Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lotte Vanherle"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114628- (2023)
Acquired cystic fibrosis transmembrane regulator (CFTR) dysfunctions have been associated with several conditions, including myocardial infarction (MI). Here, CFTR is downregulated in brain, heart, and lung tissue and associates with inflammation and
Externí odkaz:
https://doaj.org/article/7fe8dbd075dc4dd78d3c8ce7e0c2d3a6
Autor:
Lotte Vanherle, Darcy Lidington, Franziska E. Uhl, Saskia Steiner, Stefania Vassallo, Cecilia Skoug, Joao M.N. Duarte, Sangeetha Ramu, Lena Uller, Jean-François Desjardins, Kim A. Connelly, Steffen-Sebastian Bolz, Anja Meissner
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104384- (2022)
Summary: Background: Cognitive impairment is a serious comorbidity in heart failure patients, but effective therapies are lacking. We investigated the mechanisms that alter hippocampal neurons following myocardial infarction (MI). Methods: MI was ind
Externí odkaz:
https://doaj.org/article/e8c849e59b7542508bc162f64d7699da
Autor:
Nicholas Don-Doncow, Lotte Vanherle, Frank Matthes, Sine Kragh Petersen, Hana Matuskova, Sara Rattik, Anetta Härtlova, Anja Meissner
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Evidence associates cardiovascular risk factors with unfavorable systemic and neuro-inflammation and cognitive decline in the elderly. Cardiovascular therapeutics (e.g., statins and anti-hypertensives) possess immune-modulatory functions in
Externí odkaz:
https://doaj.org/article/1745737e9e5c4f2da50b435a4a85b4c2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Heart failure (HF) affects 64 million people worldwide. Despite advancements in prevention and therapy, quality of life remains poor for many HF patients due to associated target organ damage. Pulmonary manifestations of HF are well-established. Howe
Externí odkaz:
https://doaj.org/article/132c135d02654ed594a1fc9b09aa037d
Autor:
Darcy Lidington, PhD, Jessica C. Fares, MSc, Franziska E. Uhl, PhD, Danny D. Dinh, MSc, Jeffrey T. Kroetsch, PhD, Meghan Sauvé, PhD, Firhan A. Malik, PhD, Frank Matthes, PhD, Lotte Vanherle, MSc, Arman Adel, BSc, Abdul Momen, MD, PhD, Hangjun Zhang, MD, Roozbeh Aschar-Sobbi, PhD, Warren D. Foltz, PhD, Hoyee Wan, BSc, Manabu Sumiyoshi, MD, R. Loch Macdonald, MD, PhD, Mansoor Husain, MD, Peter H. Backx, PhD, DVM, Scott P. Heximer, PhD, Anja Meissner, PhD, Steffen-Sebastian Bolz, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 940-958 (2019)
Summary: Heart failure (HF) and subarachnoid hemorrhage (SAH) chronically reduce cerebral perfusion, which negatively affects clinical outcome. This work demonstrates a strong relationship between cerebral artery cystic fibrosis transmembrane conduct
Externí odkaz:
https://doaj.org/article/aa194954f9a94652a93d9a32f78df8cb
Autor:
Anja Meissner, Alba M. Garcia-Serrano, Lotte Vanherle, Zeinab Rafiee, Nicholas Don-Doncow, Cecilia Skoug, Sara Larsson, Michael Gottschalk, Martin Magnusson, João M. N. Duarte
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 300 (2022)
Excess dietary salt reduces resting cerebral blood flow (CBF) and vascular reactivity, which can limit the fueling of neuronal metabolism. It is hitherto unknown whether metabolic derangements induced by high-salt-diet (HSD) exposure during adulthood
Externí odkaz:
https://doaj.org/article/3c46467d04984f5c8b332ff785040617
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mounting evidence indicates that the presence of cardiovascular disease (CVD) and risk factors elevates the incidence of cognitive impairment (CI) and dementia. CVD and associated decline in cardiovascular function can impair cerebral blood flow (CBF
Externí odkaz:
https://doaj.org/article/1aa290fcab9948cc98976c3ec7a762f1
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 866 (2022)
Heart failure (HF) is among the main causes of death worldwide. Alterations of sphingosine-1-phosphate (S1P) signaling have been linked to HF as well as to target organ damage that is often associated with HF. S1P’s availability is controlled by th
Externí odkaz:
https://doaj.org/article/233c3c86ddf7414cbab8121c7f313da3
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 537 (2019)
Hypertension is considered the major modifiable risk factor for the development of cognitive impairment. Because increased blood pressure is often accompanied by an activation of the immune system, the concept of neuro-inflammation gained increasing
Externí odkaz:
https://doaj.org/article/0e941796b575477d894a547aae8ddb6e
Heart failure (HF) affects 64 million people worldwide. Despite advancements in prevention and therapy, quality of life remains poor for many HF patients due to associated target organ damage. Pulmonary manifestations of HF are well-established. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0340755f57bc665eb5b6b643eb8d28
https://opus.bibliothek.uni-augsburg.de/opus4/files/97421/fimmu-13-928300.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/97421/fimmu-13-928300.pdf
