Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Lotte C Houtepen"'
Autor:
Rosa H. Mulder, Esther Walton, Alexander Neumann, Lotte C. Houtepen, Janine F. Felix, Marian J. Bakermans-Kranenburg, Matthew Suderman, Henning Tiemeier, Marinus H. van IJzendoorn, Caroline L. Relton, Charlotte A. M. Cecil
Publikováno v:
Epigenetics, Vol 15, Iss 6-7, Pp 750-764 (2020)
Bullying among children is ubiquitous and associated with pervasive mental health problems. However, little is known about the biological pathways that change after exposure to bullying. Epigenome-wide changes in DNA methylation in peripheral blood w
Externí odkaz:
https://doaj.org/article/9f5aa2f621854067a0c4006cec04e560
Autor:
Yujie He, Lot D. de Witte, Lotte C. Houtepen, Danny M. Nispeling, Zhida Xu, Qiong Yu, Yaqin Yu, Elly M. Hol, René S. Kahn, Marco P. Boks
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-8 (2019)
Abstract Background DNA methylation has recently been identified as a mediator between in utero famine exposure and a range of metabolic and psychiatric traits. However, genome-wide analyses are scarce and cross-sectional analyses are hampered by man
Externí odkaz:
https://doaj.org/article/6b2a6789cf4a4c20881b2cb639dd7079
Autor:
Lotte C Houtepen, Jon Heron, Matthew J Suderman, Abigail Fraser, Catherine R Chittleborough, Laura D Howe
Publikováno v:
PLoS Medicine, Vol 17, Iss 3, p e1003031 (2020)
BackgroundExperiencing multiple adverse childhood experiences (ACEs) is a risk factor for many adverse outcomes. We explore associations of ACEs with educational attainment and adolescent health and the role of family and socioeconomic factors in the
Externí odkaz:
https://doaj.org/article/7a849de2b08c483abe434acd61318b4d
Autor:
Jasmine N. Khouja, Andrew J. Simpkin, Linda M. O’Keeffe, Kaitlin H. Wade, Lotte C. Houtepen, Caroline L. Relton, Matthew Suderman, Laura D. Howe
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background Gestational age at delivery is associated with health and social outcomes. Recently, cord blood DNA methylation data has been used to predict gestational age. The discrepancy between gestational age predicted from DNA methylation
Externí odkaz:
https://doaj.org/article/0e271affad7d41c79688e97f0dfa998f
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2019)
Background: Childhood adversity increases the risk of a range of mental disorders including bipolar disorder, but the underlying mechanisms are still unknown. Previous studies identified DNA methylation levels at the cg27512205 locus on the KIT Ligan
Externí odkaz:
https://doaj.org/article/d2a87632078241849fcab9a4bad1b69c
Autor:
Lotte C. Houtepen, Christiaan H. Vinkers, Tania Carrillo-Roa, Marieke Hiemstra, Pol A. van Lier, Wim Meeus, Susan Branje, Christine M. Heim, Charles B. Nemeroff, Jonathan Mill, Leonard C. Schalkwyk, Menno P. Creyghton, René S. Kahn, Marian Joëls, Elisabeth B. Binder, Marco P. M. Boks
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Exposure to childhood trauma is a major risk factor for the development of almost all psychiatric disorders. By epigenome-wide studies, here, Houtepen et al. show that DNA methylation at a locus in the Kit ligand gene (KITLG) mediates the relationshi
Externí odkaz:
https://doaj.org/article/8d086f36e6654c299d12aa96eafaf3c5
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Background: Exposure to adverse childhood experiences (ACEs) is a risk factor for poor later life health. Here, we describe the ACE variables measured in the children of the Avon Longitudinal Study of Parents and Children (ALSPAC) study, and a method
Externí odkaz:
https://doaj.org/article/bfaac1c87dca43b980f1fcf78ffb8510
Autor:
Elly M. Hol, René S. Kahn, Stella Dracheva, Nina Notman, Gijsje J. L. J. Snijders, Danny M Nispeling, Marjolein A. M. Sneeboer, Lot D. de Witte, Marco P. Boks, Yujie He, Lotte C Houtepen, Amber Berdenis van Berlekom
Publikováno v:
Epigenomics, 13, 1157-1169. Future Medicine Ltd.
Epigenomics, 13, 15, pp. 1157-1169
Epigenomics, 13, 1157-1169
Epigenomics
Epigenomics, 13, 15, pp. 1157-1169
Epigenomics, 13, 1157-1169
Epigenomics
Item does not contain fulltext Aim: Identify grey- and white-matter-specific DNA-methylation differences between schizophrenia (SCZ) patients and controls in postmortem brain cortical tissue. Materials & methods: Grey and white matter were separated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b097856840739f2fef21f3e4c6fbb739
https://doi.org/10.2217/epi-2021-0077
https://doi.org/10.2217/epi-2021-0077
Autor:
Katri Räikkönen, Marinus H. van IJzendoorn, Heather J. Zar, Nia McRae, Nour Baïz, Silvia Alemany, Andrea A. Baccarelli, Anni Malmberg, Robert O. Wright, Rosa H. Mulder, Gemma C Sharp, Darina Czamara, Charleen D. Adams, Christian M. Page, Samuli Tuominen, Marian J. Bakermans-Kranenburg, Isabella Annesi-Maesano, Maria C. Magnus, Nancy McBride, Jordi Sunyer, Caroline L Relton, Nastassja Koen, Ellen A. Nohr, Stephanie J. London, Siri E. Håberg, Elena Colicino, Marie-France Hivert, Charlotte A.M. Cecil, Eero Kajantie, Andrew Ratanatharathorn, Debbie A Lawlor, Rosalind J. Wright, John Wright, Kelly J. Brunst, Sheryl L. Rifas-Shiman, Dan J. Stein, Andrea P. Cortes Hidalgo, Jari Lahti, Thorkild I. A. Sørensen, Dawn L. DeMeo, Janine F. Felix, Paul Yousefi, Doretta Caramaschi, Jianping Jin, Martha María Téllez-Rojo, Giancarlo Pesce, Henning Tiemeier, Andres Cardenas, Lotte C Houtepen, Sara Sammallahti, Jonathan A Heiss
Publikováno v:
Molecular Psychiatry, 26(6), 1832-1845. Nature Publishing Group
Mol Psychiatry
Sammallahti, S, Cortes Hidalgo, A P, Tuominen, S, Malmberg, A, Mulder, R H, Brunst, K J, Alemany, S, McBride, N S, Yousefi, P, Heiss, J A, McRae, N, Page, C M, Jin, J, Pesce, G, Caramaschi, D, Rifas-Shiman, S L, Koen, N, Adams, C D, Magnus, M C, Baïz, N, Ratanatharathorn, A, Czamara, D, Håberg, S E, Colicino, E, Baccarelli, A A, Cardenas, A, DeMeo, D L, Lawlor, D A, Relton, C L, Felix, J F, van IJzendoorn, M H, Bakermans-Kranenburg, M J, Kajantie, E, Räikkönen, K, Sunyer, J, Sharp, G C, Houtepen, L C, Nohr, E A, Sørensen, T I A, Téllez-Rojo, M M, Wright, R O, Annesi-Maesano, I, Wright, J, Hivert, M F, Wright, R J, Zar, H J, Stein, D J, London, S J, Cecil, C A M, Tiemeier, H & Lahti, J 2021, ' Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation ', Molecular Psychiatry, vol. 26, no. 6, pp. 1832-1845 . https://doi.org/10.1038/s41380-020-00976-0
Molecular Psychiatry
Sammallahti, S, Cortes Hidalgo, A P, Tuominen, S, Malmberg, A, Mulder, R H, Brunst, K J, Alemany, S, McBride, N S, Yousefi, P, Heiss, J A, McRae, N, Page, C M, Jin, J, Pesce, G, Caramaschi, D, Rifas-Shiman, S L, Koen, N, Adams, C D, Magnus, M C, Baiz, N, Ratanatharathorn, A, Czamara, D, Haberg, S E, Colicino, E, Baccarelli, A A, Cardenas, A, DeMeo, D L, Lawlor, D A, Relton, C L, Felix, J F, van IJzendoorn, M H, Bakermans-Kranenburg, M J, Kajantie, E, Raikkonen, K, Sunyer, J, Sharp, G C, Houtepen, L C, Nohr, E A, Sørensen, T I A, Tellez-Rojo, M M, Wright, R O, Annesi-Maesano, I, Wright, J, Hivert, M-F, Wright, R J, Zar, H J, Stein, D J, London, S J, Cecil, C A M, Tiemeier, H & Lahti, J 2021, ' Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation ', Molecular Psychiatry, vol. 26, pp. 1832–1845 . https://doi.org/10.1038/s41380-020-00976-0
et al. 2021, ' Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation ', Molecular Psychiatry, vol. 26, no. 6, pp. 1832-1845 . https://doi.org/10.1038/s41380-020-00976-0
Mol Psychiatry
Sammallahti, S, Cortes Hidalgo, A P, Tuominen, S, Malmberg, A, Mulder, R H, Brunst, K J, Alemany, S, McBride, N S, Yousefi, P, Heiss, J A, McRae, N, Page, C M, Jin, J, Pesce, G, Caramaschi, D, Rifas-Shiman, S L, Koen, N, Adams, C D, Magnus, M C, Baïz, N, Ratanatharathorn, A, Czamara, D, Håberg, S E, Colicino, E, Baccarelli, A A, Cardenas, A, DeMeo, D L, Lawlor, D A, Relton, C L, Felix, J F, van IJzendoorn, M H, Bakermans-Kranenburg, M J, Kajantie, E, Räikkönen, K, Sunyer, J, Sharp, G C, Houtepen, L C, Nohr, E A, Sørensen, T I A, Téllez-Rojo, M M, Wright, R O, Annesi-Maesano, I, Wright, J, Hivert, M F, Wright, R J, Zar, H J, Stein, D J, London, S J, Cecil, C A M, Tiemeier, H & Lahti, J 2021, ' Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation ', Molecular Psychiatry, vol. 26, no. 6, pp. 1832-1845 . https://doi.org/10.1038/s41380-020-00976-0
Molecular Psychiatry
Sammallahti, S, Cortes Hidalgo, A P, Tuominen, S, Malmberg, A, Mulder, R H, Brunst, K J, Alemany, S, McBride, N S, Yousefi, P, Heiss, J A, McRae, N, Page, C M, Jin, J, Pesce, G, Caramaschi, D, Rifas-Shiman, S L, Koen, N, Adams, C D, Magnus, M C, Baiz, N, Ratanatharathorn, A, Czamara, D, Haberg, S E, Colicino, E, Baccarelli, A A, Cardenas, A, DeMeo, D L, Lawlor, D A, Relton, C L, Felix, J F, van IJzendoorn, M H, Bakermans-Kranenburg, M J, Kajantie, E, Raikkonen, K, Sunyer, J, Sharp, G C, Houtepen, L C, Nohr, E A, Sørensen, T I A, Tellez-Rojo, M M, Wright, R O, Annesi-Maesano, I, Wright, J, Hivert, M-F, Wright, R J, Zar, H J, Stein, D J, London, S J, Cecil, C A M, Tiemeier, H & Lahti, J 2021, ' Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation ', Molecular Psychiatry, vol. 26, pp. 1832–1845 . https://doi.org/10.1038/s41380-020-00976-0
et al. 2021, ' Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation ', Molecular Psychiatry, vol. 26, no. 6, pp. 1832-1845 . https://doi.org/10.1038/s41380-020-00976-0
Maternal anxiety during pregnancy is associated with adverse foetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered foetal DNA methylation (DNAm) has been proposed as a potential underlying mechanism. In the current s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501c836633282e2faeaa37262dbe74f8
https://pure.eur.nl/en/publications/851995bd-fafb-4475-adcb-3f64e7e98126
https://pure.eur.nl/en/publications/851995bd-fafb-4475-adcb-3f64e7e98126
Autor:
Marinus H. van IJzendoorn, Rosa H. Mulder, Caroline L Relton, Alexander Neumann, Lotte C Houtepen, Andrew J Simpkin, Esther Walton, Bastiaan T. Heijmans, Henning Tiemeier, Marian J. Bakermans-Kranenburg, Matthew Suderman, Janine F. Felix, Jolien Rijlaarsdam, Vincent W. V. Jaddoe, Tom R. Gaunt, Charlotte A.M. Cecil
Publikováno v:
Human Molecular Genetics, 30(1), 119-134. Oxford University Press
Human Molecular Genetics, 30(1), 119-134. OXFORD UNIV PRESS
Mulder, R H, Neumann, A, Cecil, C A M, Walton, E, Houtepen, L C, Simpkin, A J, Rijlaarsdam, J, Heijmans, B T, Gaunt, T R, Felix, J F, Jaddoe, V W V, Bakermans-Kranenburg, M J, Tiemeier, H, Relton, C L, van IJzendoorn, M H & Suderman, M 2021, ' Epigenome-wide change and variation in DNA methylation in childhood : trajectories from birth to late adolescence ', Human molecular genetics, vol. 30, no. 1, pp. 119-134 . https://doi.org/10.1093/hmg/ddaa280
Human Molecular Genetics
Mulder, R H, Neumann, A, Cecil, C A M, Walton, E, Houtepen, L C, Simpkin, A J, Rijlaarsdam, J, Heijmans, B T, Gaunt, T R, Felix, J F, Jaddoe, V W V, Bakermans-Kranenburg, M J, Tiemeier, H, Relton, C L, van IJzendoorn, M H & Suderman, M 2021, ' Epigenome-wide change and variation in DNA methylation in childhood : Trajectories from birth to late adolescence ', Human Molecular Genetics, vol. 30, no. 1, ddaa280, pp. 119-134 . https://doi.org/10.1093/hmg/ddaa280
Human molecular genetics, 30(1), 119-134. Oxford University Press
Mulder, R H, Gaunt, T R, Relton, C L, Suderman, M & al., E 2021, ' Epigenome-wide change and variation in DNA methylation in childhood : trajectories from birth to late adolescence ', Genome Biology, vol. 30, no. 1, ddaa280, pp. 119-134 . https://doi.org/10.1093/hmg/ddaa280
Human Molecular Genetics, 30(1), 119-134. OXFORD UNIV PRESS
Mulder, R H, Neumann, A, Cecil, C A M, Walton, E, Houtepen, L C, Simpkin, A J, Rijlaarsdam, J, Heijmans, B T, Gaunt, T R, Felix, J F, Jaddoe, V W V, Bakermans-Kranenburg, M J, Tiemeier, H, Relton, C L, van IJzendoorn, M H & Suderman, M 2021, ' Epigenome-wide change and variation in DNA methylation in childhood : trajectories from birth to late adolescence ', Human molecular genetics, vol. 30, no. 1, pp. 119-134 . https://doi.org/10.1093/hmg/ddaa280
Human Molecular Genetics
Mulder, R H, Neumann, A, Cecil, C A M, Walton, E, Houtepen, L C, Simpkin, A J, Rijlaarsdam, J, Heijmans, B T, Gaunt, T R, Felix, J F, Jaddoe, V W V, Bakermans-Kranenburg, M J, Tiemeier, H, Relton, C L, van IJzendoorn, M H & Suderman, M 2021, ' Epigenome-wide change and variation in DNA methylation in childhood : Trajectories from birth to late adolescence ', Human Molecular Genetics, vol. 30, no. 1, ddaa280, pp. 119-134 . https://doi.org/10.1093/hmg/ddaa280
Human molecular genetics, 30(1), 119-134. Oxford University Press
Mulder, R H, Gaunt, T R, Relton, C L, Suderman, M & al., E 2021, ' Epigenome-wide change and variation in DNA methylation in childhood : trajectories from birth to late adolescence ', Genome Biology, vol. 30, no. 1, ddaa280, pp. 119-134 . https://doi.org/10.1093/hmg/ddaa280
DNA methylation (DNAm) is known to play a pivotal role in childhood health and development, but a comprehensive characterization of genome-wide DNAm trajectories across this age period is currently lacking. We have therefore performed a series of epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea2e1d0ce47972879a19e3bc6618f44
https://pure.eur.nl/en/publications/faebaf1d-3e77-4db3-86f4-b9387842167e
https://pure.eur.nl/en/publications/faebaf1d-3e77-4db3-86f4-b9387842167e