Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Lou Ellis"'
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Akademický článek
Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection.
Autor: Steve J Webster, Sven Brode, Lou Ellis, Timothy J Fitzmaurice, Matthew J Elder, Nelson O Gekara, Panagiotis Tourlomousis, Clare Bryant, Simon Clare, Ronnie Chee, Hill J S Gaston, Jane C Goodall
Publikováno v: PLoS Pathogens, Vol 13, Iss 6, p e1006383 (2017)
The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between infectious and non-infectious insult to prevent inappropriate inflammation. Using the impo
Externí odkaz: https://doaj.org/article/cc7ab21c35704bf99075bec68f1688a5
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4
Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection
Autor: Steve J, Webster, Sven, Brode, Lou, Ellis, Timothy J, Fitzmaurice, Matthew J, Elder, Nelson O, Gekara, Panagiotis, Tourlomousis, Clare, Bryant, Simon, Clare, Ronnie, Chee, Hill J S, Gaston, Jane C, Goodall
Publikováno v: PLoS Pathogens
The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between infectious and non-infectious insult to prevent inappropriate inflammation. Using the impo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d607aaade192086e743ae6844fad9ce
https://pubmed.ncbi.nlm.nih.gov/28570638
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5
IRE1α mediates PKR activation in response to Chlamydia trachomatis infection
Autor: Steve J, Webster, Lou, Ellis, Louise M, O'Brien, Beatrice, Tyrrell, Timothy J, Fitzmaurice, Matthew J, Elder, Simon, Clare, Ronnie, Chee, J S Hill, Gaston, Jane C, Goodall
Publikováno v: Microbes and Infection / Institut Pasteur
Protein kinase RNA activated (PKR) is a crucial mediator of anti-viral responses but is reported to be activated by multiple non-viral stimuli. However, mechanisms underlying PKR activation, particularly in response to bacterial infection, remain poo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9b548f37b6c8ccf22a9b99c1f95533a
https://pubmed.ncbi.nlm.nih.gov/27021640
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7
Spondylarthritis-associated and non–spondylarthritis-associated B27 subtypes differ in their dependence upon tapasin for surface expression and their incorporation into the peptide loading complex
Autor: J. S. Hill Gaston, Jane C. Goodall, Lou Ellis
Publikováno v: Arthritis & Rheumatism. 54:138-147
Objective B27 subtypes associated with susceptibility to ankylosing spondylitis (AS), and those reported not to be associated with AS, are found to differ in the amino acids that are known in other HLA class I molecules to alter the requirements for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b24305c4943a1b79b8c07ac44168c5
https://doi.org/10.1002/art.21552
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9
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
Autor: Changxin Wu, Jane C. Goodall, J. S. Hill Gaston, Yongsheng Zhang, Lou Ellis, Louise McNeill, Vladimir Saudek
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 107(41)
The endoplasmic reticulum (ER) stress response detects malfunctions in cellular physiology, and microbial pattern recognition receptors recognize external threats posed by infectious agents. This study has investigated whether proinflammatory cytokin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cd801ed0ff16f3340d717145eb1c11
https://pubmed.ncbi.nlm.nih.gov/20876114
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10
Does HLA-B27 influence the monocyte inflammatory response to lipopolysaccharide?
Autor: J. S. H. Gaston, Jane C. Goodall, Lou Ellis, Giles S.H. Yeo
Publikováno v: Rheumatology (Oxford, England). 46(2)
OBJECTIVES How human leucocyte antigen B27 (HLA-B27) contributes towards arthritis susceptibility is still unclear, but effects on the response to bacteria unrelated to the classical antigen presenting role of B27 have been suggested. This study inve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9733c4f0e7263e135d468e03e71f119a
https://pubmed.ncbi.nlm.nih.gov/16877465
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