Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Lou, Brundin"'
Autor:
Caroline Lindblad, Susanne Neumann, Sólrún Kolbeinsdóttir, Vasilios Zachariadis, Eric P. Thelin, Martin Enge, Sebastian Thams, Lou Brundin, Mikael Svensson
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Astrocytes respond to injury and disease through a process known as reactive astrogliosis, of which inflammatory signaling is one subset. This inflammatory response is heterogeneous with respect to the inductive stimuli and the af
Externí odkaz:
https://doaj.org/article/8b39860ab2eb440491d850d45468a07a
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 2, p 355 (2024)
Neuromyelitis optica spectrum disorder (NMOSD) is a rare immune-mediated relapsing-remitting disease of the central nervous system. The usage of rituximab, as relapse-preventive therapy, in NMOSD is common. We performed a single-center retrospective
Externí odkaz:
https://doaj.org/article/1a517f16e5d64a37b34f8d7e431294dc
Autor:
Lara Kular, Ewoud Ewing, Maria Needhamsen, Majid Pahlevan Kakhki, Ruxandra Covacu, David Gomez-Cabrero, Lou Brundin, Maja Jagodic
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1311-1330 (2022)
Multiple Sclerosis (MS), the leading cause of non-traumatic neurological disability in young adults, is a chronic inflammatory and neurodegenerative disease of the central nervous system (CNS). Due to the poor accessibility to the target organ, CNS-c
Externí odkaz:
https://doaj.org/article/c51728ccf3754d1c82a7db4b5d73b72f
Autor:
David O. Dias, Jannis Kalkitsas, Yildiz Kelahmetoglu, Cynthia P. Estrada, Jemal Tatarishvili, Daniel Holl, Linda Jansson, Shervin Banitalebi, Mahmood Amiry-Moghaddam, Aurélie Ernst, Hagen B. Huttner, Zaal Kokaia, Olle Lindvall, Lou Brundin, Jonas Frisén, Christian Göritz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Fibrotic scar tissue limits central nervous system regeneration. Here, Dias et al. show that fibrotic scarring is common in mice and humans, following distinct lesions to the adult brain and spinal cord, and derives from a discrete population of GLAS
Externí odkaz:
https://doaj.org/article/b2cf5ecacb394539a29e9965db99ad35
Autor:
Manuel Zeitelhofer, Milena Z. Adzemovic, Christine Moessinger, Christina Stefanitsch, Carina Strell, Lars Muhl, Lou Brundin, Linda Fredriksson, Tomas Olsson, Ulf Eriksson, Ingrid Nilsson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Abstract Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encepha
Externí odkaz:
https://doaj.org/article/18f04bdb2bef420e877bfd4a06c159be
Autor:
Antonio Uccelli, Alice Laroni, Lou Brundin, Michel Clanet, Oscar Fernandez, Seyed Massood Nabavi, Paolo A. Muraro, Roberto S. Oliveri, Ernst W. Radue, Johann Sellner, Per Soelberg Sorensen, Maria Pia Sormani, Jens Thomas Wuerfel, Mario A. Battaglia, Mark S. Freedman, on behalf of the MESEMS study group
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Multiple sclerosis (MS) is an inflammatory disease of the central nervous system with a degenerative component, leading to irreversible disability. Mesenchymal stem cells (MSC) have been shown to prevent inflammation and neurodege
Externí odkaz:
https://doaj.org/article/cecb42ab3b814fa7b6f5dace14d6516b
Autor:
Sreenivasa Raghavan Sankavaram, Ramil Hakim, Ruxandra Covacu, Arvid Frostell, Susanne Neumann, Mikael Svensson, Lou Brundin
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 950-966 (2019)
Summary: Long-term survival and integration of neural progenitor cells (NPCs) transplanted following spinal cord injury (SCI) have been observed. However, questions concerning the differentiation choice, the mechanism of action, and the contribution
Externí odkaz:
https://doaj.org/article/83daca5ac362420faeb63fda717542af
Autor:
Lara Kular, Maria Needhamsen, Milena Z. Adzemovic, Tatiana Kramarova, David Gomez-Cabrero, Ewoud Ewing, Eliane Piket, Jesper Tegnér, Stephan Beck, Fredrik Piehl, Lou Brundin, Maja Jagodic
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-20 (2019)
Abstract Background Due to limited access to brain tissue, the precise mechanisms underlying neuro-axonal dysfunction in neurological disorders such as multiple sclerosis (MS) are largely unknown. In that context, profiling DNA methylation, which is
Externí odkaz:
https://doaj.org/article/9e5fccb40def426b909ab79667969170
Autor:
Ramil Hakim, Ruxandra Covacu, Vasilios Zachariadis, Arvid Frostell, Sreenivasa Raghavan Sankavaram, Lou Brundin, Mikael Svensson
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Background Mesenchymal stem cells (MSCs) and their cellular response to various stimuli have been characterized in great detail in culture conditions. In contrast, the cellular response of MSCs in an in vivo setting is still uncharted territ
Externí odkaz:
https://doaj.org/article/d2e2f4b9628548509d0fbf7a08bceab8
Autor:
Johanna Estelius, Johan Lengqvist, Elena Ossipova, Helena Idborg, Erwan Le Maître, Magnus L. A. Andersson, Lou Brundin, Mohsen Khademi, Elisabet Svenungsson, Per-Johan Jakobsson, Jon Lampa
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background Signs of inflammation in cerebrospinal fluid (CSF) of rheumatoid arthritis patients correlate positively with fatigue, a central nervous system (CNS)-related symptom that can be partially suppressed by TNF blockade. This suggests
Externí odkaz:
https://doaj.org/article/3644b42a9d324f05bc6b3102f310d1f8