Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lorraine Sheehan-Hennessy"'
Autor:
Faridh Raja Mohamed, Anand Rose, Lorraine Sheehan-Hennessy, Susanne K. Pedersen, Kathryn Cornthwaite, Geraldine Laven-Law, Graeme P. Young, Erin L. Symonds, Jean M. Winter
Publikováno v:
Cancer Treatment and Research Communications, Vol 40, Iss , Pp 100838- (2024)
Background: Colorectal (CRC) and lung adenocarcinoma share many genetic and pathological similarities. A circulating tumor DNA (ctDNA) test for CRC may also be useful for detection of lung adenocarcinoma. This study determined if a methylated BCAT1/I
Externí odkaz:
https://doaj.org/article/6fac99e56f414604ac610992043f31f4
Autor:
George C. Mayne, Richard J. Woodman, David I. Watson, Tim Bright, Susan Gan, Reginald V. Lord, Michael J. Bourke, Angelique Levert-Mignon, Isabell Bastian, Tanya Irvine, Ann Schloithe, Marian Martin, Lorraine Sheehan-Hennessy, Damian J. Hussey
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7068
The biomarker development field within molecular medicine remains limited by the methods that are available for building predictive models. We developed an efficient method for conservatively estimating confidence intervals for the cross validation-d
Autor:
Jean M. Winter, Lorraine Sheehan-Hennessy, Beibei Yao, Susanne K. Pedersen, Molla M. Wassie, Michael Eaton, Michael Chong, Graeme P. Young, Erin L. Symonds
Publikováno v:
Cancer biomarkers : section A of Disease markers. 34(3)
BACKGROUND: Detection of circulating cell-free DNA (ccfDNA) methylated in BCAT1 and IKZF1 is sensitive for detection of colorectal cancer (CRC), but it is not known if these biomarkers are present in other common adenocarcinomas. OBJECTIVE: Compare m
Autor:
Jean M. Winter, Lorraine Sheehan-Hennessy, Susanne Kartin Pedersen, Graeme P. Young, Erin L. Symonds
Publikováno v:
Journal of Clinical Oncology. 40:597-597
597 Background: Pancreatic adenocarcinoma patients have poor survival outcomes and there are no non-invasive tests to aid diagnosis or therapy. Detection of circulating tumour DNA (ctDNA) methylated for BCAT1 and/or IKZF1 is over 60% sensitive for co
Autor:
Susanne K. Pedersen, Molla Mesele Wassie, Graeme P. Young, Lorraine Sheehan-Hennessy, Erin L. Symonds, Jean M. Winter
Publikováno v:
Journal of Clinical Oncology. 39:e15533-e15533
e15533 Background: Assays for circulating tumor DNA (ctDNA) have shown utility for cancer detection and management. It is important to demonstrate cancer specificity of targeted ctDNA biomarkers. Detection of methylated BCAT1 and IKZF1 ctDNA has show