Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lou Chupak"'
Autor:
Amy K Sheaffer, Min S Lee, Huilin Qi, Susan Chaniewski, Xiaofan Zheng, Glen A Farr, Kim Esposito, David Harden, Ming Lei, Liang Schweizer, Jacques Friborg, Michele Agler, Fiona McPhee, Robert Gentles, Brett R Beno, Lou Chupak, Stephen Mason
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0155909 (2016)
A phenotypic high-throughput cell culture screen was performed to identify compounds that prevented proliferation of the human Papilloma virus type 16 (HPV-16) transformed cell line Ca Ski. A series of quinoxaline compounds exemplified by Compound 1
Externí odkaz:
https://doaj.org/article/0b210787c3874e4696b86d353003b927
Autor:
Amy K. Sheaffer, Glen A. Farr, Min S. Lee, Lou Chupak, Liang Schweizer, Ming Lei, Stephen W. Mason, Kim Esposito, Susan Chaniewski, David G. Harden, Xiaofan Zheng, Brett R. Beno, Huilin Qi, Fiona McPhee, Michele Agler, Robert G. Gentles, Jacques Friborg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0155909 (2016)
PLoS ONE, Vol 11, Iss 6, p e0155909 (2016)
A phenotypic high-throughput cell culture screen was performed to identify compounds that prevented proliferation of the human Papilloma virus type 16 (HPV-16) transformed cell line Ca Ski. A series of quinoxaline compounds exemplified by Compound 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f38cd5ec3ffde81d78ca094fe46b94a
https://pubmed.ncbi.nlm.nih.gov/27280728
https://pubmed.ncbi.nlm.nih.gov/27280728
Autor:
J.V.N. Vara Prasad, Lou Chupak, Frederick E. Boyer, Michael Melnick, K. Gavardinas, M. Patterson, Susan Elizabeth Hagen, Qizhu Ding, Michael D. Huband, Karina Romero, Samarendra N. Maiti, Michael R. Dermyer, Takushi Kaneko, Wenhua Jiao, Xiujuan Wu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5392-5397
We describe a novel class of benzocycloheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation is discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1134004c091cca1490341c0fe6c4ae2
https://doi.org/10.1016/j.bmcl.2006.07.064
https://doi.org/10.1016/j.bmcl.2006.07.064
Autor:
Mark Edward Flanagan, Anne E. Hagen, Yue Shen, Dennis Girard, Barbara J. Kamicker, Lou Chupak, Steven M. Finegan, Takushi Kaneko, Usa Reilly, Bryan Li, Timothy J. Strelevitz, R. Scott Obach, Richard A. Buzon, Gregory G. Stone, Karl Granskog, John Schafer, Joanna P. Wolkowski, Thuy-Trinh Nguyen, Mark C. Noe, Donn G. Wishka, Michael J. Falcone, John P. O'Donnell, Thomas J. Dougherty, David A. Whipple, Ivy Medina, Magee Thomas Victor, Joel R. Hardink, Jianmin Sun, Michael D. Huband, Jennifer L. Liras, Sharon L. Ripp, Kathleen A. Farley, Michael J. Knickerbocker, Andrea Marra, A. Tait-Kamradt, Joseph Penzien, Daniel W. Widlicka, Alfin D. N. Vaz
Publikováno v:
Journal of medicinal chemistry. 52(23)
Respiratory tract bacterial strains are becoming increasingly resistant to currently marketed macrolide antibiotics. The current alternative telithromycin (1) from the newer ketolide class of macrolides addresses resistance but is hampered by serious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f9468b29a17cd7d16cc76cd44d63f5
https://pubmed.ncbi.nlm.nih.gov/19775168
https://pubmed.ncbi.nlm.nih.gov/19775168
Autor:
Amit S. Kalgutkar, Lou Chupak, James P. Driscoll, Joanna P. Wolkowski, Katherine P. Kornecki, John P. O'Donnell
Publikováno v:
Chemical research in toxicology. 20(10)
The hypothesis that the psychological side effects associated with the anesthetic phencyclidine (PCP) may be caused by irreversible binding of PCP or its reactive metabolite(s) to critical macromolecules in the brain has resulted in numerous in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ca270ce43f966e27370b2f867b3b65
https://pubmed.ncbi.nlm.nih.gov/17892269
https://pubmed.ncbi.nlm.nih.gov/17892269
Autor:
Thomas V. Magee, Sharon L. Ripp, Bryan Li, Richard A. Buzon, Lou Chupak, Thomas J. Dougherty, Steven M. Finegan, Dennis Girard, Anne E. Hagen, Michael J. Falcone, Kathleen A. Farley, Karl Granskog, Joel R. Hardink, Michael D. Huband, Barbara J. Kamicker, Takushi Kaneko, Michael J. Knickerbocker, Jennifer L. Liras, Andrea Marra, Ivy Medina
Publikováno v:
Journal of Medicinal Chemistry; Dec2009, Vol. 52 Issue 23, p7446-7457, 12p
Autor:
James P. Driscoll, Katherine Kornecki, Joanna P. Wolkowski, Lou Chupak, Amit S. Kalgutkar, John P. O’Donnell
Publikováno v:
Chemical Research in Toxicology; Sep2007, Vol. 20 Issue 10, p1488-1497, 10p