Developmental and housekeeping transcriptional programs display distinct modes of enhancer-enhancer cooperativity in Drosophila.

Autor: Loubiere V; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., de Almeida BP; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria., Pagani M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Stark A; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. stark@starklab.org.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria. stark@starklab.org.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 03; Vol. 15 (1), pp. 8584. Date of Electronic Publication: 2024 Oct 03.

Sustained inactivation of the Polycomb PRC1 complex induces DNA repair defects and genomic instability in epigenetic tumors.

Autor: Rawal CC; Department of Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA, 90089, USA., Loubiere V; Institute of Human Genetics, CNRS, University of Montpellier, Montpellier, France.; Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria., Butova NL; Department of Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA, 90089, USA., Gracia J; Institute of Human Genetics, CNRS, University of Montpellier, Montpellier, France., Parreno V; Institute of Human Genetics, CNRS, University of Montpellier, Montpellier, France., Merigliano C; Department of Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA, 90089, USA., Martinez AM; Institute of Human Genetics, CNRS, University of Montpellier, Montpellier, France. anne-marie.martinez@igh.cnrs.fr., Cavalli G; Institute of Human Genetics, CNRS, University of Montpellier, Montpellier, France. giacomo.cavalli@igh.cnrs.fr., Chiolo I; Department of Molecular and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA, 90089, USA. chiolo@usc.edu.

Publikováno v: Histochemistry and cell biology [Histochem Cell Biol] 2024 Jul; Vol. 162 (1-2), pp. 133-147. Date of Electronic Publication: 2024 Jun 18.

CBP and Gcn5 drive zygotic genome activation independently of their catalytic activity.

Autor: Ciabrelli F; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany., Rabbani L; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany., Cardamone F; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.; University of Freiburg, Faculty of Biology, Freiburg im Breisgau, Germany., Zenk F; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany., Löser E; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany., Schächtle MA; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany., Mazina M; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany., Loubiere V; Institute of Molecular Pathology, Wien, Austria., Iovino N; Department of Chromatin Regulation, Max Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.

Publikováno v: Science advances [Sci Adv] 2023 Apr 21; Vol. 9 (16), pp. eadf2687. Date of Electronic Publication: 2023 Apr 21.

A shared ancient enhancer element differentially regulates the bric-a-brac tandem gene duplicates in the developing Drosophila leg.

Autor: Bourbon HG; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France., Benetah MH; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France., Guillou E; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France., Mojica-Vazquez LH; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France., Baanannou A; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France., Bernat-Fabre S; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France., Loubiere V; Institute of Human Genetics, University of Montpellier, CNRS Montpellier, France., Bantignies F; Institute of Human Genetics, University of Montpellier, CNRS Montpellier, France., Cavalli G; Institute of Human Genetics, University of Montpellier, CNRS Montpellier, France., Boube M; Center for Integrative Biology, Molecular Cellular and Developmental (MCD) Biology Unit, Federal University of Toulouse, Toulouse, France.

Publikováno v: PLoS genetics [PLoS Genet] 2022 Mar 16; Vol. 18 (3), pp. e1010083. Date of Electronic Publication: 2022 Mar 16 (Print Publication: 2022).

4D Genome Rewiring during Oncogene-Induced and Replicative Senescence.

Autor: Sati S; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France., Bonev B; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France., Szabo Q; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France., Jost D; Univ Grenoble Alpes, CNRS, Grenoble INP, TIMC-IMAG, 38000 Grenoble, France., Bensadoun P; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France., Serra F; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain., Loubiere V; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France., Papadopoulos GL; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France., Rivera-Mulia JC; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55455, USA., Fritsch L; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France., Bouret P; Unit of Chromosomal Genetics and Chromostem Research Platform, CHU, Montpellier, France., Castillo D; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain., Gelpi JL; Barcelona Supercomputing Center, Barcelona, Spain; Department of Biochemistry and Molecular Biomedicine, University of Barcelona, Barcelona, Spain., Orozco M; Department of Biochemistry and Molecular Biomedicine, University of Barcelona, Barcelona, Spain; Institute for Research in Biomedicine, the Barcelona Institute of Science and Technology, Barcelona, Spain., Vaillant C; Laboratoire de Physique (UMR CNRS 5672), ENS de Lyon, Lyon, France., Pellestor F; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France; Unit of Chromosomal Genetics and Chromostem Research Platform, CHU, Montpellier, France., Bantignies F; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France., Marti-Renom MA; CNAG-CRG, Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain; Centre for Genomic Regulation, The Barcelona Institute for Science and Technology, Carrer del Doctor Aiguader 88, Barcelona 08003, Spain; Pompeu Fabra University, Doctor Aiguader 88, Barcelona 08003, Spain; CREA, PgLluís Companys 23, 08010 Barcelona, Spain., Gilbert DM; Department of Biological Science and Center for Genomics and Personalized Medicine, Florida State University, Tallahassee, FL 32306, USA., Lemaitre JM; Institute for Regenerative Medicine and Biotherapy, Univ Montpellier, INSERM UMR1183, F-34295 Montpellier, France; CHRU de Montpellier, Montpellier, France. Electronic address: jean-marc.lemaitre@inserm.fr., Cavalli G; Institute of Human Genetics, UMR 9002, CNRS and University of Montpellier, Montpellier, France. Electronic address: giacomo.cavalli@igh.cnrs.fr.

Publikováno v: Molecular cell [Mol Cell] 2020 May 07; Vol. 78 (3), pp. 522-538.e9. Date of Electronic Publication: 2020 Mar 26.