Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Lou Ann S Brown"'
Autor:
Theresa W Gauthier, Sowmya S Mohan, Teresa S Gross, Frank L Harris, David M Guidot, Lou Ann S Brown
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126552 (2015)
The accumulation of fatty acid ethyl esters (FAEEs) in meconium of term newborns has been described as one potential biomarker of maternal alcohol use during pregnancy. FAEEs accumulate in multiple alcohol-exposed fetal tissues and in the placenta. L
Externí odkaz:
https://doaj.org/article/2889b6e74a9649d992cf3ab33ae42b8f
Autor:
Obiamaka Obianyo, Yan Liang, Ellen L Burnham, Ashish Mehta, Youngja Park, Karan Uppal, Frank L Harris, Dean P Jones, Lou Ann S Brown
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129570 (2015)
An alcohol use disorder (AUD) is associated with an increased susceptibility to respiratory infection and injury and, upon hospitalization, higher mortality rates. Studies in model systems show effects of alcohol on mitochondrial function, lipid meta
Externí odkaz:
https://doaj.org/article/569780ad97844f038103aa902eac7a74
Autor:
Theresa W Gauthier, Sowmya S Mohan, Teresa S Gross, Frank L Harris, David M Guidot, Lou Ann S Brown
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136366 (2015)
Externí odkaz:
https://doaj.org/article/23e3b8f56d7242debe73bc50e0a89e3e
Autor:
Gerald B Lee, Eric B Brandt, Chang Xiao, Aaron M Gibson, Timothy D Le Cras, Lou Ann S Brown, Anne M Fitzpatrick, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60632 (2013)
Diesel exhaust particle (DEP) exposure enhances allergic inflammation and has been linked to the incidence of asthma. Oxidative stress on the thiol molecules cysteine (Cys) and glutathione (GSH) can promote inflammatory host responses. The effect of
Externí odkaz:
https://doaj.org/article/de105367b1c04fa7ae99ff3af3d59e37
Autor:
Meredith S Brown, Stefanie Ebelt Sarnat, Karen A DeMuth, Lou Ann S Brown, Denise R Whitlock, Shanae W Brown, Paige E Tolbert, Anne M Fitzpatrick
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37044 (2012)
While several studies suggest that traffic-related air pollutants are detrimental for respiratory health, few studies have examined relationships between residential proximity to a major roadway and asthma control in children. Furthermore, a major li
Externí odkaz:
https://doaj.org/article/9055618e544c4fc9a68d41eeef6638fa
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 137 (2024)
We previously reported that maternal alcohol use increased the risk of sepsis in premature and term newborns. In the neonatal mouse, fetal ethanol (ETOH) exposure depleted the antioxidant glutathione (GSH), which promoted alveolar macrophage (AM) imm
Externí odkaz:
https://doaj.org/article/bab29bd5fd2f4d029de9c2e35b8e4947
Publikováno v:
Alcohol. 106:30-43
Alcohol use disorders (AUD) cause alveolar macrophage (AM) immune dysfunction and increase risk of lung infections. Excessive alcohol use causes AM oxidative stress which impairs AM phagocytosis and pathogen clearance from the alveolar space. Alcohol
Autor:
Loretta Z. Reyes, Pamela D. Winterberg, Roshan Punnoose George, Michael Kelleman, Frank Harris, Hanjoong Jo, Lou Ann S. Brown, Claudia R. Morris
Publikováno v:
Nutrients; Volume 15; Issue 9; Pages: 2162
Cardiovascular disease is the leading cause of death in chronic kidney disease (CKD). Arginine, the endogenous precursor for nitric oxide synthesis, is produced in the kidneys. Arginine bioavailability contributes to endothelial and myocardial dysfun
Publikováno v:
J Immunol
Alcohol use disorders (AUD) increase susceptibility to respiratory infections by 2- to 4-fold in part because of impaired alveolar macrophage (AM) immune function. Alcohol causes AM oxidative stress, diminishing AM phagocytic capacity and clearance o
Publikováno v:
Experimental Biology and Medicine. :153537022311579
The lung microenvironment plays a crucial role in maintaining lung homeostasis as well as the initiation and resolution of both acute and chronic lung injury. Acute chest syndrome (ACS) is a complication of sickle cell disease (SCD) like acute lung i