Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Lothar Bernd Zimmerhackl"'
Autor:
Magdalena Riedl, Verena Jeller, Reinhard Würzner, Lambert P. van den Heuvel, Günter Weiss, Alejandra Rosales, Tanja Maier, Karsten Häffner, Thomas Giner, Therese Jungraithmayr, Johannes Hofer, Ulrike Walden, Dorothea Heininger, Lothar Bernd Zimmerhackl, Giacomo D. Simonetti
Publikováno v:
Journal of Immunological Methods, 435, 60-67
Journal of Immunological Methods, 435, pp. 60-67
Journal of Immunological Methods, 435, pp. 60-67
Atypical hemolytic uremic syndrome (aHUS) is a devastating disease characterized by thrombus formation in the microvasculature and is associated with complement dysregulation. The recommended treatment is eculizumab, an humanized monoclonal antibody,
Publikováno v:
Journal of Pediatric Infectious Diseases. :111-114
Despite advances in the management of severe sepsis, the mortality rate of septic shock in children and adults remains high. Meningococcal disease is the leading cause of sepsis affecting previously healthy children and young adults. In a septic infe
Autor:
Alejandra, Rosales, Johannes, Hofer, Lothar-Bernd, Zimmerhackl, Therese C, Jungraithmayr, Magdalena, Riedl, Thomas, Giner, Alexander, Strasak, Dorothea, Orth-Höller, Reinhard, Würzner, Helge, Karch, R, Würzner
Publikováno v:
Clinical Infectious Diseases. 54:1413-1421
BACKGROUND The aim of this study was to evaluate the long-term prognosis of children with hemolytic uremic syndrome (HUS). METHODS Over a 6-year period, 619 pediatric patients with the clinical diagnosis of HUS were registered in Austria and Germany,
Autor:
Lothar Bernd Zimmerhackl, Therese Jungraithmayr, Matthias Frosch, Martina Prelog, Johannes Elias, Ulrich Vogel, Johannes Hofer, Manuela Zlamy
Publikováno v:
Pediatric Transplantation. 16:E246-E250
We report successful kidney transplantation in a 10-yr-old boy with aHUS and heterozygous factor H mutation using the terminal complement inhibitor eculizumab to avoid recurrence of aHUS in the renal graft. Vaccination against meningococcus C (Men C)
Autor:
Lutz T. Weber, Eileen Tsai, Dirk Kuypers, Burkhard Tönshoff, Lothar Bernd Zimmerhackl, Elias David-Neto, Jens Goebel, Alexander A. Vinks, Guido Filler, Robert B. Ettenger, Teun van Gelder
Publikováno v:
Transplantation Reviews, 25(2), 78-89. W.B. Saunders
Mycophenolate mofetil (MMF) is widely used for maintenance immunosuppressive therapy in pediatric renal and heart transplant recipients. Children undergo developmental changes (ontogeny) of drug disposition, which may affect drug metabolism of the ac
Publikováno v:
Klinische Pädiatrie. 222:302-307
BACKGROUND: Lyme neuroborreliosis (LNB) is the second most common manifestation of Borrelia burgdorferi sensu lato (s. l.) infection in Europe. LNB is difficult to differentiate from other aetiologies of aseptic meningitis. Diagnostic criteria for LN
Autor:
Gerda Falkensammer, Andrea Griesmacher, Gerhard Luef, Markus Rauchenzauner, Wolfgang Högler, Lothar-Bernd Zimmerhackl, Edda Haberlandt, Tobias Tatarczyk, Alexander Strasak
Publikováno v:
Developmental Medicine & Child Neurology. 52:283-288
Aim The aim of this study was to determine the influence of chronic monotherapy with antiepileptic drugs (AEDs) on vitamin D levels, bone metabolism, and body composition. Method Eighty-five children (38 males, 47 females; mean age 12y 5mo, SD 3y 4mo
Publikováno v:
Pediatric Transplantation. 14:41-47
Reports about efficacy and safety of live-virus attenuated vaccines in patients before and after transplantation are mainly based on small patient numbers, making general recommendations for this patient population difficult. Children and adults as w
Autor:
Elisabeth Steichen, Deborah J G Mackay, Barbara Wiedemann, Julia Koehle, Dagmar Meraner, Lothar-Bernd Zimmerhackl, Sarah E. Flanagan, Sian Ellard, Edith Schober, Andrew T. Hattersley, Thomas Waldhoer, Sabine E. Hofer
Publikováno v:
Pediatric Diabetes. 11:18-23
Background: Neonatal diabetes mellitus (NDM) is a rare monogenic form of diabetes which is diagnosed in the first 6 months of life. Several studies in the last few years provide information on genetic causes for NDM. Objective: The aim of this study
Autor:
Lothar Bernd Zimmerhackl, Verena Fally, Karl Lhotta, Véronique Frémeaux-Bacchi, Reinhard Würzner, Johanna Scheiring, Gert Mayer, Thomas Giner, Andreas R. Janecke, Barbara Petzlberger
Publikováno v:
Clinical Journal of the American Society of Nephrology. 4:1356-1362
Background and objectives: Atypical hemolytic uremic syndrome (aHUS) is associated with mutations in genes encoding complement-regulatory proteins factor H, I and B and membrane cofactor protein. Recently, heterozygous gain-of-function mutations in t