Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lothar Uher"'
Autor:
Tamara R. McBrayer, Biing Y. Lin, Kiran Verma, Ozkan Sari, Olivia Ollinger Russell, Judy Pattassery, Yong Jiang, Maria Luz G. Pascual, Steven J. Coats, Seema Mengshetti, Leda Bassit, Jong Hyun Cho, Reuben Ovadia, Sijia Tao, Sam Lee, Mahesh Kasthuri, Robert A. Domaoal, Tony Whitaker, Coralie De Schutter, Raymond F. Schinazi, Longhu Zhou, Lothar Uher, Hongwang Zhang, Maryam Ehteshami, Franck Amblard
Publikováno v:
J Med Chem
Hepatitis C virus (HCV) nucleoside inhibitors display pan-genotypic activity, a high barrier to the selection of resistant virus, and are some of the most potent direct-acting agents with durable sustained virologic response in humans. Herein, we rep
Publikováno v:
Gene. 234:109-117
A gene encoding a novel human 3′, 5′-cyclic nucleotide phosphodiesterase (PDE) was identified and characterized. PDE10A1 encodes a protein that is 779 amino acids in length. An incomplete cDNA for a second 5′-splice variant, PDE10A2, was isolat
Autor:
Ryan Hambleton, Lothar Uher, Judith Krall, Kim N. McCaw, Matthew A. Movsesian, Vincent A. Florio, Przemysław B. Radwański, Sharon L. Wolda, Fabrice Vandeput
Publikováno v:
The Journal of biological chemistry. 282(45)
Isoforms in the PDE1 family of cyclic nucleotide phosphodiesterases were recently found to comprise a significant portion of the cGMP-inhibited cAMP hydrolytic activity in human hearts. We examined the expression of PDE1 isoforms in human myocardium,
Autor:
Bryan A. Jones, Linda M. McAllister-Lucas, Kate Loughney, Guy J Rosman, Ken Ferguson, Howard Monique L, William K. Sonnenburg, Lothar Uher, Sharron H. Francis, Teresa R Hill, Vincent A. Florio, Sharon L. Wolda, Joseph A. Beavo, Jackie D. Corbin
Publikováno v:
Gene. 216(1)
Human cGMP-binding, cGMP-specific 3′,5′-cyclic nucleotide phosphodiesterase (PDE5A) cDNAs were isolated. A 3.1-kb composite DNA sequence assembled from overlapping cDNAs encodes an 875-amino-acid protein with a predicted molecular mass of 100 012
Publikováno v:
Nucleic Acids Research. 15:6075-6090
A type II restriction endonuclease, named CviJI, was isolated from a eukaryotic Chlorella-like green alga infected with the dsDNA containing virus IL-3A. CviJI is the first restriction endonuclease to recognize the sequence PuGCPy; CviJI cleaves DNA