Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Lothar Spies"'
Autor:
Roland Opfer, Julia Krüger, Lothar Spies, Marco Hamann, Carla A. Wicki, Hagen H. Kitzler, Carola Gocke, Diego Silva, Sven Schippling
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102478- (2020)
Introduction: Several recent studies indicate that deep gray matter or thalamic volume loss (VL) might be promising surrogate markers of disease activity in multiple sclerosis (MS) patients. To allow applying these markers to individual MS patients i
Externí odkaz:
https://doaj.org/article/ab0485c77cc442048f2b2f5ac9d2a53e
Autor:
Christine Egger, Roland Opfer, Chenyu Wang, Timo Kepp, Maria Pia Sormani, Lothar Spies, Michael Barnett, Sven Schippling
Publikováno v:
NeuroImage: Clinical, Vol 13, Iss C, Pp 264-270 (2017)
Introduction: Magnetic resonance imaging (MRI) has become key in the diagnosis and disease monitoring of patients with multiple sclerosis (MS). Both, T2 lesion load and Gadolinium (Gd) enhancing T1 lesions represent important endpoints in MS clinical
Externí odkaz:
https://doaj.org/article/db735fdc58c140678dd81fb1dbf656e7
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Purpose: Thalamic atrophy and whole brain atrophy in multiple sclerosis (MS) are associated with disease progression. The motivation of this study was to propose and evaluate a new grouping scheme which is based on MS patients' whole brain and thalam
Externí odkaz:
https://doaj.org/article/f120a71c95f041d9b84e4da9fd25c6a5
Autor:
Roland Opfer, Julia Krüger, Lothar Spies, Ann-Christin Ostwaldt, Hagen H. Kitzler, Sven Schippling, Ralph Buchert
Publikováno v:
European Radiology, 33 (3)
Objectives To develop an automatic method for accurate and robust thalamus segmentation in T1w-MRI for widespread clinical use without the need for strict harmonization of acquisition protocols and/or scanner-specific normal databases. Methods A thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7303df6867a90d535b2c099e662a76e
https://hdl.handle.net/20.500.11850/578385
https://hdl.handle.net/20.500.11850/578385
Publikováno v:
Neuroradiology, 64 (10)
Purpose Total intracranial volume (TIV) is often a nuisance covariate in MRI-based brain volumetry. This study compared two TIV adjustment methods with respect to their impact on z-scores in single subject analyses of regional brain volume estimates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c09b985e67aa89cc245d32d2891fbc
Autor:
Roland Opfer, Alexander Schlaefer, Ann-Christin Ostwaldt, Hagen H. Kitzler, Sven Schippling, Lothar Spies, Julia Krüger, Benjamin Geisler
Automated quantification of infratentorial multiple sclerosis lesions on magnetic resonance imaging is clinically relevant but challenging. To overcome some of these problems, we propose a fully automated lesion segmentation algorithm using 3D convol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e672b079242d2cb6e2788c1d02d0f77
https://publica.fraunhofer.de/handle/publica/415441
https://publica.fraunhofer.de/handle/publica/415441
Autor:
Carsten Lukas, Jan Klein, Sven Kuckertz, Florian Weiler, Britta Matusche, Lothar Spies, Stefan Heldmann
Publikováno v:
Medical Imaging 2021: Computer-Aided Diagnosis.
Inflammatory white matter brain lesions are a key pathological finding in patients suffering from multiple sclerosis (MS). Image based quantification of different characteristics of these lesions has become an elemental bio-marker in both diagnosis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e707ac4132d7c38023733abf07c289f
https://doi.org/10.1117/12.2582156
https://doi.org/10.1117/12.2582156
Autor:
Anja Mäurer, Per Suppa, Ralph Buchert, Ivayla Apostolova, Elisabeth Steinhagen-Thiessen, Till Nierhaus, Alzheimer’s Disease Neuroimaging Initiative, Lothar Spies, Jochen B. Fiebach, Catharina Lange, Michel J. Grothe
Publikováno v:
Neurobiology of aging 65, 41-50 (2018). doi:10.1016/j.neurobiolaging.2018.01.002
Structural deterioration and volume loss of the hippocampal formation is observed in many diseases associated with memory decline. Paradoxically, glucose metabolism of the hippocampal formation can be increased at the same time. This might be a conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d2bf4c48ad451080ae222bb543c60d
https://doi.org/10.1016/j.neurobiolaging.2018.01.002
https://doi.org/10.1016/j.neurobiolaging.2018.01.002
Autor:
Ralph Buchert, Samantha Galluzzi, Alzheimer’s Disease Neuroimaging Initiative, Per Suppa, Harald Hampel, Roland Opfer, Simone Lista, Adam J. Schwarz, Lothar Spies, Enrica Cavedo, Catharina Lange
Publikováno v:
Journal of Alzheimer's Disease. 60:151-164
BACKGROUND MRI-based hippocampus volume is a core clinical biomarker for identification of Alzheimer's disease (AD). OBJECTIVE To assess robustness of automatic hippocampus volumetry with the freely available FSL-FIRST software with respect to short-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7807fc52ef3570f62998e81297a9d644
https://doi.org/10.3233/jad-161108
https://doi.org/10.3233/jad-161108
Autor:
Marius Grad, Jan Zentgraf, Ulrich Schultheiss, Lukas Esper, Andreas Diemar, Ulf Noster, Lothar Spiess
Publikováno v:
Metals, Vol 14, Iss 9, p 959 (2024)
During the hot pressing of pure titanium and different carbon steels in a temperature range of ϑ = 950–1050 °C, a compound layer up to dL≈10 μm thick is formed at the titanium–steel interface. With a higher carbon content of the used steel,
Externí odkaz:
https://doaj.org/article/ccc86cd9ad4a4ea68eae2af0f51569ff