, BioMed Central, 2015, 8 (1)
BMC Medical Genomics, 2015, 8 (3), ⟨10.1186/s12920-015-0077-1⟩
BMC Medical Genomics (8), . (2015)
Background Personalized medicine has become a priority in breast cancer patient management. In addition to the routinely used clinicopathological characteristics, clinicians will have to face an increasing amount of data derived from tumor molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e97bfbc1d19f2d0801718819c9c5254
https://hal.archives-ouvertes.fr/hal-01849444/file/document.pdf
https://hal.archives-ouvertes.fr/hal-01849444/file/document.pdf
Autor:
Marc Poirot, Guillaume Amouroux, Loubna Mhamdi, Sandrine Silvente-Poirot, Michael R. Paillasse, Philippe de Medina
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2203-2211 (2009)
Journal of Lipid Research
Journal of Lipid Research, 2009, 50 (11), pp.2203-11. ⟨10.1194/jlr.M800668-JLR200⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2009, 50 (11), pp.2203-11. ⟨10.1194/jlr.M800668-JLR200⟩
Journal of Lipid Research
Journal of Lipid Research, 2009, 50 (11), pp.2203-11. ⟨10.1194/jlr.M800668-JLR200⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2009, 50 (11), pp.2203-11. ⟨10.1194/jlr.M800668-JLR200⟩
International audience; Several studies indicate that cholesterol esterification is deregulated in cancers. The present study aimed to characterize the role of cholesterol esterification in proliferation and invasion of two tumor cells expressing an
Autor:
Philippe de Medina, Bruce D. Hammock, Marc Poirot, Maud Voisin, Michael R. Paillasse, Gregory Segala, Loubna Mhamdi, Frederic Pont, Thomas Filleron, Florence Dalenc, Talal Al Saati, Sandrine Silvente-Poirot, Magali Lacroix-Triki, Christophe Morisseau
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2013, 4, pp.1840. ⟨10.1038/ncomms2835⟩
Nature Communications, 2013, 4, pp.1840. ⟨10.1038/ncomms2835⟩
Nature Communications, Nature Publishing Group, 2013, 4, pp.1840. ⟨10.1038/ncomms2835⟩
Nature Communications, 2013, 4, pp.1840. ⟨10.1038/ncomms2835⟩
We previously synthesized dendrogenin A and hypothesized that it could be a natural metabolite occurring in mammals. Here we explore this hypothesis and report the discovery of dendrogenin A in mammalian tissues and normal cells as an enzymatic produ
Autor:
Anne Cammas, Loubna Mhamdi, Jean Pierre Delord, Sandra Pierredon, Yann Berge, Thomas Filleron, Pierre Zindy, Li Fan, Magali Lacroix-Triki, Henri Roché, Samantha Beck, Gilles Favre, Stéphan Vagner, Ben Allal, Florence Dalenc
Publikováno v:
Cancer research. 71(12)
Elucidating how cancer cells respond to antagonists of HER receptor family members is critical to understanding mechanisms of therapeutic resistance that arise in patients. In large part, resistance to such agents appears to arise from deregulation o