Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lotte T Spang"'
Autor:
Dorte Bjerre Steensgaard, Jesper Søndergaard Marino, Lotte T Spang, Arne Staby, Nicoline Videbæk, Christina Bartholdy, Heidrun Bosch-Traberg, Kim F. Haselmann, Désirée J Asgreen, Ole Schelde
Publikováno v:
Pharmaceutical Research. 37
Purpose Manufacturing processes for polypeptide/protein drugs are designed to ensure robust quality, efficacy and safety. Process differences introduced by follow-on manufacturers may result in changes in quality and clinical outcomes. This study inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332e5f064f78657de9161f59b5f9c913
https://doi.org/10.1007/s11095-020-02817-9
https://doi.org/10.1007/s11095-020-02817-9
Autor:
Sibel Kalyoncu, Emily K. Makowski, Lotte T Spang, Peter M. Tessier, Wenjia Lou, Samuel D Stimple, Karen Duus, Jan Amstrup, Arne Staby, Alec A. Desai, Jesper E Mogensen, Désirée J Asgreen, Yulei Zhang
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 118(2)
Biologics such as peptides and proteins possess a number of attractive attributes that make them particularly valuable as therapeutics, including their high activity, high specificity, and low toxicity. However, one of the key challenges associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d7366d41b38d260c1acfe2e3d85b5d
https://pubmed.ncbi.nlm.nih.gov/33095442
https://pubmed.ncbi.nlm.nih.gov/33095442
Autor:
Lotte T Spang, Arne Staby, Peter M. Tessier, Jesper E Mogensen, Sibel Kalyoncu, Alec A. Desai, Samuel D Stimple, Désirée J Asgreen
Publikováno v:
Biotechnology and bioengineering. 116(8)
Sensitive detection of protein aggregates is important for evaluating the quality of biopharmaceuticals and detecting misfolded proteins in several neurodegenerative diseases. However, it is challenging to detect extremely low concentrations (10 ppm)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d114d5672810c43336de50b4d8ca1269
https://pubmed.ncbi.nlm.nih.gov/30982957
https://pubmed.ncbi.nlm.nih.gov/30982957