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pro vyhledávání: '"Lorraine Marnell"'
Publikováno v:
The Journal of Immunology. 186:110.21-110.21
During an acute infection, serum levels of certain proteins will be increased dramatically at the early stage of the infection, which are so-called acute phase proteins (APPs). Among them, C-reactive protein (CRP) and Serum Amyloid A (SAA) are two ma
Autor:
Kristopher Marjon, Jinghua Lu, Lorraine Marnell, Ruipeng Wang, Carolyn Mold, Peter Sun, Terry Du Clos
Publikováno v:
The Journal of Immunology. 186:110.22-110.22
C-Reactive Protein (CRP) is a member of the pentraxin family and an acute phase serum protein. It has been established that CRP and other pentraxins bind FcγRs and induce phagocytosis, activation of signaling, and cytokine synthesis. We report a nov
Publikováno v:
The Journal of Immunology. 184:136.42-136.42
The classical pentraxins include serum amyloid P component (SAP) and C-reactive protein (CRP), which are two of the acute-phase proteins and able to opsonize microbial pathogens. In 2008, we reported the structural mechanism for pentraxin’s binding