Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lotta Borgius"'
Autor:
Jan Mulder, Tibor Harkany, Katarzyna Malenczyk, Tomas Hökfelt, Fatima Girach, Mathias Uhlén, Masahiko Watanabe, Lotta Borgius, Ming-Dong Zhang, Valentina Cinquina, Csaba Adori, Changgeng Peng, Peter Löw, Patrik Ernfors, Ole Kiehn, Jie Su, Nicholas Mitsios
Publikováno v:
Journal of Clinical Investigation
Pain signals are transmitted by multisynaptic glutamatergic pathways. Their first synapse between primary nociceptors and excitatory spinal interneurons gates the sensory load. In this pathway, glutamate release is orchestrated by Ca2+-sensor protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215be8df6a9fa497bc110f3674c0ec09
https://europepmc.org/articles/PMC6118643/
https://europepmc.org/articles/PMC6118643/
Autor:
Hannah Hochgerner, Amit Zeisel, Jon E. T. Jakobsson, Puneet Rinwa, Lotta Borgius, Gioele La Manno, Sten Linnarsson, Martin Häring, Nilesh Sharma, Malin C. Lagerström, Patrik Ernfors, Peter Lönnerberg, Ole Kiehn
Publikováno v:
Nature Neuroscience
The dorsal horn of the spinal cord is critical to processing distinct modalities of noxious and innocuous sensation, but little is known of the neuronal subtypes involved, hampering efforts to deduce principles governing somatic sensation. Here we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5ab10bafadbd7c0c401526363a6f84
https://pubmed.ncbi.nlm.nih.gov/29686262
https://pubmed.ncbi.nlm.nih.gov/29686262
Autor:
Peter Löw, Ole Kiehn, Hiroshi Nishimaru, Yuka Kunugise, Ramon Reig, Lotta Borgius, Shigeyoshi Itohara, Takuji Iwasato, Vanessa Caldeira
Publikováno v:
The Journal of Neuroscience. 34:3841-3853
EphA4 signaling is essential for the spatiotemporal organization of neuronal circuit formation. In mice, deletion of this signaling pathway causes aberrant midline crossing of axons from both brain and spinal neurons and the complete knock-outs (KOs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3268a6a8207d8639746cf27e0796dc5
https://doi.org/10.1523/jneurosci.4992-13.2014
https://doi.org/10.1523/jneurosci.4992-13.2014
Autor:
Takuji Iwasato, Lotta Borgius, Kimberly J. Dougherty, Martin Hägglund, Ole Kiehn, Shigeyoshi Itohara
Publikováno v:
Proceedings of the National Academy of Sciences. 110:11589-11594
Neural networks in the spinal cord known as central pattern generators produce the sequential activation of muscles needed for locomotion. The overall locomotor network architectures in limbed vertebrates have been much debated, and no consensus exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77f9873ceb29b1521a4818bd1532a74
https://doi.org/10.1073/pnas.1304365110
https://doi.org/10.1073/pnas.1304365110
Publikováno v:
Scientific Reports
Rhythm generating neurons are thought to be ipsilaterally-projecting excitatory neurons in the thoracolumbar mammalian spinal cord. Recently, a subset of Shox2 interneurons (Shox2 non-V2a INs) was found to fulfill these criteria and make up a fractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3625c3da1ad5f6570d453c43a5eedb6e
https://pubmed.ncbi.nlm.nih.gov/28128321
https://pubmed.ncbi.nlm.nih.gov/28128321
Autor:
Davit Sargsyan, Gayane Margaryan, Ole Kiehn, Lotta Borgius, Line Lundfald, Carlos Ernesto Restrepo
Publikováno v:
European Journal of Neuroscience. 34:1102-1112
Neuronal networks in the spinal cord termed central pattern generators (CPGs) are responsible for the generation of rhythmic movements, such as walking. The axon guidance molecule EphA4 has been suggested to play a role in the configuration of spinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5682ca74377b1932750a4047936b1ddd
https://doi.org/10.1111/j.1460-9568.2011.07838.x
https://doi.org/10.1111/j.1460-9568.2011.07838.x
Autor:
Ole Kiehn, Kimberly J. Dougherty, Martin Hägglund, Carlos Ernesto Restrepo, Adolfo E. Talpalar, Lotta Borgius
Publikováno v:
Biochemical and Biophysical Research Communications. 396:11-18
Locomotion in mammals is a complex motor act that involves the activation of a large number of muscles in a well-coordinated pattern. Understanding the network organization of the intrinsic spinal networks that control the locomotion, the central pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4397fdd90ebdddd9fde6bdb982585ed2
https://doi.org/10.1016/j.bbrc.2010.02.107
https://doi.org/10.1016/j.bbrc.2010.02.107
Publikováno v:
Nature Neuroscience. 13:246-252
Central pattern generators (CPGs) are spinal neuronal networks required for locomotion. Glutamatergic neurons have been implicated as being important for intrinsic rhythm generation in the CPG and for the command signal for initiating locomotion, alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0953812c7149c3e4a5c8cc82cc7b3c
https://doi.org/10.1038/nn.2482
https://doi.org/10.1038/nn.2482
Autor:
Lotta Borgius, Katharina A. Quinlan, Carlos Ernesto Restrepo, Toshiaki Endo, Ole Kiehn, Line Lundfald, Adolfo E. Talpalar
Publikováno v:
Brain Research Reviews. 57:56-63
Locomotion in mammals is to a large degree controlled directly by intrinsic spinal networks, called central pattern generators (CPGs). The overall function of these networks is governed by interaction between inhibitory and excitatory neurons. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242d076d468fd77b137eb42992d26e1c
https://doi.org/10.1016/j.brainresrev.2007.07.002
https://doi.org/10.1016/j.brainresrev.2007.07.002
Publikováno v:
Journal of Neurochemistry. 97:1403-1411
The orphan nuclear receptor Nurr1 is expressed in the developing and adult central nervous system. Previous studies have shown that Nurr1 is essential for the generation of midbrain dopamine neurons. Furthermore, Nurr1 is critical for respiratory fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbdb991fc94381b21ae97bda466bec4
https://doi.org/10.1111/j.1471-4159.2006.03829.x
https://doi.org/10.1111/j.1471-4159.2006.03829.x