Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lorri L Burris"'
Autor:
Thomas P. Burris, Bruce D. Pascal, Ruben D. Garcia-Ordonez, Jeffrey Alan Dodge, Monica A. Istrate, Michael J. Chalmers, Scott A. Busby, Yongjun Wang, Keith R. Stayrook, Patrick R. Griffin, Jun Zhang, Lorri L Burris, John B. Bruning, Douglas J. Kojetin
Publikováno v:
Nature structural & molecular biology
The vitamin D receptor (VDR) functions as an obligate heterodimer in complex with the retinoid X receptor (RXR). These nuclear receptors are multidomain proteins, and it is unclear how various domains interact with one another within the nuclear rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760a2a0ab05cf6084e88a0f79db27f1b
http://europepmc.org/articles/PMC3087838
http://europepmc.org/articles/PMC3087838
Autor:
Yanfei L. Ma, Lorri L Burris, Henry Uhlman Bryant, Qing Qiang Zeng, Chahrzad Montrose-Rafizadeh, Jianliang Lu, Keith R. Stayrook, Stephen J. Iturria, Masahiko Sato, Allen Schmidt, Robert J. Barr
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 25(6)
Vitamin D(3) analogues were shown to be beneficial for osteoporosis and other indications, but their narrow therapeutic window between efficacy and hypercalcemia has limited their clinical utility. A nonsecosteroidal, tissue-selective, orally bioavai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ea9a6a84c318d080080815690aa481
https://pubmed.ncbi.nlm.nih.gov/20200930
https://pubmed.ncbi.nlm.nih.gov/20200930
Autor:
Thomas P. Burris, Lorri L Burris, Keith R. Stayrook, Amanda K Nosie, Srilatha Raghuram, Fraydoon Rastinejad, Don B McClure, Sepideh Khorasanizadeh, Pengxiang Huang, Pamela M. Rogers
The nuclear receptors REV-ERBalpha (encoded by NR1D1) and REV-ERBbeta (NR1D2) have remained orphans owing to the lack of identified physiological ligands. Here we show that heme is a physiological ligand of both receptors. Heme associates with the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dca48dc362f1538863929f42fb69fd
https://lirias.kuleuven.be/handle/123456789/592878
https://lirias.kuleuven.be/handle/123456789/592878
Autor:
Thomas P. Burris, Keith A. Houck, Christopher D. Hepler, Benjamin C. Yaden, Kelli S. Bramlett, Heather A Bullock, Venkatesh Krishnan, Robert J. Barr, Keith R. Stayrook, Rachelle J. Sells Galvin, Richard W. Zink, Chahrzad Montrose, Lorri L Burris, Christine C. Cheng, Wayne P. Bocchinfuso, Harold E. Osborne
Publikováno v:
Molecular pharmacology. 67(3)
Guggulsterone (GS) is the active substance in guggulipid, an extract of the guggul tree, Commiphora mukul, used to treat a variety of disorders in humans, including dyslipidemia, obesity, and inflammation. The activity of GS has been suggested to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86aa58e5a1cb3b2f8e40e96d27d8425b
https://pubmed.ncbi.nlm.nih.gov/15602004
https://pubmed.ncbi.nlm.nih.gov/15602004
Autor:
Ruben D. Garcia-Ordonez, Thomas P. Burris, Michael J. Chalmers, Jeffery A. Dodge, Jun Zhang, Patrick R. Griffin, Keith R. Stayrook, Bruce D. Pascal, Lorri L Burris
Publikováno v:
Structure. (10):1332-1341
SummaryRegulation of nuclear receptor (NR) activity is driven by alterations in the conformational dynamics of the receptor upon ligand binding. Previously, we demonstrated that hydrogen/deuterium exchange (HDX) can be applied to determine novel mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae85c681206b8042c9deaa71eca83ab
Autor:
Yang N; Endocrine Research, Lilly Research Laboratories, Division of Eli Lilly & Co., Lilly Corporate Center, Indianapolis, IN 46285, USA., Kays JS, Skillman TR, Burris L, Seng TW, Hammond C
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2005 Jan; Vol. 312 (1), pp. 127-33. Date of Electronic Publication: 2004 Sep 08.