Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lorrene Buckley Kedderis"'
Autor:
Robert L. Hall, Haig P. Bozigian, Lorrene Buckley Kedderis, Steadman D. Harrison, Robert L. Susick, James M. Kleeman, Thomas E. Palmer
Publikováno v:
Fundamental and Applied Toxicology. 25:201-217
Toxicity of the Protein Kinase C Inhibitor Safingol Administered Alone and in Combination with Chemotherapeutic Agents. Kedderis, L. B., Bozigian, H. P., Kleeman, J. M., Hall, R. L., Palmer, T. E., Harrison, S. D., Jr., and Susick, R. L., Jr. (1995).
Autor:
Linda S. Birnbaum, Janet J. Diliberto, James Grainger, J.A. Jackson, Donald G. Patterson, Lorrene Buckley Kedderis
Publikováno v:
Journal of Toxicology and Environmental Health. 41:53-69
Polybrominated dibenzo-p-dioxins and dibenzofurans have been identified as potential environmental contaminants. The present studies were designed to characterize the chemical disposition of a tetrabrominated dibenzofuran. The isomer-specific pattern
Publikováno v:
Fundamental and Applied Toxicology. 21:405-411
Effect of Dose, Time, and Pretreatment on the Biliary Excretion and Tissue Distribution of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in the Rat. Kedderis, L. B., Andersen, M. E., and Birnbaum, L. S. (1993). Fundam. Appl. Toxicol. 21, 405-411. Previous stud
Publikováno v:
Fundamental and Applied Toxicology. 21:425-432
The Effect of Pretreatment on the Biliary Excretion of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 3,3′,4,4′-Tetrachlorobiphenyl in the rat. McKinley, M. K., Kedderis, L. B., and Birnbaum, L. S. (1993). Fundam. Appl.
Autor:
Jeremy Mills, Linda S. Birnbaum, William F. Greenlee, Melvin E. Andersen, Lorrene Buckley Kedderis, Diether Neubert, Michael L. Gargas
Publikováno v:
Risk Analysis. 13:25-36
Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD), a widespread polychlorinated aromatic hydrocarbon, caused tumors in the liver and other sites when administered chronically to rats at doses as low as 0.01 microgram/kg/day. It functions in combinat
Publikováno v:
Toxicology and applied pharmacology. 121(1)
Biologically based models serve as valuable tools for integration of mechanistic pharmacokinetic data by their explicit definition of important determinants of chemical disposition. The objective of the present work was to develop a physiologically b
Publikováno v:
Toxicology and applied pharmacology. 120(2)
Polybrominated dibenzo-p-dioxins and dibenzofurans are of major concern because of potential occupational and environmental exposures and their structural similarity to the highly toxic chlorinated analogues. 2,3,7,8-Tetrabromodibenzo-p-dioxin (TBDD)
Publikováno v:
Toxicology and applied pharmacology. 111(1)
The biologic activity and pharmacokinetic properties of 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) are similar to those of the chlorinated congener, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Metabolism of both compounds appears to be rate-limiting f