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Autor:
Dietmar Hertsen, Sari Deketelaere, Lotte Demeurisse, Kristof Van Hecke, Veronique Van Speybroeck, Jelle De Moor, Elias Van Den Broeck, Hannelore Goossens, Lieselotte Crul, Nicola Piens, Matthias D'hooghe, Karen Mollet
Publikováno v:
CHEMISTRY-A EUROPEAN JOURNAL
The reactivity of 3-oxo-β-lactams with respect to primary amines was investigated in depth. Depending on the specific azetidin-2-one C4 substituent, this reaction was shown to selectively produce 3-imino-β-lactams (through dehydration), α-aminoami