Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lorraine Washburn"'
Publikováno v:
Journal of Autoimmunity. 28:19-23
When nonobese-diabetic (NOD) mouse embryos were implanted into pseudopregnant mothers of a nonautoimmune mouse strain, the progeny had a reduced type 1 diabetes (T1D) incidence, suggesting that transmission of maternal autoantibodies is important for
Autor:
Jide Tian, Angelica P. Olcott, Blake Middleton, Hoa Dang, Valerie Walker, Daniel L. Kaufman, Luciano Adorini, Lorraine Washburn
Publikováno v:
The Journal of Immunology. 175:1991-1999
As organ-specific autoimmune diseases do not become manifest until well-advanced, interventive therapies must inhibit late-stage disease processes. Using a panel of immunogenic peptides from various β cell Ags, we evaluated the factors influencing t
Autor:
Lorraine Washburn, Hoa Dang, Blake Middleton, Mark A. Atkinson, Sanjiv S. Gambhir, Martha Campbell-Thompson, Yuxin Lu, Daniel L. Kaufman, Zesong Zhang, Jide Tian
Publikováno v:
Molecular Therapy. 9(3):428-435
Islet transplantation offers a potential therapy to restore glucose homeostasis in type 1 diabetes patients. A method to image transplanted islets noninvasively and repeatedly would greatly assist studies of islet transplantation. Using recombinant a
Autor:
Jide Tian, Daniel L. Kaufman, Blake Middleton, Hoa Dang, Lorraine Washburn, Christopher J. Evans, Shoshana Eitan, Yuxin Lu, Dan Zekzer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e18439 (2011)
PloS one, vol 6, iss 3
PLoS ONE, Vol 6, Iss 3, p e18439 (2011)
PloS one, vol 6, iss 3
The neurobiological activities of classical major histocompatibility class I (MHCI) molecules are just beginning to be explored. To further examine MHCI's actions during the formation of neuronal connections, we cultured embryonic mouse retina explan
Autor:
Hoa Dang, Jide Tian, Lorraine Washburn, Daniel L. Kaufman, Zhongqi-Phyllis Wu, Maia Boudzinskaia, Nathalie Escande-Beillard, Tina Bilousova, Cui-Wei Xie, Jyes Querubin
Publikováno v:
Journal of neuroimmunology. 232(1-2)
Mice deficient in classical major histocompatibility complex class I (MHCI) have aberrations in neurodevelopment. The consequences of upregulated neuronal MHCI expression have not been examined. We found that transgenic C57Bl/6 mice that are engineer
Autor:
Blake Middleton, Bonnie Wong, Nathalie Escande-Beillard, Hui Zhong, Hoa Dang, Jing Yong, Sharon Zdunowski, V. Reggie Edgerton, Daniel L. Kaufman, Niranjala J.K. Tillakaratne, Tina Bilousova, Maia Boudzinskaia, Zhongqi-Phyllis Wu, M. Selvan Joseph, Lorraine Washburn, Noore J. Ali
Publikováno v:
Journal of neuroscience research. 89(3)
Mice that are deficient in classical major histocompatibility complex class I (MHCI) have abnormalities in synaptic plasticity and neurodevelopment and have more extensive loss of synapses and reduced axon regeneration after sciatic nerve transection
Autor:
Lorraine Washburn, Christopher J. Evans, Hoa Dang, Blake Middleton, Dan Zekzer, Zhongqi-Phyllis Wu, Yoshitaka Yoshimura, Sebastian Joyce, Jide Tian, Shoshy Eitan, Sonja Ivkovic, Nathalie Escande-Beillard, Yuxin Lu, Daniel L. Kaufman, Tina Bilousova
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(2)
Studies of mice lacking MHC class I (MHC I)-associated proteins have demonstrated a role for MHC I in neurodevelopment. A central question arising from these observations is whether neuronal recognition of MHC I has specificity for the MHC I allele p
Autor:
Martha Campbell-Thompson, Yuxin Lu, Blake Middleton, Jide Tian, Lorraine Washburn, Hoa Dang, Michael E. Phelps, Mark A. Atkinson, Daniel L. Kaufman, David B. Stout, Sanjiv S. Gambhir, Zesong Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(30)
Islet transplantation offers a potential therapy to restore glucose homeostasis in type 1 diabetes patients. However, islet transplantation is not routinely successful because most islet recipients gradually lose graft function. Furthermore, serologi