An investigation of excipients for a stable Orf viral vector formulation.

Autor: Eilts F; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, Giessen 35390, Germany., Harsy YMJ; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, Giessen 35390, Germany., Lothert K; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, Giessen 35390, Germany., Pagallies F; Department of Immunology, University of Tuebingen, Auf der Morgenstelle 15, Tuebingen 72076, Germany., Amann R; Department of Immunology, University of Tuebingen, Auf der Morgenstelle 15, Tuebingen 72076, Germany; PRiME Vector Technologies, Herrenberger Straße 24, Tuebingen 72070, Germany., Wolff MW; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, Giessen 35390, Germany. Electronic address: michael.wolff@lse.thm.de.

Publikováno v: Virus research [Virus Res] 2023 Oct 15; Vol. 336, pp. 199213. Date of Electronic Publication: 2023 Sep 06.

Evaluation of restricted access media for the purification of cell culture-derived Orf viruses.

Autor: Lothert K; Institute of Bioprocess Engineering and Pharmaceutical Technology University of Applied Sciences Mittelhessen (THM) Giessen Germany., Harsy YMJ; Institute of Bioprocess Engineering and Pharmaceutical Technology University of Applied Sciences Mittelhessen (THM) Giessen Germany., Endres P; Tosoh Bioscience GmbH, Separations Business Unit - Europe Griesheim Germany., Müller E; Tosoh Bioscience GmbH, Separations Business Unit - Europe Griesheim Germany., Wolff MW; Institute of Bioprocess Engineering and Pharmaceutical Technology University of Applied Sciences Mittelhessen (THM) Giessen Germany.

Publikováno v: Engineering in life sciences [Eng Life Sci] 2023 Jul 14; Vol. 23 (9), pp. e2300009. Date of Electronic Publication: 2023 Jul 14 (Print Publication: 2023).

Membrane-based steric exclusion chromatography for the purification of a recombinant baculovirus and its application for cell therapy

Autor: Lothert, K., Sprick, G., Beyer, F., Lauria, G., Czermak, P., Wolff, M.W.

The continuously increasing potential of stem cell treatments for various medical conditions has accelerated the need for fast and efficient purification techniques for individualized cell therapy applications. Genetic stem cell engineering is common

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::8012cdb1b49a0eee6cb147a90f7f5c5c
https://publica.fraunhofer.de/handle/publica/262579

A Summary of Practical Considerations for the Application of the Steric Exclusion Chromatography for the Purification of the Orf Viral Vector.

Autor: Eilts F; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, 35390 Giessen, Germany., Lothert K; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, 35390 Giessen, Germany., Orbay S; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, 35390 Giessen, Germany., Pagallies F; Department of Immunology, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany., Amann R; Department of Immunology, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany.; PRiME Vector Technologies, Herrenberger Straße 24, 72070 Tuebingen, Germany., Wolff MW; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Wiesenstr.14, 35390 Giessen, Germany.; Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Ohlebergsweg 12, 35392 Giessen, Germany.

Publikováno v: Membranes [Membranes (Basel)] 2022 Oct 29; Vol. 12 (11). Date of Electronic Publication: 2022 Oct 29.

Quantification methods for viruses and virus-like particles applied in biopharmaceutical production processes.

Autor: Lothert K; Department of Life Science Engineering, Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Giessen, Germany., Eilts F; Department of Life Science Engineering, Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Giessen, Germany., Wolff MW; Department of Life Science Engineering, Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Giessen, Germany.; Branch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Giessen, Germany.

Publikováno v: Expert review of vaccines [Expert Rev Vaccines] 2022 Aug; Vol. 21 (8), pp. 1029-1044. Date of Electronic Publication: 2022 May 06.